product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human LRP-1 Cluster III Fc Chimera Protein, CF
catalog :
4824-L3-050
quantity :
50 ug
price :
533 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Sakamoto K. Generation of KS-487 as a novel LRP1-binding cyclic peptide with higher affinity, higher stability and BBB permeability. Biochem Biophys Rep. 2022;32:101367 pubmed publisher
Tkaczynski E, Arulselvan A, Tkaczynski J, Avery S, Xiao L, Torok Storb B, et al. 2-O, 3-O desulfated heparin mitigates murine chemotherapy- and radiation-induced thrombocytopenia. Blood Adv. 2018;2:754-761 pubmed publisher
Young P, Migliorini M, Strickland D. Evidence That Factor VIII Forms a Bivalent Complex with the Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1): IDENTIFICATION OF CLUSTER IV ON LRP1 AS THE MAJOR BINDING SITE. J Biol Chem. 2016;291:26035-26044 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
4824-L3
SKU :
4824-L3-050
product name :
Recombinant Human LRP-1 Cluster III Fc Chimera Protein, CF
Description :
The Recombinant Human LRP-1 Cluster III Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human LRP-1 Cluster III Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
LRP-1 Cluster III
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
115-130 kDa, reducing conditions
theoretical molecular weight :
72.8 kDa (monomer)
gene symbol :
LRP1
details of functionality :
Measured by its binding ability in a functional ELISA. When recombinant human (rh) LRP-1 Cluster III Fc Chimera is immobilized at 50 ng/mL (100 µL/well), the concentration of rhLRPAP (Catalog # 4296-LR) that produces 50% of the optimal binding response is found to be approximately 1-5 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q07954
applications :
Bioactivity
source :
CHO-derived Recombinant Human LRP-1 Cluster III Fc Chimera Protein
USD :
533 USD
alt names :
A2MR;APOER;APR;CD91;IGFBP3R;IGFBP-3R;IGFBP3R1;KPA;LRP;LRP1A;Prolow-density lipoprotein receptor-related protein 1;TGFBR5, LRP1 Cluster III
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.