Wnt-4 Protein | R&D Systems 475-WN-005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Wnt-4 Protein

catalog :

475-WN-005

quantity :

5 ug

price :

398 USD

citations: 9

Reference
Eliazer S, Muncie J, Christensen J, Sun X, D Urso R, Weaver V, et al. Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells. Cell Stem Cell. 2019;25:654-665.e4 pubmed publisher
Hung L, Sen D, Oniskey T, Katzen J, Cohen N, Vaughan A, et al. Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism. Mucosal Immunol. 2019;12:64-76 pubmed publisher
Mata Miranda M, Vazquez Zapien G, Rojas Lopez M, Sánchez Monroy V, Pérez Ishiwara D, Delgado Macuil R. Morphological, molecular and FTIR spectroscopic analysis during the differentiation of kidney cells from pluripotent stem cells. Biol Res. 2017;50:14 pubmed publisher
Messéant J, Ezan J, Delers P, Glebov K, Marchiol C, Lager F, et al. Wnt proteins contribute to neuromuscular junction formation through distinct signaling pathways. Development. 2017;144:1712-1724 pubmed publisher
Hosseini H, Obradović M, Hoffmann M, Harper K, Sosa M, Werner Klein M, et al. Early dissemination seeds metastasis in breast cancer. Nature. 2016;540:552-558 pubmed publisher
Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, et al. Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary. Exp Cell Res. 2015;332:163-78 pubmed publisher
Pan H, Cui H, Liu S, Qian Y, Wu H, Li L, et al. Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway. Endocrinology. 2014;155:3624-37 pubmed publisher
Wang Y, Wu B, Chamberlain A, Lui W, Koirala P, Susztak K, et al. Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development. PLoS ONE. 2013;8:e60244 pubmed publisher
Alvarado D, Hawkins R, Bashiardes S, Veile R, Ku Y, Powder K, et al. An RNA interference-based screen of transcription factor genes identifies pathways necessary for sensory regeneration in the avian inner ear. J Neurosci. 2011;31:4535-43 pubmed publisher

product information

brand :

R&D Systems

SKU :

475-WN-005

product name :

Wnt-4 Protein

unit sizes :

5 ug

description :

The Recombinant Mouse Wnt-4 Protein from R&D Systems is derived from CHO. The Recombinant Mouse Wnt-4 Protein has been validated for the following applications: Bioactivity.

target :

Wnt-4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS, NaCl, EDTA and CHAPS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>60%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

43 kDa, reducing conditions

theoretical molecular weight :

36.6 kDa

gene symbol :

Wnt4

details of functionality :

Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 15-60 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

475-WN

accessionNumbers :

NP_033549

applications :

Bioactivity

source :

The Recombinant Mouse Wnt-4 Protein from R&D Systems is derived from CHO. The Recombinant Mouse Wnt-4 Protein has been validated for the following applications: Bioactivity.

USD :

398 USD

applications abr :

alt names :

protein Wnt-4, SERKAL, wingless-type MMTV integration site family, member 4, Wnt4, WNT-4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.