Reference |
---|
Meyer T, Shimon D, Youssef S, Yankovitz G, Tessler A, Chernobylsky T, et al. NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity. Proc Natl Acad Sci U S A. 2022;119:e2211310119 pubmed publisher
|
Chandrasekaran S, Kochanowsky J, Merritt E, Lagas J, Swannigan A, Koshy A. IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii. Nat Commun. 2022;13:4605 pubmed publisher
|
Vasquez E, Nasreddin N, Valbuena G, Mulholland E, Belnoue Davis H, Eggington H, et al. Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia. Cell Stem Cell. 2022;29:1213-1228.e8 pubmed publisher
|
Qu H, Heinb xe4 ck R, Salo H, Ewing E, Espinosa A, Aulin C, et al. Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1. Biomolecules. 2022;12: pubmed publisher
|
Jin Y, Liu Y, Xu L, Xu J, Xiong Y, Peng Y, et al. Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis. Cell Death Dis. 2022;13:512 pubmed publisher
|
Mary R, Chalmin F, Accogli T, Bruchard M, Hibos C, Melin J, et al. Hematopoietic Prostaglandin D2 Synthase Controls Tfh/Th2 Communication and Limits Tfh Antitumor Effects. Cancer Immunol Res. 2022;10:900-916 pubmed publisher
|
Vasudevan S, Russo A, Kumari P, Vanaja S, Rathinam V. A TLR4-independent critical role for CD14 in intracellular LPS sensing. Cell Rep. 2022;39:110755 pubmed publisher
|
Steiner A, Hrovat Schaale K, Prigione I, Yu C, Laohamonthonkul P, Harapas C, et al. Deficiency in coatomer complex I causes aberrant activation of STING signalling. Nat Commun. 2022;13:2321 pubmed publisher
|
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
|
Yang M, Horstman S, Gee R, Guyer P, Lam T, Kanyo J, et al. Citrullination of glucokinase is linked to autoimmune diabetes. Nat Commun. 2022;13:1870 pubmed publisher
|
Liu L, Lucas R, Nanson J, Li Y, Whitfield J, Curson J, et al. The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs. J Biol Chem. 2022;298:101857 pubmed publisher
|
Stancic A, Saksida T, Markelic M, Vucetic M, Grigorov I, Martinović V, et al. Ferroptosis as a Novel Determinant of β-Cell Death in Diabetic Conditions. Oxid Med Cell Longev. 2022;2022:3873420 pubmed publisher
|
Fedoriw A, Shi L, O Brien S, Smitheman K, Wang Y, Hou J, et al. Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses. Cancer Immunol Res. 2022;10:420-436 pubmed publisher
|
Tuffs S, Goncheva M, Xu S, Craig H, Kasper K, Choi J, et al. Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
|
Jin J, Sivakumar I, Mironchik Y, Krishnamachary B, Wildes F, Barnett J, et al. PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model. Cancers (Basel). 2022;14: pubmed publisher
|
Arafa E, Shenoy A, Barker K, Etesami N, Martin I, Lyon de Ana C, et al. Recruitment and training of alveolar macrophages after pneumococcal pneumonia. JCI Insight. 2022;7: pubmed publisher
|
Wang Z, Huang K, Xu J, Liu J, Zheng Y. Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines. J Immunol Res. 2022;2022:4542487 pubmed publisher
|
Miranda J, Schleicher W, Wells K, Ramirez D, Landgrave S, Benninger R. Dynamic changes in β-cell [Ca2+] regulate NFAT activation, gene transcription, and islet gap junction communication. Mol Metab. 2022;57:101430 pubmed publisher
|
Mo H, Ren Q, Song D, Xu B, Zhou D, Hong X, et al. CXCR4 induces podocyte injury and proteinuria by activating β-catenin signaling. Theranostics. 2022;12:767-781 pubmed publisher
|
Cheng Y, Hall T, Xu X, Yung I, Souza D, Zheng J, et al. Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease. EBioMedicine. 2022;75:103758 pubmed publisher
|
Zhang Y, Zheng Y, Shu F, Zhou R, Bao B, Xiao S, et al. In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair. Carbohydr Polym. 2022;276:118752 pubmed publisher
|
McMurray H, Ambeskovic A, Newman L, Aldersley J, Balakrishnan V, Smith B, et al. Gene network modeling via TopNet reveals functional dependencies between diverse tumor-critical mediator genes. Cell Rep. 2021;37:110136 pubmed publisher
|
Chauhan P, Sheng W, Hu S, Prasad S, Lokensgard J. Differential Cytokine-Induced Responses of Polarized Microglia. Brain Sci. 2021;11: pubmed publisher
|
Fu A, van Rooyen L, Evans L, Armstrong N, Avizonis D, Kin T, et al. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets. Cell Rep. 2021;37:110037 pubmed publisher
|
Amo Aparicio J, Garcia Garcia J, Francos Quijorna I, Urpi A, Esteve Codina A, Gut M, et al. Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury. Theranostics. 2021;11:9805-9820 pubmed publisher
|
Wu K, Long K, Lin H, Siu P, Hoo R, Ye D, et al. The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages. Nat Commun. 2021;12:6637 pubmed publisher
|
Rozier P, Maumus M, Maria A, Toupet K, Jorgensen C, Guilpain P, et al. Lung Fibrosis Is Improved by Extracellular Vesicles from IFNγ-Primed Mesenchymal Stromal Cells in Murine Systemic Sclerosis. Cells. 2021;10: pubmed publisher
|
Motta J, Rumjanek V, Mantovani A, Locati M. Tumor-Released Products Promote Bone Marrow-Derived Macrophage Survival and Proliferation. Biomedicines. 2021;9: pubmed publisher
|
Progatzky F, Shapiro M, Chng S, García Cassani B, Classon C, Sevgi S, et al. Regulation of intestinal immunity and tissue repair by enteric glia. Nature. 2021;599:125-130 pubmed publisher
|
Wang G, Xie L, Li B, Sang W, Yan J, Li J, et al. A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis. Nat Commun. 2021;12:5733 pubmed publisher
|
Qian Z, Yang H, Li H, Liu C, Yang L, Qu Z, et al. The Cholinergic Anti-Inflammatory Pathway Attenuates the Development of Atherosclerosis in Apoe-/- Mice through Modulating Macrophage Functions. Biomedicines. 2021;9: pubmed publisher
|
Popoola T, Guetchueng S, Ritchie K, Awodele O, Dempster N, Akinloye O, et al. Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea. BMC Complement Med Ther. 2021;21:234 pubmed publisher
|
Lee S, Kalugotla G, Ingle H, Rodgers R, Wu C, Wang Y, et al. Intestinal antiviral signaling is controlled by autophagy gene Epg5 independent of the microbiota. Autophagy. 2021;:1-16 pubmed publisher
|
Choi M, Bonanno J. Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium. Invest Ophthalmol Vis Sci. 2021;62:4 pubmed publisher
|
Gluschko A, Farid A, Herb M, Grumme D, Kronke M, Schramm M. Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways. Autophagy. 2021;:1-18 pubmed publisher
|
Osman A, Yan B, Li Y, Pavelko K, Quandt J, Saadalla A, et al. TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer. Nat Immunol. 2021;22:1152-1162 pubmed publisher
|
Sumi K, Sakuda M, Munakata K, Nakamura K, Ashida K. α-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFα/IFNγ Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube. Nutrients. 2021;13: pubmed publisher
|
Kim J, Han J, Suk K. Protective Effects of Complement Component 8 Gamma Against Blood-Brain Barrier Breakdown. Front Physiol. 2021;12:671250 pubmed publisher
|
Sadek J, Hall D, Colalillo B, Omer A, Tremblay A, Sanguin Gendreau V, et al. Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects. EMBO Mol Med. 2021;13:e13591 pubmed publisher
|
Totten S, Im Y, Cepeda Cañedo E, Najyb O, Nguyen A, Hebert S, et al. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer. Nat Commun. 2021;12:3299 pubmed publisher
|
Preda M, Neculachi C, Fenyo I, Vacaru A, Publik M, Simionescu M, et al. Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice. Cell Death Dis. 2021;12:566 pubmed publisher
|
Qin S, Han B, Williams A, Jackson K, Jewell R, Chacon A, et al. Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model. Cancers (Basel). 2021;13: pubmed publisher
|
Wang Z, Deng C, Zheng Y. Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction. Mediators Inflamm. 2021;2021:5566453 pubmed publisher
|
Zhou J, Zhang N, Zhang W, Lu C, Xu F. The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation. Cell Biosci. 2021;11:84 pubmed publisher
|
Vijayaraj S, Feltham R, Rashidi M, Frank D, Liu Z, Simpson D, et al. The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation. Nat Commun. 2021;12:2713 pubmed publisher
|
Shi H, Sun L, Wang Y, Liu A, Zhan X, Li X, et al. N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization. Nat Commun. 2021;12:1379 pubmed publisher
|
Tallón de Lara P, Castañón H, Vermeer M, Nuñez N, Silina K, Sobottka B, et al. CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer. Nat Commun. 2021;12:769 pubmed publisher
|
Lopez Yglesias A, Burger E, Camanzo E, Martin A, Araujo A, Kwok S, et al. T-bet-dependent ILC1- and NK cell-derived IFN-γ mediates cDC1-dependent host resistance against Toxoplasma gondii. PLoS Pathog. 2021;17:e1008299 pubmed publisher
|
Sanmarco L, Wheeler M, Gutiérrez Vázquez C, Polonio C, Linnerbauer M, Pinho Ribeiro F, et al. Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature. 2021;: pubmed publisher
|
Contreras Lopez R, Elizondo Vega R, Luque Campos N, Torres M, Pradenas C, Tejedor G, et al. The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential. Theranostics. 2021;11:445-460 pubmed publisher
|
Carratalá J, Brouillette E, Serna N, Sánchez Chardi A, Sanchez J, Villaverde A, et al. In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics. Pharmaceutics. 2020;12: pubmed publisher
|
Rajput S, Mirza M, Choudhary M. Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells. PLoS ONE. 2020;15:e0241349 pubmed publisher
|
Tuttle K, Waugh K, Araya P, Minter R, Orlicky D, Ludwig M, et al. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020;33:108407 pubmed publisher
|
Han C, Kang I, Omer M, Wang S, Wietecha T, Wight T, et al. Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties. JCI Insight. 2020;5: pubmed publisher
|
Hur J, Frost G, Wu X, Crump C, Pan S, Wong E, et al. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease. Nature. 2020;586:735-740 pubmed publisher
|
Nolan K, Verzosa G, Cleaver T, Tippimanchai D, DePledge L, Wang X, et al. Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models. Cancer Cell Int. 2020;20:417 pubmed publisher
|
Leite A, Oliveira D, Mota L, Carvalho L, Zimmermann F, Paiva N, et al. Ectonucleotidases from trypomastigotes from different sources and various genetic backgrounds of Trypanosoma cruzi potentiate their infectivity and host inflammation. Cytokine. 2020;136:155255 pubmed publisher
|
Tur J, Pereira Lopes S, Vico T, Marín E, Muñoz J, Hernández Alvarez M, et al. Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity. Cell Rep. 2020;32:108079 pubmed publisher
|
Meerschaert K, Adelman P, Friedman R, Albers K, Koerber H, Davis B. Unique Molecular Characteristics of Visceral Afferents Arising from Different Levels of the Neuraxis: Location of Afferent Somata Predicts Function and Stimulus Detection Modalities. J Neurosci. 2020;40:7216-7228 pubmed publisher
|
Nelson A, Stephenson D, Bone R, Cardona C, Park M, Tusing Y, et al. Lipid mediators and biomarkers associated with type 1 diabetes development. JCI Insight. 2020;5: pubmed publisher
|
Castoldi A, Monteiro L, van Teijlingen Bakker N, Sanin D, Rana N, Corrado M, et al. Triacylglycerol synthesis enhances macrophage inflammatory function. Nat Commun. 2020;11:4107 pubmed publisher
|
Hong J, Yoon D, Nam Y, Seo D, Kim J, Kim M, et al. Lipopolysaccharide administration for a mouse model of cerebellar ataxia with neuroinflammation. Sci Rep. 2020;10:13337 pubmed publisher
|
Ettou S, Jung Y, Miyoshi T, Jain D, Hiratsuka K, Schumacher V, et al. Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury. Sci Adv. 2020;6:eabb5460 pubmed publisher
|
Luiz J, Toller Kawahisa J, Viacava P, Nascimento D, Pereira P, Saraiva A, et al. MEK5/ERK5 signaling mediates IL-4-induced M2 macrophage differentiation through regulation of c-Myc expression. J Leukoc Biol. 2020;108:1215-1223 pubmed publisher
|
Kapetanovic R, Afroz S, Ramnath D, Lawrence G, Okada T, Curson J, et al. Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages. Immunol Cell Biol. 2020;98:528-539 pubmed publisher
|
Wen Y, Lin J, Wu R, Yu S, Hsu C, Tseng G, et al. Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-O-β-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells. Molecules. 2020;25: pubmed publisher
|
Yan J, Pandey S, Barnes B, Turner J, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Rep. 2020;31:107820 pubmed publisher
|
Chaparala A, Tashkandi H, Chumanevich A, Witalison E, Windust A, Cui T, et al. Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2. Nutrients. 2020;12: pubmed publisher
|
Chaparala A, Poudyal D, Tashkandi H, Witalison E, Chumanevich A, Hofseth J, et al. Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice. Oncotarget. 2020;11:2026-2036 pubmed publisher
|
Mc Fie M, Koneva L, Collins I, Coveney C, Clube A, Chanalaris A, et al. Ciliary proteins specify the cell inflammatory response by tuning NFκB signalling, independently of primary cilia. J Cell Sci. 2020;133: pubmed publisher
|
Liu C, Zhang Y, Chen F, Wu X, Zhang B, Wu Z, et al. Immunopathology in schistosomiasis is regulated by TLR2,4- and IFN-γ-activated MSC through modulating Th1/Th2 responses. Stem Cell Res Ther. 2020;11:217 pubmed publisher
|
Hanschmann E, Petry S, Eitner S, Maresch C, Lingwal N, Lillig C, et al. Paracrine regulation and improvement of β-cell function by thioredoxin. Redox Biol. 2020;34:101570 pubmed publisher
|
Li M, Li C, Wu X, Chen T, Ren L, Xu B, et al. Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis. Crit Care. 2020;24:268 pubmed publisher
|
Yuan Q, Miao J, Yang Q, Fang L, Fang Y, Ding H, et al. Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation. Cell Death Dis. 2020;11:355 pubmed publisher
|
Bosteels C, Neyt K, Vanheerswynghels M, Van Helden M, Sichien D, Debeuf N, et al. Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection. Immunity. 2020;52:1039-1056.e9 pubmed publisher
|
Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
|
Wu T, Lin J, Luo Z, Hsu C, Wang J, Wu H. 2,3,4',5-Tetrahydroxystilbene-2-O-β-D-Glucoside (THSG) Activates the Nrf2 Antioxidant Pathway and Attenuates Oxidative Stress-Induced Cell Death in Mouse Cochlear UB/OC-2 Cells. Biomolecules. 2020;10: pubmed publisher
|
Kumar R, Bunn P, Singh S, Ng S, Montes De Oca M, de Labastida Rivera F, et al. Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis. Cell Rep. 2020;30:2512-2525.e9 pubmed publisher
|
Giri J, Das R, Nylen E, Chinnadurai R, Galipeau J. CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury. Cell Rep. 2020;30:1923-1934.e4 pubmed publisher
|
Gu X, Zhang Y, Li D, Cai H, Cai L, Xu Q. N6-methyladenosine demethylase FTO promotes M1 and M2 macrophage activation. Cell Signal. 2020;69:109553 pubmed publisher
|
Steinmann S, Schoedsack M, Heinrich F, Breda P, Ochel A, Tiegs G, et al. Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells. Sci Rep. 2020;10:1071 pubmed publisher
|
Ichii M, Oritani K, Toda J, Saito H, Shi H, Shibayama H, et al. Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress. Haematologica. 2020;: pubmed publisher
|
Delprat V, Tellier C, Demazy C, Raes M, Feron O, Michiels C. Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway. Sci Rep. 2020;10:882 pubmed publisher
|
Steffens N, Beuter Gunia C, Kravets E, Reich A, Legewie L, Pfeffer K, et al. Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection. MBio. 2020;11: pubmed publisher
|
Yan H, Fernandez M, Wang J, Wu S, Wang R, Lou Z, et al. B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching. J Immunol. 2020;204:1146-1157 pubmed publisher
|
Yoshida K, Okamoto M, Sasaki J, Kuroda C, Ishida H, Ueda K, et al. Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells. BMC Cancer. 2020;20:25 pubmed publisher
|
Ben Yehuda H, Matcovitch Natan O, Kertser A, Spinrad A, Prinz M, Amit I, et al. Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress. Mol Psychiatry. 2020;25:1050-1067 pubmed publisher
|
Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed publisher
|
Rahdar M, Rafiei A, Valipour Nouroozi R. The combination of Cytokines and albendazole therapy for prophylaxis and treatment of experimental/hydatid cyst. Acta Trop. 2020;201:105206 pubmed publisher
|
Liu J, Wei J, Wang C, Meng X, Chen H, Deng P, et al. The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-γ-induced immune destruction of hematopoiesis in bone marrow cells. BMC Complement Altern Med. 2019;19:356 pubmed publisher
|
Augustine J, Pavlou S, Ali I, Harkin K, Ozaki E, Campbell M, et al. IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment. J Neuroinflammation. 2019;16:251 pubmed publisher
|
Zhang D, Tang Z, Huang H, Zhou G, Cui C, Weng Y, et al. Metabolic regulation of gene expression by histone lactylation. Nature. 2019;574:575-580 pubmed publisher
|
Zammit N, Walters S, Seeberger K, O Connell P, Korbutt G, Grey S. A20 as an immune tolerance factor can determine islet transplant outcomes. JCI Insight. 2019;4: pubmed publisher
|
Claser C, Nguee S, Balachander A, Wu Howland S, Becht E, Gunasegaran B, et al. Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury. Nat Commun. 2019;10:4241 pubmed publisher
|
Bensellam M, Chan J, Lee K, Joglekar M, Hardikar A, Loudovaris T, et al. Phlda3 regulates beta cell survival during stress. Sci Rep. 2019;9:12827 pubmed publisher
|
Krashia P, Cordella A, Nobili A, La Barbera L, Federici M, Leuti A, et al. Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nat Commun. 2019;10:3945 pubmed publisher
|
El Kenawi A, Gatenbee C, Robertson Tessi M, Bravo R, Dhillon J, Balagurunathan Y, et al. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer. Br J Cancer. 2019;121:556-566 pubmed publisher
|
Cavalcante P, Alenina N, Budu A, Freitas Lima L, Alves Silva T, Agudelo J, et al. Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein. Mediators Inflamm. 2019;2019:9086758 pubmed publisher
|
Nakamura Y, Miyagawa S, Yoshida S, Sasawatari S, Toyofuku T, Toda K, et al. Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model. Sci Rep. 2019;9:10840 pubmed publisher
|
Lindahl H, Guerreiro Cacais A, Bedri S, Linnerbauer M, Lindén M, Abdelmagid N, et al. IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis. J Immunol. 2019;203:888-898 pubmed publisher
|
Ogando D, Choi M, Shyam R, Li S, Bonanno J. Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress. Redox Biol. 2019;26:101260 pubmed publisher
|
Pessoa C, Reis L, Ramos Sanchez E, Orikaza C, Cortez C, de Castro Levatti E, et al. ATP6V0d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis. PLoS Pathog. 2019;15:e1007834 pubmed publisher
|
Song G, Rahman M, Jha M, Gupta D, Park S, Kim J, et al. A Bcr-Abl Inhibitor GNF-2 Attenuates Inflammatory Activation of Glia and Chronic Pain. Front Pharmacol. 2019;10:543 pubmed publisher
|
Ano Y, Yoshino Y, Kutsukake T, Ohya R, Fukuda T, Uchida K, et al. Tryptophan-related dipeptides in fermented dairy products suppress microglial activation and prevent cognitive decline. Aging (Albany NY). 2019;11:2949-2967 pubmed publisher
|
Leal A, Misek S, Lisabeth E, Neubig R, Liby K. The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice. Sci Rep. 2019;9:7072 pubmed publisher
|
Nguyen T, Smith B, Elgass K, Creed S, Cheung S, Tate M, et al. SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm. J Immunol. 2019;: pubmed publisher
|
Vander Beken S, de Vries J, Meier Schiesser B, Meyer P, Jiang D, Sindrilaru A, et al. Newly Defined ATP-Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron-Overload Wounds via Secretion of Interleukin-1 Receptor Antagonist. Stem Cells. 2019;37:1057-1074 pubmed publisher
|
Giebel A, Hu S, Rajaram K, Finethy R, Toh E, Brothwell J, et al. Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture. MBio. 2019;10: pubmed publisher
|
Li L, Liu Y, Li S, Yang R, Zeng C, Rong W, et al. Signal regulatory protein α protects podocytes through promoting autophagic activity. JCI Insight. 2019;5: pubmed publisher
|
Wang J, Sun J, Liu L, Flies D, Nie X, Toki M, et al. Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy. Nat Med. 2019;25:656-666 pubmed publisher
|
Kita M, Ano Y, Inoue A, Aoki J. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells. Sci Rep. 2019;9:3135 pubmed publisher
|
Ryan P, Stolte E, London L, Wells J, Long S, Joyce S, et al. Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe. BMC Microbiol. 2019;19:33 pubmed publisher
|
Saeki Y, Ishiyama K, Ishida N, Tanaka Y, Ohdan H. Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation. Sci Rep. 2019;9:1022 pubmed publisher
|
Ano Y, Ohya R, Kita M, Taniguchi Y, Kondo K. Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation. Molecules. 2019;24: pubmed publisher
|
Paduch K, Debus A, Rai B, Schleicher U, Bogdan C. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1. J Immunol. 2019;202:1453-1464 pubmed publisher
|
Das L, Binko A, Traylor Z, Peng H, Lu K. Vitamin D improves sunburns by increasing autophagy in M2 macrophages. Autophagy. 2019;15:813-826 pubmed publisher
|
Freemerman A, Zhao L, Pingili A, Teng B, Cozzo A, Fuller A, et al. Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1. J Immunol. 2019;202:1265-1286 pubmed publisher
|
Felder M, Kapur A, Rakhmilevich A, Qu X, Sondel P, Gillies S, et al. MUC16 suppresses human and murine innate immune responses. Gynecol Oncol. 2019;152:618-628 pubmed publisher
|
Jones J, Sinder B, Paige D, Soki F, Koh A, Thiele S, et al. Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis. Neoplasia. 2019;21:172-184 pubmed publisher
|
Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher
|
Peng C, Hu Q, Yang F, Zhang H, Li F, Huang C. BCL6-Mediated Silencing of PD-1 Ligands in Germinal Center B Cells Maintains Follicular T Cell Population. J Immunol. 2019;202:704-713 pubmed publisher
|
Dou F, Chu X, Zhang B, Liang L, Lu G, Ding J, et al. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-κB signaling pathway. Mol Brain. 2018;11:75 pubmed publisher
|
Juban G, Saclier M, Yacoub Youssef H, Kernou A, Arnold L, Boisson C, et al. AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy. Cell Rep. 2018;25:2163-2176.e6 pubmed publisher
|
Zuo Z, Shen J, Pan Y, Pu J, Li Y, Shao X, et al. Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage. Cell Physiol Biochem. 2018;51:244-261 pubmed publisher
|
Falcão A, van Bruggen D, Marques S, Meijer M, Jäkel S, Agirre E, et al. Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis. Nat Med. 2018;24:1837-1844 pubmed publisher
|
Kim S, Jang H, Oh M, Lee J, Kang K. Tetrahydrocurcumin Enhances Islet Cell Function and Attenuates Apoptosis in Mouse Islets. Transplant Proc. 2018;50:2847-2853 pubmed publisher
|
Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
|
Zhang F, Ledue O, Jun M, Goulart C, Malley R, Lu Y. Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms. MBio. 2018;9: pubmed publisher
|
Farruggia C, Kim M, Bae M, Lee Y, Pham T, Yang Y, et al. Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners. J Nutr Biochem. 2018;62:202-209 pubmed publisher
|
Sang A, Danhorn T, Peterson J, Rankin A, O Connor B, Leach S, et al. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun. 2018;9:3973 pubmed publisher
|
Mobarak E, Håversen L, Manna M, Rutberg M, Levin M, Perkins R, et al. Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico. Sci Rep. 2018;8:13600 pubmed publisher
|
Ni Y, Wang X, Yin X, Li Y, Liu X, Wang H, et al. Plectin protects podocytes from adriamycin-induced apoptosis and F-actin cytoskeletal disruption through the integrin α6β4/FAK/p38 MAPK pathway. J Cell Mol Med. 2018;22:5450-5467 pubmed publisher
|
Kim S, Lee M, Choi J, Park D, Kwak H, Moon S, et al. Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression. Cell Physiol Biochem. 2018;48:1829-1842 pubmed publisher
|
Varanasi S, Rajasagi N, Jaggi U, Rouse B. Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions. Mucosal Immunol. 2018;11:1705-1715 pubmed publisher
|
Yin Y, Hao H, Cheng Y, Zang L, Liu J, Gao J, et al. Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice. Cell Death Dis. 2018;9:760 pubmed publisher
|
Martin A, Seignez C, Racoeur C, Isambert N, Mabrouk N, Scagliarini A, et al. Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment. Oncotarget. 2018;9:28364-28378 pubmed publisher
|
Jiang Y, Dai Y, Pan Y, Wu X, Yang Y, Bian K, et al. Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways. Evid Based Complement Alternat Med. 2018;2018:6714282 pubmed publisher
|
Nusse Y, Savage A, Marangoni P, Rosendahl Huber A, Landman T, De Sauvage F, et al. Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. Nature. 2018;559:109-113 pubmed publisher
|
Cramer Z, Sadek J, Vazquez G, Di Marco S, Pause A, Pelletier J, et al. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways. Sci Rep. 2018;8:8414 pubmed publisher
|
Hall D, Griss T, Ma J, Sanchez B, Sadek J, Tremblay A, et al. The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting. EMBO Mol Med. 2018;10: pubmed publisher
|
Su H, Zhang Z, Liu Z, Peng B, Kong C, Wang H, et al. Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells. J Biol Chem. 2018;293:10287-10302 pubmed publisher
|
Morrison B, Steel J, Morris J. Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells. BMC Cancer. 2018;18:469 pubmed publisher
|
Sharkey D, Glynn D, Schjenken J, Tremellen K, Robertson S. Interferon-gamma inhibits seminal plasma induction of colony-stimulating factor 2 in mouse and human reproductive tract epithelial cells. Biol Reprod. 2018;99:514-526 pubmed publisher
|
Joyce D, Fujino M, Morita M, Araki R, Fung J, Qian S, et al. Induced pluripotent stem cells-derived myeloid-derived suppressor cells regulate the CD8+ T cell response. Stem Cell Res. 2018;29:32-41 pubmed publisher
|
Yu Y, Li M, Zhang Z, Yu H. The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-?B pathways in CX3CR1-knock out mice. Int J Mol Med. 2018;41:3577-3585 pubmed publisher
|
O Reilly L, Putoczki T, Mielke L, Low J, Lin A, Preaudet A, et al. Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner. Immunity. 2018;48:570-583.e8 pubmed publisher
|
Liu Y, Liang X, Dong W, Fang Y, Lv J, Zhang T, et al. Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation. Cancer Cell. 2018;33:480-494.e7 pubmed publisher
|
Sun C, Chen S. RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function. J Immunol. 2018;200:2777-2785 pubmed publisher
|
Lin H, Wang J, Wang J, Li W, Wang X, Alston J, et al. GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function. Mol Metab. 2018;11:205-211 pubmed publisher
|
Chitre A, Kattah M, Rosli Y, Pao M, Deswal M, Deeks S, et al. A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog. 2018;14:e1006806 pubmed publisher
|
Lee K, Park N, Jung H, Rim Y, Nam Y, Lee J, et al. Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist. PLoS ONE. 2018;13:e0193086 pubmed publisher
|
Bhat P, Bergot A, Waterhouse N, Frazer I. Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells. Oncotarget. 2018;9:6015-6027 pubmed publisher
|
Chen M, Zhao J, Ali I, Marry S, Augustine J, Bhuckory M, et al. Cytokine Signaling Protein 3 Deficiency in Myeloid Cells Promotes Retinal Degeneration and Angiogenesis through Arginase-1 Up-Regulation in Experimental Autoimmune Uveoretinitis. Am J Pathol. 2018;188:1007-1020 pubmed publisher
|
Guedes C, Dias B, Petersen A, Cruz K, Almeida N, Andrade D, et al. In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195. Mem Inst Oswaldo Cruz. 2018;113:e170345 pubmed publisher
|
Das A, Yang C, Arifuzzaman S, Kim S, Kim S, Jung K, et al. High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages. Front Immunol. 2018;9:22 pubmed publisher
|
Stoll L, Sobel J, Rodríguez Trejo A, Guay C, Lee K, Venø M, et al. Circular RNAs as novel regulators of β-cell functions in normal and disease conditions. Mol Metab. 2018;9:69-83 pubmed publisher
|
Nishikimi A, Koyama Y, Ishihara S, Kobayashi S, Tometsuka C, Kusubata M, et al. Collagen-derived peptides modulate CD4+ T-cell differentiation and suppress allergic responses in mice. Immun Inflamm Dis. 2018;6:245-255 pubmed publisher
|
Burger E, Araujo A, López Yglesias A, Rajala M, Geng L, Levine B, et al. Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation. Cell Host Microbe. 2018;23:177-190.e4 pubmed publisher
|
Farnoodian M, Sorenson C, Sheibani N. PEDF expression affects the oxidative and inflammatory state of choroidal endothelial cells. Am J Physiol Cell Physiol. 2018;314:C456-C472 pubmed publisher
|
Zhang L, Liu J, Zhou F, Wang W, Chen N. PGC-1α ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism. Mol Med Rep. 2018;17:4490-4498 pubmed publisher
|
Mancini A, Tantucci M, Mazzocchetti P, de Iure A, Durante V, Macchioni L, et al. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis. Neurobiol Dis. 2018;113:97-108 pubmed publisher
|
Lin H, Muramatsu R, Maedera N, Tsunematsu H, Hamaguchi M, Koyama Y, et al. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis. EBioMedicine. 2018;27:71-85 pubmed publisher
|
Bruen R, Curley S, Kajani S, Crean D, O Reilly M, Lucitt M, et al. Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis. Cardiovasc Diabetol. 2017;16:143 pubmed publisher
|
Samant S, Kanwal A, Pillai V, Bao R, Gupta M. The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy. Sci Rep. 2017;7:11877 pubmed publisher
|
Smith S, Samokhin A, Alfadi M, Murphy E, Rhodes D, Holcombe W, et al. The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease. JACC Basic Transl Sci. 2017;2:398-414 pubmed publisher
|
Sorgi C, Zarini S, Martin S, Sanchez R, Scandiuzzi R, Gijón M, et al. Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid. Sci Rep. 2017;7:10981 pubmed publisher
|
Vadevoo S, Kim J, Gunassekaran G, Jung H, Chi L, Kim D, et al. IL4 Receptor-Targeted Proapoptotic Peptide Blocks Tumor Growth and Metastasis by Enhancing Antitumor Immunity. Mol Cancer Ther. 2017;16:2803-2816 pubmed publisher
|
Vaithilingam V, Evans M, Lewy D, Bean P, Bal S, Tuch B. Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted. Sci Rep. 2017;7:10059 pubmed publisher
|
Braverman J, Stanley S. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B. J Immunol. 2017;199:1805-1816 pubmed publisher
|
Nagalingam G, Vinuesa C, Britton W, Saunders B. Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation. J Immunol. 2017;199:1796-1804 pubmed publisher
|
Zhang W, Ogando D, Kim E, Choi M, Li H, Tenessen J, et al. Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model. Invest Ophthalmol Vis Sci. 2017;58:3723-3731 pubmed publisher
|
Foltz C, Napolitano A, Khan R, Clough B, Hirst E, Frickel E. TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles. Sci Rep. 2017;7:5209 pubmed publisher
|
Pei X, Zheng D, She S, Ma J, Guo C, Mo X, et al. The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis. Sci Rep. 2017;7:5107 pubmed publisher
|
Cunha D, Cito M, Grieco F, Cosentino C, Danilova T, Ladriere L, et al. Pancreatic ?-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF). J Biol Chem. 2017;292:14977-14988 pubmed publisher
|
Overgaard N, Cruz J, Bridge J, Nel H, Frazer I, La Gruta N, et al. CD4+CD8?+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. J Leukoc Biol. 2017;102:837-844 pubmed publisher
|
Kanbe A, Ito H, Omori Y, Hara A, Seishima M. The inhibition of NLRP3 signaling attenuates liver injury in an ?-galactosylceramide-induced hepatitis model. Biochem Biophys Res Commun. 2017;490:364-370 pubmed publisher
|
Iwata S, Mikami Y, Sun H, Brooks S, Jankovic D, Hirahara K, et al. The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells. Immunity. 2017;46:983-991.e4 pubmed publisher
|
Bhat P, Leggatt G, Waterhouse N, Frazer I. Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity. Cell Death Dis. 2017;8:e2836 pubmed publisher
|
Quinti L, Dayalan Naidu S, Träger U, Chen X, Kegel Gleason K, Lleres D, et al. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proc Natl Acad Sci U S A. 2017;114:E4676-E4685 pubmed publisher
|
Ledesma Colunga M, Adán N, Ortiz G, Solís Gutiérrez M, Lopez Barrera F, Martinez de la Escalera G, et al. Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis. Arthritis Res Ther. 2017;19:93 pubmed publisher
|
Schnettger L, Rodgers A, Repnik U, Lai R, Pei G, Verdoes M, et al. A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity. Cell Host Microbe. 2017;21:619-628.e5 pubmed publisher
|
Jee B, Sharma P, Katoch K, Joshi B, Awasthi S. IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage. Braz J Infect Dis. 2017;21:386-390 pubmed publisher
|
Park S, Sim H, Kim H, Jeong D, Wu G, Cho S, et al. CD11b regulates antibody class switching via induction of AID. Mol Immunol. 2017;87:47-59 pubmed publisher
|
Dharmarajan S, Fisk D, Sorenson C, Sheibani N, Belecky Adams T. Microglia activation is essential for BMP7-mediated retinal reactive gliosis. J Neuroinflammation. 2017;14:76 pubmed publisher
|
Nascimento D, Melo P, Piñeros A, Ferreira R, Cólon D, Donate P, et al. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nat Commun. 2017;8:14919 pubmed publisher
|
Morales A, Carrero J, Hung P, Tubbs A, Andrews J, Edelson B, et al. A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages. elife. 2017;6: pubmed publisher
|
Sireesh D, Ganesh M, Dhamodharan U, Sakthivadivel M, Sivasubramanian S, Gunasekaran P, et al. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade. J Nutr Biochem. 2017;44:11-21 pubmed publisher
|
Piccolo V, Curina A, Genua M, Ghisletti S, Simonatto M, Sabò A, et al. Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk. Nat Immunol. 2017;18:530-540 pubmed publisher
|
Cockrell D, Long C, Robertson S, Shannon J, Miller H, Myers L, et al. Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages. PLoS ONE. 2017;12:e0173528 pubmed publisher
|
Zhou Z, Wan J, Hou X, Geng J, Li X, Bai X. MicroRNA-27a promotes podocyte injury via PPAR?-mediated ?-catenin activation in diabetic nephropathy. Cell Death Dis. 2017;8:e2658 pubmed publisher
|
Dawicki W, Li C, Town J, Zhang X, Gordon J. Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3+CD49b-Foxp3- regulatory T cells. J Allergy Clin Immunol. 2017;139:1608-1620.e3 pubmed publisher
|
Ahn R, Sabourin V, Bolt A, Hebert S, Totten S, De Jay N, et al. The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression. Nat Commun. 2017;8:14638 pubmed publisher
|
Ma J, Sanchez B, Hall D, Tremblay A, Di Marco S, Gallouzi I. STAT3 promotes IFNγ/TNFα-induced muscle wasting in an NF-κB-dependent and IL-6-independent manner. EMBO Mol Med. 2017;9:622-637 pubmed publisher
|
Di Candia L, Gomez E, Venereau E, Chachi L, Kaur D, Bianchi M, et al. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4. J Allergy Clin Immunol. 2017;140:584-587.e8 pubmed publisher
|
Huang W, Fan W, Wang Y, Han D, Li X, Li S, et al. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway. Cell Death Discov. 2017;3:16097 pubmed publisher
|
Carmona Fontaine C, Deforet M, Akkari L, Thompson C, Joyce J, Xavier J. Metabolic origins of spatial organization in the tumor microenvironment. Proc Natl Acad Sci U S A. 2017;114:2934-2939 pubmed publisher
|
Villela A, Rodrigues V, Pinto A, Wink P, Sanchez Quitian Z, Petersen G, et al. Characterisation of iunH gene knockout strain from Mycobacterium tuberculosis. Mem Inst Oswaldo Cruz. 2017;112:203-208 pubmed publisher
|
Lau J, Cheung J, Navarro A, Lianoglou S, Haley B, Totpal K, et al. Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice. Nat Commun. 2017;8:14572 pubmed publisher
|
Gao S, Li C, Zhu Y, Wang Y, Sui A, Zhong Y, et al. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy. Sci Rep. 2017;7:42846 pubmed publisher
|
Szilagyi B, Triebus J, Kressler C, De Almeida M, Tierling S, Durek P, et al. Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4+ memory T cells. Mucosal Immunol. 2017;10:1443-1454 pubmed publisher
|
Jo M, Kim J, Song G, Seo M, Hwang E, Suk K. Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation. J Neurosci. 2017;37:2878-2894 pubmed publisher
|
Abraham N, Liu L, Jutras B, Yadav A, Narasimhan S, Gopalakrishnan V, et al. Pathogen-mediated manipulation of arthropod microbiota to promote infection. Proc Natl Acad Sci U S A. 2017;114:E781-E790 pubmed publisher
|
Lécuyer M, Saint Laurent O, Bourbonnière L, Larouche S, Larochelle C, Michel L, et al. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis. Proc Natl Acad Sci U S A. 2017;114:E524-E533 pubmed publisher
|
Guttman O, Freixo Lima G, Kaner Z, Lior Y, Rider P, Lewis E. Context-Specific and Immune Cell-Dependent Antitumor Activities of α1-Antitrypsin. Front Immunol. 2016;7:559 pubmed publisher
|
Dmytriyeva O, Pankratova S, Korshunova I, Walmod P. Epobis is a Nonerythropoietic and Neuroprotective Agonist of the Erythropoietin Receptor with Anti-Inflammatory and Memory Enhancing Effects. Mediators Inflamm. 2016;2016:1346390 pubmed
|
Kosmides A, Meyer R, Hickey J, Aje K, Cheung K, Green J, et al. Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma. Biomaterials. 2017;118:16-26 pubmed publisher
|
Watanabe M, Masaki K, Yamasaki R, Kawanokuchi J, Takeuchi H, Matsushita T, et al. Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation. Sci Rep. 2016;6:38387 pubmed publisher
|
Wang X, Zhao W, Ransohoff R, Zhou L. Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy. J Immunol. 2016;197:4750-4761 pubmed
|
Xue X, Soroosh P, De Leon Tabaldo A, Luna Roman R, Sablad M, Rozenkrants N, et al. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis. Sci Rep. 2016;6:37977 pubmed publisher
|
Yoon W, Park Y, Kim J, Chae Y, Byeon J, Min S, et al. Application of genetically engineered Salmonella typhimurium for interferon-gamma-induced therapy against melanoma. Eur J Cancer. 2017;70:48-61 pubmed publisher
|
Litteljohn D, Rudyk C, Razmjou S, Dwyer Z, Syed S, Hayley S. Individual and interactive sex-specific effects of acute restraint and systemic IFN-γ treatment on neurochemistry. Neurochem Int. 2017;102:95-104 pubmed publisher
|
Lim Y, Yi M, Choi J, Lee J, Han J, Jo S, et al. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections. Sci Rep. 2016;6:37211 pubmed publisher
|
Barnett F, Rosenfeld M, Wood M, Kiosses W, Usui Y, Marchetti V, et al. Macrophages form functional vascular mimicry channels in vivo. Sci Rep. 2016;6:36659 pubmed publisher
|
Yadranji Aghdam S, Mahmoudpour A. Proteasome Activators, PA28α and PA28β, Govern Development of Microvascular Injury in Diabetic Nephropathy and Retinopathy. Int J Nephrol. 2016;2016:3846573 pubmed
|
Peng H, Li H, Sheehy A, Cullen P, Allaire N, Scannevin R. Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments. J Neuroimmunol. 2016;299:35-44 pubmed publisher
|
Clark C, Gupta H, Sareddy G, Pandeswara S, Lao S, Yuan B, et al. Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma. Cancer Res. 2016;76:6964-6974 pubmed
|
Ashley J, Hancock W, Nelson A, Bone R, Tse H, Wohltmann M, et al. Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2? (Group VIA Phospholipase A2). J Biol Chem. 2016;291:23268-23281 pubmed
|
Evans R, Diamond M, Rech A, Chao T, Richardson M, Lin J, et al. Lack of immunoediting in murine pancreatic cancer reversed with neoantigen. JCI Insight. 2016;1: pubmed publisher
|
Braga T, Correa Costa M, Azevedo H, Silva R, Cruz M, Almeida M, et al. Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development. Immun Inflamm Dis. 2016;4:300-14 pubmed publisher
|
Spencer N, Schilling T, Miralles F, Eder C. Mechanisms Underlying Interferon-γ-Induced Priming of Microglial Reactive Oxygen Species Production. PLoS ONE. 2016;11:e0162497 pubmed publisher
|
Woo P, Lau S, Lau C, Tung E, Chong K, Yang F, et al. Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei. PLoS Negl Trop Dis. 2016;10:e0004907 pubmed publisher
|
Xu Q, Choksi S, Qu J, Jang J, Choe M, Banfi B, et al. NADPH Oxidases Are Essential for Macrophage Differentiation. J Biol Chem. 2016;291:20030-41 pubmed publisher
|
Braverman J, Sogi K, Benjamin D, Nomura D, Stanley S. HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis. J Immunol. 2016;197:1287-97 pubmed publisher
|
Cameron A, Morrison V, Levin D, Mohan M, Forteath C, Beall C, et al. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status. Circ Res. 2016;119:652-65 pubmed publisher
|
Frasch S, McNamee E, Kominsky D, Jedlicka P, Jakubzick C, Zemski Berry K, et al. G2A Signaling Dampens Colitic Inflammation via Production of IFN-?. J Immunol. 2016;197:1425-34 pubmed publisher
|
Batista Silva L, Rodrigues L, Vivarini A, Costa F, Mattos K, Costa M, et al. Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages. Sci Rep. 2016;6:27632 pubmed publisher
|
Guthrie L, Abiraman K, Plyler E, Sprenkle N, Gibson S, McFarland B, et al. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses. J Biol Chem. 2016;291:15830-40 pubmed publisher
|
Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed publisher
|
Dale M, Xiong W, Carson J, Suh M, Karpisek A, Meisinger T, et al. Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization. J Immunol. 2016;196:4536-43 pubmed publisher
|
Rothhammer V, Mascanfroni I, Bunse L, Takenaka M, Kenison J, Mayo L, et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med. 2016;22:586-97 pubmed publisher
|
Zuchtriegel G, Uhl B, Puhr Westerheide D, Pörnbacher M, Lauber K, Krombach F, et al. Platelets Guide Leukocytes to Their Sites of Extravasation. PLoS Biol. 2016;14:e1002459 pubmed publisher
|
Shou P, Chen Q, Jiang J, Xu C, Zhang J, Zheng C, et al. Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells. Oncogene. 2016;35:5953-5962 pubmed publisher
|
Shimojima C, Takeuchi H, Jin S, Parajuli B, Hattori H, Suzumura A, et al. Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis. J Immunol. 2016;196:4164-71 pubmed publisher
|
Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, et al. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9. Nat Biotechnol. 2016;34:184-191 pubmed publisher
|
Somintara S, Leardkamolkarn V, Suttiarporn P, Mahatheeranont S. Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia. PLoS ONE. 2016;11:e0146869 pubmed publisher
|
Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, et al. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol. 2015;195:4415-25 pubmed publisher
|
Cohen H, Ward A, Hamidzadeh K, Ravid K, Mosser D. IFN-γ Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response. J Immunol. 2015;195:3828-37 pubmed publisher
|
Gómez D, Diehl M, Crosby E, Weinkopff T, Debes G. Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation. J Immunol. 2015;195:3531-6 pubmed publisher
|
Howland S, Poh C, Rénia L. Activated Brain Endothelial Cells Cross-Present Malaria Antigen. PLoS Pathog. 2015;11:e1004963 pubmed publisher
|
Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, et al. Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate. Eur J Immunol. 2015;45:2494-503 pubmed publisher
|
Beck B, Kim H, O BRIEN R, Jadus M, Gillespie G, Cloud G, et al. Dynamics of Circulating γδ T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma. PLoS ONE. 2015;10:e0122387 pubmed publisher
|
Alam I, Gray A, Acton D, Gerard O Riley R, Reilly A, Econs M. Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice. J Bone Miner Res. 2015;30:2005-13 pubmed publisher
|
Guay C, Menoud V, Rome S, Regazzi R. Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells. Cell Commun Signal. 2015;13:17 pubmed publisher
|
Noh K, Son K, Jung I, Kang T, Choi C, Park Y. Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-γ-induced Indoleamine 2,3-Dioxygenase Expression. J Biol Chem. 2015;290:12394-402 pubmed publisher
|
Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E. Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis. PLoS ONE. 2015;10:e0120327 pubmed publisher
|
Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, et al. Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences. J Invest Dermatol. 2015;135:1771-1780 pubmed publisher
|
Sag D, Cekic C, Wu R, Linden J, Hedrick C. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun. 2015;6:6354 pubmed publisher
|
Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, et al. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat Neurosci. 2015;18:511-20 pubmed publisher
|
Goodsmith N, Guo X, Vandal O, Vaubourgeix J, Wang R, Botella H, et al. Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice. PLoS Pathog. 2015;11:e1004645 pubmed publisher
|
Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, et al. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization. Autophagy. 2015;11:271-84 pubmed publisher
|
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
|
Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, et al. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages. Genes Dev. 2015;29:394-408 pubmed publisher
|
Ma F, Li B, Liu S, Iyer S, Yu Y, Wu A, et al. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS. J Immunol. 2015;194:1545-54 pubmed publisher
|
Oficjalska K, Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, et al. Protective role for caspase-11 during acute experimental murine colitis. J Immunol. 2015;194:1252-60 pubmed publisher
|
Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, et al. Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells. PLoS ONE. 2014;9:e115198 pubmed publisher
|
Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Cancer Res. 2015;75:330-43 pubmed publisher
|
Dohi K, Kraemer B, Erickson M, McMillan P, Kovac A, Flachbartova Z, et al. Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. PLoS ONE. 2014;9:e108034 pubmed publisher
|
Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, et al. Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway. elife. 2014;3:e02809 pubmed publisher
|
Newstead S, Gates A, Hartley M, Rowland C, Williamson E, Lukaszewski R. Control of intracellular Francisella tularensis by different cell types and the role of nitric oxide. J Immunol Res. 2014;2014:694717 pubmed publisher
|
Mulye M, Bechill M, Grose W, Ferreira V, Lafontaine E, Wooten R. Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages. PLoS Negl Trop Dis. 2014;8:e2988 pubmed publisher
|
Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins A, Keech A, et al. Peroxisome proliferator-activated receptor ? protects capillary pericytes in the retina. Am J Pathol. 2014;184:2709-20 pubmed publisher
|
Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, et al. IFN-γ primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b. J Immunol. 2014;193:3036-44 pubmed publisher
|
Oslund K, Zhou X, Lee B, Zhu L, Duong T, Shih R, et al. Synergistic up-regulation of CXCL10 by virus and IFN ? in human airway epithelial cells. PLoS ONE. 2014;9:e100978 pubmed publisher
|
Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, et al. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis. Nat Commun. 2014;5:4436 pubmed publisher
|
Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, et al. Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-?. J Exp Med. 2014;211:1393-405 pubmed publisher
|
Stoolman J, Duncker P, Huber A, Segal B. Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis. J Immunol. 2014;193:564-70 pubmed publisher
|
Hong B, Li H, Lu Y, Zhang M, Zheng Y, Qian J, et al. USP18 is crucial for IFN-?-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity. Mol Cancer. 2014;13:132 pubmed publisher
|
Falconer J, Lowes K, Furmanski A, Dyson J, Ng W, Robinson J. Intramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan. Immunology. 2014;142:101-110 pubmed publisher
|
Hirosue S, Vokali E, Raghavan V, Rincon Restrepo M, Lund A, Corthésy Henrioud P, et al. Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells. J Immunol. 2014;192:5002-11 pubmed publisher
|
Bhatt S, Qin J, Bennett C, Qian S, Fung J, Hamilton T, et al. All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function. J Immunol. 2014;192:5098-108 pubmed publisher
|
Noubade R, Wong K, Ota N, Rutz S, Eidenschenk C, Valdez P, et al. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity. Nature. 2014;509:235-9 pubmed publisher
|
Cebrián C, Zucca F, Mauri P, Steinbeck J, Studer L, Scherzer C, et al. MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration. Nat Commun. 2014;5:3633 pubmed publisher
|
Wann A, Chapple J, Knight M. The primary cilium influences interleukin-1?-induced NF?B signalling by regulating IKK activity. Cell Signal. 2014;26:1735-42 pubmed publisher
|
Mboko W, Mounce B, Emmer J, Darrah E, Patel S, Tarakanova V. Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells. J Virol. 2014;88:6993-7004 pubmed publisher
|
Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma. J Immunol. 2014;192:3569-81 pubmed publisher
|
Yu C, Nguyen T, Irvine K, Sweet M, Frazer I, Blumenthal A. Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. Eur J Immunol. 2014;44:1480-90 pubmed publisher
|
Sriskantharajah S, Gückel E, Tsakiri N, Kierdorf K, Brender C, Ben Addi A, et al. Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase. J Immunol. 2014;192:3518-3529 pubmed publisher
|
van Solingen C, Araldi E, Chamorro Jorganes A, Fernandez Hernando C, Suarez Y. Improved repair of dermal wounds in mice lacking microRNA-155. J Cell Mol Med. 2014;18:1104-12 pubmed publisher
|
Fichtner Feigl S, Kesselring R, Martin M, Obermeier F, Ruemmele P, Kitani A, et al. IL-13 orchestrates resolution of chronic intestinal inflammation via phosphorylation of glycogen synthase kinase-3β. J Immunol. 2014;192:3969-80 pubmed publisher
|
Castro C, Barcala Tabarrozzi A, Winnewisser J, Gimeno M, Antunica Noguerol M, Liberman A, et al. Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes. Clin Exp Immunol. 2014;177:149-60 pubmed publisher
|
Olekhnovitch R, Ryffel B, Müller A, Bousso P. Collective nitric oxide production provides tissue-wide immunity during Leishmania infection. J Clin Invest. 2014;124:1711-22 pubmed publisher
|
Al Faraj A, Sultana Shaik A, Pureza M, Alnafea M, Halwani R. Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI. PLoS ONE. 2014;9:e90829 pubmed publisher
|
Suresh Babu S, Valdez Y, Xu A, O Byrne A, Calvo F, Lei V, et al. TGF?-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer. 2014;14:113 pubmed publisher
|
Tatano Y, Shimizu T, Tomioka H. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization. Sci Rep. 2014;4:4146 pubmed publisher
|
Bouwer A, Saunderson S, Caldwell F, Damani T, Pelham S, Dunn A, et al. NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge. J Immunol. 2014;192:2514-21 pubmed publisher
|
Gonzalvo Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, et al. Endothelial cell-derived chemerin promotes dendritic cell transmigration. J Immunol. 2014;192:2366-73 pubmed publisher
|
Ling W, Zhang J, Yuan Z, Ren G, Zhang L, Chen X, et al. Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironment. Cancer Res. 2014;74:1576-87 pubmed publisher
|
Alamuru N, Behera S, Butchar J, Tridandapani S, Kaimal Suraj S, Babu P, et al. A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages. J Leukoc Biol. 2014;95:775-783 pubmed
|
Veremeyko T, Siddiqui S, Sotnikov I, Yung A, Ponomarev E. IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation. PLoS ONE. 2013;8:e81774 pubmed publisher
|
Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, et al. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. J Immunol. 2014;192:59-72 pubmed publisher
|
Xu C, Yu P, Han X, Du L, Gan J, Wang Y, et al. TGF-? promotes immune responses in the presence of mesenchymal stem cells. J Immunol. 2014;192:103-9 pubmed publisher
|
Moon C, VanDussen K, Miyoshi H, Stappenbeck T. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis. Mucosal Immunol. 2014;7:818-28 pubmed publisher
|
Pereira Lopes S, Celhar T, Sans Fons G, Serra M, Fairhurst A, Lloberas J, et al. The exonuclease Trex1 restrains macrophage proinflammatory activation. J Immunol. 2013;191:6128-35 pubmed publisher
|
Sidney L, Kirkham G, Buttery L. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1?, TNF-?, and IFN-?. Stem Cells Dev. 2014;23:605-17 pubmed publisher
|
Jiang E, Perrard X, Yang D, Khan I, Perrard J, Smith C, et al. Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue. Arterioscler Thromb Vasc Biol. 2014;34:34-43 pubmed publisher
|
Steelman A, Smith R, Welsh C, Li J. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis. J Biol Chem. 2013;288:23776-87 pubmed publisher
|
Achard M, Chen K, Sweet M, Watts R, Schroder K, Schembri M, et al. An antioxidant role for catecholate siderophores in Salmonella. Biochem J. 2013;454:543-9 pubmed
|
Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, et al. Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/?-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria. J Biol Chem. 2013;288:23368-79 pubmed publisher
|
Selleck E, Fentress S, Beatty W, Degrandi D, Pfeffer K, Virgin H, et al. Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii. PLoS Pathog. 2013;9:e1003320 pubmed publisher
|
Hoffmann U, Pink M, Lauer U, Heimesaat M, Winsauer C, Kruglov A, et al. Regulation and migratory role of P-selectin ligands during intestinal inflammation. PLoS ONE. 2013;8:e62055 pubmed publisher
|
Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, et al. Anti-CD70 immunocytokines for exploitation of interferon-?-induced RIP1-dependent necrosis in renal cell carcinoma. PLoS ONE. 2013;8:e61446 pubmed publisher
|
Gaffal E, Cron M, Glodde N, Bald T, Kuner R, Zimmer A, et al. Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation. J Immunol. 2013;190:4929-36 pubmed publisher
|
Zhou H, Yan H, Cannon J, Springer L, Green J, Pham C. CD43-mediated IFN-? production by CD8+ T cells promotes abdominal aortic aneurysm in mice. J Immunol. 2013;190:5078-85 pubmed publisher
|
Bocian C, Urbanowitz A, Owens R, Iozzo R, Götte M, Seidler D. Decorin potentiates interferon-? activity in a model of allergic inflammation. J Biol Chem. 2013;288:12699-711 pubmed publisher
|
Park S, Dimaio T, Liu W, Wang S, Sorenson C, Sheibani N. Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-? signaling pathways. J Cell Sci. 2013;126:1392-405 pubmed publisher
|
Moran C, Jose R, Moxon J, Roomberg A, Norman P, Rush C, et al. Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes. Arterioscler Thromb Vasc Biol. 2013;33:814-21 pubmed publisher
|
Tian X, Zhang J, Tan T, Lyons J, Zhao H, Niu B, et al. Association of ?-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-?1. J Cell Sci. 2013;126:67-76 pubmed publisher
|
Jeyanathan M, Damjanovic D, Shaler C, Lai R, Wortzman M, Yin C, et al. Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity. Mucosal Immunol. 2013;6:612-25 pubmed publisher
|
Kim H, Chung D. IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner. Mucosal Immunol. 2013;6:347-57 pubmed publisher
|
Manohar M, Hirsh M, Chen Y, Woehrle T, Karande A, Junger W. ATP release and autocrine signaling through P2X4 receptors regulate ?? T cell activation. J Leukoc Biol. 2012;92:787-94 pubmed publisher
|
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
|
Vidal C, Bermeo S, Li W, Huang D, Kremer R, Duque G. Interferon gamma inhibits adipogenesis in vitro and prevents marrow fat infiltration in oophorectomized mice. Stem Cells. 2012;30:1042-8 pubmed publisher
|
Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu D, Yanaba M, et al. Host-derived MCP-1 and MIP-1? regulate protective anti-tumor immunity to localized and metastatic B16 melanoma. Am J Pathol. 2012;180:365-74 pubmed publisher
|
Silver J, Stumhofer J, Passos S, Ernst M, Hunter C. IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii. J Immunol. 2011;187:350-60 pubmed publisher
|
Nicholls H, Kowalski G, Kennedy D, Risis S, Zaffino L, Watson N, et al. Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. Diabetes. 2011;60:1100-10 pubmed publisher
|
Sato N, Sabzevari H, Fu S, Ju W, Petrus M, Bamford R, et al. Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15R?. Blood. 2011;117:4032-40 pubmed publisher
|
Liang S, Krauss J, Domon H, McIntosh M, Hosur K, Qu H, et al. The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss. J Immunol. 2011;186:869-77 pubmed publisher
|
Zaki M, Vogel P, Body Malapel M, Lamkanfi M, Kanneganti T. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol. 2010;185:4912-20 pubmed publisher
|
Blumberg H, Dinh H, Dean C, Trueblood E, Bailey K, Shows D, et al. IL-1RL2 and its ligands contribute to the cytokine network in psoriasis. J Immunol. 2010;185:4354-62 pubmed publisher
|
Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G, et al. Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo. Eur J Immunol. 2010;40:2391-400 pubmed publisher
|
Filardy A, Pires D, Nunes M, Takiya C, Freire de Lima C, Ribeiro Gomes F, et al. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages. J Immunol. 2010;185:2044-50 pubmed publisher
|
Craig E, Austin A, Vaillancourt R, Barnett J, Camenisch T. TGF?2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion. Exp Cell Res. 2010;316:3397-405 pubmed publisher
|
Chen X, Fang L, Song S, Guo T, Liu A, Zhang J. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway. J Immunol. 2009;183:6135-44 pubmed publisher
|
Kotarsky K, Sitnik K, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, et al. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Mucosal Immunol. 2010;3:40-8 pubmed publisher
|
Wu J, Wrathall J, Schachner M. Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. Glia. 2010;58:315-28 pubmed publisher
|
Ilarregui J, Croci D, Bianco G, Toscano M, Salatino M, Vermeulen M, et al. Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat Immunol. 2009;10:981-91 pubmed publisher
|
Aronoff D, Lewis C, Serezani C, Eaton K, Goel D, Phipps J, et al. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J Immunol. 2009;183:2642-9 pubmed publisher
|
Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, et al. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature. 2009;460:269-73 pubmed publisher
|
Lemos H, Grespan R, Vieira S, Cunha T, Verri W, Fernandes K, et al. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proc Natl Acad Sci U S A. 2009;106:5954-9 pubmed publisher
|
Wieland C, van der Windt G, Florquin S, McKenzie A, van der Poll T. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis. Microbes Infect. 2009;11:524-30 pubmed publisher
|
Cui W, Joshi N, Jiang A, Kaech S. Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation. Vaccine. 2009;27:2177-87 pubmed publisher
|
Bhowmick S, Mazumdar T, Ali N. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection. Infect Immun. 2009;77:1514-23 pubmed publisher
|
Dienz O, Eaton S, Bond J, Neveu W, Moquin D, Noubade R, et al. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells. J Exp Med. 2009;206:69-78 pubmed publisher
|
Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, et al. IFN-gamma down-regulates Secretoglobin 3A1 gene expression. Biochem Biophys Res Commun. 2009;379:964-8 pubmed publisher
|
Smith K, Fritzell S, Badn W, Eberstål S, Janelidze S, Visse E, et al. Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells. Int J Cancer. 2009;124:630-7 pubmed publisher
|
Liu T, Huang Y, Likhotvorik R, Keshvara L, Hoyt D. Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells. Am J Physiol Cell Physiol. 2008;295:C819-27 pubmed publisher
|
Nairz M, Fritsche G, Brunner P, Talasz H, Hantke K, Weiss G. Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium. Eur J Immunol. 2008;38:1923-36 pubmed publisher
|
Wieland C, van der Windt G, Wiersinga W, Florquin S, van der Poll T. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis. Immunology. 2008;125:272-9 pubmed publisher
|
Lee Y, Miyahara N, Takeda K, Prpich J, Oh A, Balhorn A, et al. IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus. Am J Respir Crit Care Med. 2008;177:208-18 pubmed
|
Smith S, Li J, Garbett K, Mirnics K, Patterson P. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci. 2007;27:10695-702 pubmed
|
Schell J, Crane C, Smith M, Roberts M. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia. J Neuroimmunol. 2007;189:75-87 pubmed
|
Fujita H, Asahina A, Komine M, Tamaki K. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells. Cell Immunol. 2007;245:70-9 pubmed
|
Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, et al. Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration. Am J Pathol. 2007;170:1695-712 pubmed
|
Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, et al. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis. J Immunol. 2006;177:8650-7 pubmed
|
Henke P, Pearce C, Moaveni D, Moore A, Lynch E, Longo C, et al. Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model. J Immunol. 2006;177:3388-97 pubmed
|
Butovsky O, Koronyo Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, et al. Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1. Proc Natl Acad Sci U S A. 2006;103:11784-9 pubmed
|
Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, et al. Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J Clin Invest. 2006;116:905-15 pubmed
|
An H, Jeong H, Um J, Kim H, Hong S. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. J Ethnopharmacol. 2006;106:418-24 pubmed
|
Zhang F, Lee J, Wang D, Dong Z. Differential growth of IFN-beta-engineered tumor cells in nude and IFN receptor-null mice. J Interferon Cytokine Res. 2006;26:108-18 pubmed
|
Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar A, Pluchino S, et al. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci. 2006;31:149-60 pubmed
|
Best S, Morris K, Shannon J, Robertson S, Mitzel D, Park G, et al. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J Virol. 2005;79:12828-39 pubmed
|
Osuchowski M, Siddiqui J, Copeland S, Remick D. Sequential ELISA to profile multiple cytokines from small volumes. J Immunol Methods. 2005;302:172-81 pubmed
|
Kamath A, Sheasby C, Tough D. Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma. J Immunol. 2005;174:767-76 pubmed
|
Murphey E, Herndon D, Sherwood E. Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression. Infect Immun. 2004;72:6892-901 pubmed
|
Zamboni D, Campos M, Torrecilhas A, Kiss K, Samuel J, Golenbock D, et al. Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J Biol Chem. 2004;279:54405-15 pubmed
|
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity. 2004;21:241-54 pubmed
|
Bleier J, Pillarisetty V, Shah A, Dematteo R. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow. J Immunol. 2004;172:7408-16 pubmed
|
Sharif M, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv L. IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis. J Immunol. 2004;172:6476-81 pubmed
|
Gough P, Garton K, Wille P, Rychlewski M, Dempsey P, Raines E. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. J Immunol. 2004;172:3678-85 pubmed
|
Asselin Paturel C, Brizard G, Pin J, Briere F, Trinchieri G. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J Immunol. 2003;171:6466-77 pubmed
|
Monick M, Samavati L, Butler N, Mohning M, Powers L, Yarovinsky T, et al. Intracellular thiols contribute to Th2 function via a positive role in IL-4 production. J Immunol. 2003;171:5107-15 pubmed
|
Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, et al. Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. J Exp Med. 2003;198:31-8 pubmed
|
Jakubzick C, Choi E, Kunkel S, Joshi B, Puri R, Hogaboam C. Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. Am J Pathol. 2003;162:1475-86 pubmed
|
Shi Z, Fischer M, De Sanctis G, Schuyler M, Tesfaigzi Y. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis. J Immunol. 2002;168:4764-71 pubmed
|