Recombinant Human CLEC10A/CD301 Protein, CF | R&D Systems 4888-CL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CLEC10A/CD301 Protein, CF

catalog :

4888-CL-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Wan Y, Adair K, Herrmann A, Shan X, Xia L, Duckworth C, et al. C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progression. Cell Death Dis. 2023;14:547 pubmed publisher
Hadjialirezaei S, Picco G, Beatson R, Burchell J, Stokke B, Sletmoen M. Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers. PLoS ONE. 2017;12:e0175323 pubmed publisher
Beatson R, Maurstad G, Picco G, Arulappu A, Coleman J, Wandell H, et al. The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL. PLoS ONE. 2015;10:e0125994 pubmed publisher
Akinc A, Querbes W, De S, Qin J, Frank Kamenetsky M, Jayaprakash K, et al. Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms. Mol Ther. 2010;18:1357-64 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

4888-CL

SKU :

4888-CL-050

product name :

Recombinant Human CLEC10A/CD301 Protein, CF

Description :

The Recombinant Human CLEC10A/CD301 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CLEC10A/CD301 Protein, CF has been validated for the following applications: Binding Activity.

target :

CLEC10A/CD301

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

40-43 kDa, reducing conditions

theoretical molecular weight :

29.6 kDa

gene symbol :

CLEC10A

details of functionality :

Measured by its ability to bind biotinylated beta-Galactosamine-N-Acetyl-Polyacrylamide ( beta-Gal-NAc-PAA) in a functional ELISA.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q8IUN9

applications :

Binding Activity

source :

NS0-derived Recombinant Human CLEC10A/CD301 Protein

USD :

447 USD

alt names :

CD301, CD301 antigen, CD301C-type lectin domain family 10 member A, CLECSF13, CLECSF14, CLECSF14macrophage C-type lectin, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 14 (macrophage-derived), C-type lectin domain family 10, member A, C-type lectin superfamily member 14, HML2, HMLC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 13 (macrophage-derived), Macrophage lectin 2, macrophage lectin 2 (calcium dependent), MGL

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage