product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CCL25/TECK Protein, CF
catalog :
481-TK-025/CF
quantity :
25 ug
price :
417 USD
more info or order :
R&D Systems product webpage
citations: 15
Reference
Tereshchenko V, Bulygin A, Zavodskii R, Maksyutov A, Kurilin V, Fisher M, et al. The murine DCs transfected with DNA-plasmid encoding CCR9 demonstrate the increased migration to CCL25 and thymic cells in vitro and to the thymus in vivo. Cytokine. 2021;142:155473 pubmed publisher
Sato T, Ishihara S, Marui R, Takagi J, Katagiri K. Dissection of α4β7 integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β7 antibodies. Sci Rep. 2020;10:13221 pubmed publisher
Pontejo S, Sanchez C, Ruiz Argüello B, Alcami A. Insights into ligand binding by a viral tumor necrosis factor (TNF) decoy receptor yield a selective soluble human type 2 TNF receptor. J Biol Chem. 2019;294:5214-5227 pubmed publisher
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
Shukla S, Langley M, Singh J, Edgar J, Mohtashami M, Zuniga Pflucker J, et al. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1. Nat Methods. 2017;14:531-538 pubmed publisher
Chen H, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, et al. Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting. Nat Biotechnol. 2015;33:656-60 pubmed publisher
Graham K, Zhang J, Lewén S, BURKE T, Dang T, Zoudilova M, et al. A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. PLoS ONE. 2014;9:e112925 pubmed publisher
Miething C, Scuoppo C, Bosbach B, Appelmann I, Nakitandwe J, Ma J, et al. PTEN action in leukaemia dictated by the tissue microenvironment. Nature. 2014;510:402-6 pubmed publisher
Costa M, Bornstein V, Candéa A, Henriques Pons A, Henriques M, Penido C. CCL25 induces ???? integrin-dependent migration of IL-17? ?? T lymphocytes during an allergic reaction. Eur J Immunol. 2012;42:1250-60 pubmed publisher
McGuire H, Vogelzang A, Ma C, Hughes W, Silveira P, Tangye S, et al. A subset of interleukin-21+ chemokine receptor CCR9+ T helper cells target accessory organs of the digestive system in autoimmunity. Immunity. 2011;34:602-15 pubmed publisher
Penido C, Costa M, Souza M, Costa K, Candea A, Benjamim C, et al. Involvement of CC chemokines in gammadelta T lymphocyte trafficking during allergic inflammation: the role of CCL2/CCR2 pathway. Int Immunol. 2008;20:129-39 pubmed
Park E, Mora J, Carman C, Chen J, Sasaki Y, Cheng G, et al. Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut. J Clin Invest. 2007;117:2526-38 pubmed
Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed
Hieshima K, Kawasaki Y, Hanamoto H, Nakayama T, Nagakubo D, Kanamaru A, et al. CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells. J Immunol. 2004;173:3668-75 pubmed
product information
brand :
R&D Systems
master code :
481-TK/CF
SKU :
481-TK-025/CF
product name :
Recombinant Mouse CCL25/TECK Protein, CF
description :
The Recombinant Mouse CCL25/TECK Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CCL25/TECK Protein, CF has been validated for the following applications: Bioactivity.
target :
CCL25/TECK
category :
Proteins and Enzymes
sizes available :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
16-17 kDa doublet, reducing conditions
theoretical molecular weight :
14 kDa
gene symbol :
Ccl25
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR9. The ED50 for this effect is 0.1-0.5 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
O35903.1
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse CCL25/TECK Protein, CF
USD :
410
USD 2023 :
417 USD
alt names :
C-C motif chemokine 25, chemokine (C-C motif) ligand 25, Chemokine TECK, Ck beta-15, Ckb15, SCYA25TECKvar, small inducible cytokine subfamily A (Cys-Cys), member 25, Small-inducible cytokine A25, TECK, TECKMGC150327, thymus expressed chemokine, Thymus-expressed chemokine
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.