Recombinant Mouse Ephrin-B1 Fc Chimera Protein, CF | R&D Systems 473-EB-200 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Ephrin-B1 Fc Chimera Protein, CF

catalog :

473-EB-200

quantity :

200 ug

price :

313 USD

more info or order :

R&D Systems product webpage

citations: 24

Reference
Laing E, Navaratnarajah C, Cheliout Da Silva S, Petzing S, Xu Y, Sterling S, et al. Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc Natl Acad Sci U S A. 2019;116:20707-20715 pubmed publisher
Fawal M, Jungas T, Kischel A, Audouard C, Iacovoni J, Davy A. Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Cell Rep. 2018;23:2864-2873.e7 pubmed publisher
O Neill A, Kindberg A, Niethamer T, Larson A, Ho H, Greenberg M, et al. Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. J Cell Biol. 2016;215:217-229 pubmed
Mimche P, Brady L, Keeton S, Fenne D, King T, Quicke K, et al. Expression of the Receptor Tyrosine Kinase EphB2 on Dendritic Cells Is Modulated by Toll-Like Receptor Ligation but Is Not Required for T Cell Activation. PLoS ONE. 2015;10:e0138835 pubmed publisher
Zhang G, Brady J, Liang W, Wu Y, Henkemeyer M, Yan M. EphB4 forward signalling regulates lymphatic valve development. Nat Commun. 2015;6:6625 pubmed publisher
Soskis M, Ho H, Bloodgood B, Robichaux M, Malik A, Ataman B, et al. A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development. Nat Neurosci. 2012;15:1645-54 pubmed publisher
Yu L, Zhou X, Yu J, Huang H, Jiang L, Zhang F, et al. PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs. PLoS ONE. 2012;7:e40930 pubmed publisher
Kawano H, Katayama Y, Minagawa K, Shimoyama M, Henkemeyer M, Matsui T. A novel feedback mechanism by Ephrin-B1/B2 in T-cell activation involves a concentration-dependent switch from costimulation to inhibition. Eur J Immunol. 2012;42:1562-72 pubmed publisher
Dai J, Dalal J, Thakar S, Henkemeyer M, Lemmon V, Harunaga J, et al. EphB regulates L1 phosphorylation during retinocollicular mapping. Mol Cell Neurosci. 2012;50:201-10 pubmed publisher
Maddigan A, Truitt L, Arsenault R, Freywald T, Allonby O, Dean J, et al. EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes. J Immunol. 2011;187:5983-94 pubmed publisher
Pittman A, Gaynes J, Chien C. nev (cyfip2) is required for retinal lamination and axon guidance in the zebrafish retinotectal system. Dev Biol. 2010;344:784-94 pubmed publisher
Afshari F, Kwok J, Fawcett J. Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signaling. J Neurosci. 2010;30:4246-55 pubmed publisher
Mellott D, Burke R. Divergent roles for Eph and ephrin in avian cranial neural crest. BMC Dev Biol. 2008;8:56 pubmed publisher
Liu Z, Conroy W, Stawicki T, Nai Q, Neff R, Berg D. EphB receptors co-distribute with a nicotinic receptor subtype and regulate nicotinic downstream signaling in neurons. Mol Cell Neurosci. 2008;38:236-44 pubmed publisher
Lim B, Matsuda N, Poo M. Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo. Nat Neurosci. 2008;11:160-9 pubmed publisher
Nestor M, Mok L, Tulapurkar M, Thompson S. Plasticity of neuron-glial interactions mediated by astrocytic EphARs. J Neurosci. 2007;27:12817-28 pubmed
Ricard J, Salinas J, Garcia L, Liebl D. EphrinB3 regulates cell proliferation and survival in adult neurogenesis. Mol Cell Neurosci. 2006;31:713-22 pubmed
Ogawa K, Wada H, Okada N, Harada I, Nakajima T, Pasquale E, et al. EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases. J Cell Sci. 2006;119:559-70 pubmed
Nakada M, Niska J, Tran N, McDonough W, Berens M. EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion. Am J Pathol. 2005;167:565-76 pubmed
Wang Y, Ying G, Liu X, Wang W, Dong J, Ni Z, et al. Induction of ephrin-B1 and EphB receptors during denervation-induced plasticity in the adult mouse hippocampus. Eur J Neurosci. 2005;21:2336-46 pubmed
Nakada M, Niska J, Miyamori H, McDonough W, Wu J, Sato H, et al. The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells. Cancer Res. 2004;64:3179-85 pubmed
Davy A, Aubin J, Soriano P. Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 2004;18:572-83 pubmed
Sharfe N, Freywald A, Toro A, Dadi H, Roifman C. Ephrin stimulation modulates T cell chemotaxis. Eur J Immunol. 2002;32:3745-55 pubmed
Murai K, Nguyen L, Irie F, Yamaguchi Y, Pasquale E. Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling. Nat Neurosci. 2003;6:153-60 pubmed

product information

brand :

R&D Systems

master code :

473-EB

SKU :

473-EB-200

product name :

Recombinant Mouse Ephrin-B1 Fc Chimera Protein, CF

unit size :

200 ug

description :

Stretch-activated calcium channel blocker; calcium-sensing receptor agonist

target :

Ephrin-B1

category :

Proteins and Enzymes

alt names :

Cek5-L, EFL3, EFL-3, EFNB1, ELK ligand, Elk-L, ephrin-B1, EphrinB1, LERK-2, STRA-1

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

all available conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

60 kDa, reducing conditions

theoretical molecular weight :

49.2 kDa (monomer)

gene symbol :

Efnb1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse EphB3 Fc Chimera at 2 µg/mL (100 µL/well) can bind Recombinant Mouse Ephrin-B1 Fc Chimera with a linear range of 0.01-0.5 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAA53231

applications :

Binding Activity

source :

NS0-derived Recombinant Mouse Ephrin-B1 Fc Chimera Protein, CF

USD :

289

Jul-22 :

313 USD

sizes available :

200 ug

more info or order :

R&D Systems product webpage