Recombinant Mouse XCL1/Lymphotactin Protein | R&D Systems 486-LT-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse XCL1/Lymphotactin Protein

catalog :

486-LT-025

quantity :

25 ug

price :

423 USD

citations: 8

Reference
Mizumoto Y, Hemmi H, Katsuda M, Miyazawa M, Kitahata Y, Miyamoto A, et al. Anticancer effects of chemokine-directed antigen delivery to a cross-presenting dendritic cell subset with immune checkpoint blockade. Br J Cancer. 2020;122:1185-1193 pubmed publisher
Sharif S, Ueda N, Nakatani Y, Wise L, Clifton S, Lateef Z, et al. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity. Front Microbiol. 2019;10:1421 pubmed publisher
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed publisher
Li K, Wei G, Cao Y, Li D, Li P, Zhang J, et al. The Identification and Distribution of Cattle XCR1 and XCL1 among Peripheral Blood Cells: New Insights into the Design of Dendritic Cells Targeted Veterinary Vaccine. PLoS ONE. 2017;12:e0170575 pubmed publisher
Myster F, Palmeira L, Sorel O, Bouillenne F, Depauw E, Schwartz Cornil I, et al. Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever. J Virol. 2015;89:3630-47 pubmed publisher
Yamanaka H, Hoyt T, Yang X, Bowen R, Golden S, Crist K, et al. A parenteral DNA vaccine protects against pneumonic plague. Vaccine. 2010;28:3219-30 pubmed publisher
Rogers C, Zaharoff D, Hance K, Perkins S, Hursting S, Schlom J, et al. Exercise enhances vaccine-induced antigen-specific T cell responses. Vaccine. 2008;26:5407-15 pubmed publisher
Ordway D, Higgins D, Sanchez Campillo J, Spencer J, Henao Tamayo M, Harton M, et al. XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection with Mycobacterium tuberculosis negatively affects production of IFN-gamma by CD4 T cells and participates in granuloma stability. J Leukoc Biol. 2007;82:1221-9 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

486-LT

SKU :

486-LT-025

product name :

Recombinant Mouse XCL1/Lymphotactin Protein

Description :

The Recombinant Mouse XCL1/Lymphotactin Protein from R&D Systems is derived from E. coli. The Recombinant Mouse XCL1/Lymphotactin Protein has been validated for the following applications: Bioactivity.

target :

XCL1/Lymphotactin

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

theoretical molecular weight :

10 kDa

gene symbol :

Xcl1

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human XCR1. The ED50 for this effect is 0.05-0.1 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAA56752.1

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse XCL1/Lymphotactin Protein

USD :

423 USD

alt names :

ATAC, ATACSmall-inducible cytokine C1, C motif chemokine 1, chemokine (C motif) ligand 1, Cytokine SCM-1, LPTNSCM-1-alpha, LTNXC chemokine ligand 1, lymphotactin, lymphotaxin, SCM-1, SCM-1 alpha, SCM-1a, SCM1A, SCYC1SCM1, single cysteine motif 1a, small inducible cytokine subfamily C, member 1 (lymphotactin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.