product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Angiopoietin-like 4 Protein, CF
catalog :
4880-AN-050
quantity :
50 ug
price :
421 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Jung K, Son M, Yan H, Fang Z, Kim J, Kim S, et al. ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a. EMBO Mol Med. 2020;12:e11222 pubmed publisher
Zhang B, Xu X, Chu X, Yu X, Zhao Y. Protective effects of angiopoietin-like 4 on the blood-brain barrier in acute ischemic stroke treated with thrombolysis in mice. Neurosci Lett. 2017;645:113-120 pubmed publisher
Ben Zvi D, Barrandon O, Hadley S, Blum B, Peterson Q, Melton D. Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism. Proc Natl Acad Sci U S A. 2015;112:15498-503 pubmed publisher
product information
brand :
R&D Systems
master code :
4880-AN
SKU :
4880-AN-050
product name :
Recombinant Mouse Angiopoietin-like 4 Protein, CF
unit size :
50 ug
description :
Selective TLR3 inhibitor
target :
Angiopoietin-like Protein 4/ANGPTL4
category :
Proteins and Enzymes
alt names :
Angiopoietin like Protein 4, angiopoietin-like 4, Angiopoietin-like protein 4, ANGPTL4, ARP4fasting-induced adipose factor, FIAF, FIAFhepatic angiopoietin-related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, HFARPANGPTL2, NL2, peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein, PGAR, PGARangiopoietin-related protein 4, pp1158, PPARG angiopoietin related protein
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.
conjugate :
Unconjugated
all available conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
55-65 kDa, reducing conditions
theoretical molecular weight :
44.2 kDa
gene symbol :
Angptl4
details of functionality :
Measured by its ability to inhibit lipoprotein lipase activity. Yoshida, K. et al . (2002) J. Lipid Res. 43 :1770. The IC50 value under conditions in which Recombinant Human Lipoprotein Lipase/LPL (Catalog # 9888-LL ) and p-nitrophenyl butyrate are present in 0.1 M sodium phosphate, 0.15 M NaCl, 0.5% Triton® X-100, pH 7.2, is approximately 0.1-1 µg/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q9Z1P8
applications :
Inhibition Activity
source :
CHO-derived Recombinant Mouse Angiopoietin-like 4 Protein, CF
USD :
389
Jul-22 :
421 USD
sizes available :
50 ug
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.