Recombinant Mouse Angiopoietin-like 4 Protein, CF | R&D Systems 4880-AN-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Angiopoietin-like 4 Protein, CF

catalog :

4880-AN-050

quantity :

50 ug

price :

468 USD

citations: 5

Reference
Son Y, Lorenz W, Paton C. Linoleic acid-induced ANGPTL4 inhibits C2C12 skeletal muscle differentiation by suppressing Wnt/β-catenin. J Nutr Biochem. 2023;116:109324 pubmed publisher
Cho D, Ahn M, Cho H, Cho M, Jun J, Kang B, et al. ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation. Exp Mol Med. 2023;55:426-442 pubmed publisher
Jung K, Son M, Yan H, Fang Z, Kim J, Kim S, et al. ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a. EMBO Mol Med. 2020;12:e11222 pubmed publisher
Zhang B, Xu X, Chu X, Yu X, Zhao Y. Protective effects of angiopoietin-like 4 on the blood-brain barrier in acute ischemic stroke treated with thrombolysis in mice. Neurosci Lett. 2017;645:113-120 pubmed publisher
Ben Zvi D, Barrandon O, Hadley S, Blum B, Peterson Q, Melton D. Angptl4 links Î±-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism. Proc Natl Acad Sci U S A. 2015;112:15498-503 pubmed publisher

product information

master code :

4880-AN

SKU :

4880-AN-050

product name :

Recombinant Mouse Angiopoietin-like 4 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Angiopoietin-like 4 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Angiopoietin-like 4 Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Angiopoietin-like Protein 4/ANGPTL4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

55-65 kDa, reducing conditions

theoretical molecular weight :

44.2 kDa

gene symbol :

Angptl4

details of functionality :

Measured by its ability to inhibit lipoprotein lipase activity. Yoshida, K. et al . (2002) J. Lipid Res. 43 :1770. The IC50 value under conditions in which Recombinant Human Lipoprotein Lipase/LPL (Catalog # 9888-LL ) and p-nitrophenyl butyrate are present in 0.1 M sodium phosphate, 0.15 M NaCl, 0.5% Triton« X-100, pH 7.2, is approximately 0.1-1 ╡g/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9Z1P8

applications :

Inhibition Activity

source long :

Chinese Hamster Ovary cell line, CHO-derived mouse Angiopoietin-like Protein 4/ANGPTL4 protein Gln24-Ser410, with a C-terminal 6-His tag

source short :

CHO

USD :

468 USD

alt names :

Angiopoietin like Protein 4, angiopoietin-like 4, Angiopoietin-like protein 4, ANGPTL4, ARP4fasting-induced adipose factor, FIAF, FIAFhepatic angiopoietin-related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, HFARPANGPTL2, NL2, peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein, PGAR, PGARangiopoietin-related protein 4, pp1158, PPARG angiopoietin related protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.