Recombinant Human Semaphorin 4A Fc Chimera Protein, CF | R&D Systems 4694-S4-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Semaphorin 4A Fc Chimera Protein, CF

catalog :

4694-S4-050

quantity :

50 ug

price :

423 USD

citations: 2

Reference
Delgoffe G, Woo S, Turnis M, Gravano D, Guy C, Overacre A, et al. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature. 2013;501:252-6 pubmed publisher
Meda C, Molla F, De Pizzol M, Regano D, Maione F, Capano S, et al. Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages. J Immunol. 2012;188:4081-92 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

4694-S4

SKU :

4694-S4-050

product name :

Recombinant Human Semaphorin 4A Fc Chimera Protein, CF

Description :

The Recombinant Human Semaphorin 4A Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Semaphorin 4A Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Semaphorin 4A

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS and Tween® 20.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

105-120 kDa, reducing conditions

theoretical molecular weight :

98.5 kDa (monomer)

gene symbol :

SEMA4A

details of functionality :

Measured by its ability to cause collapse of chick embryonic dorsal root ganglia (DRG) neuron growth cones. 2.5-5.0 µg/mL of Recombinant Human Semaphorin 4A Fc Chimera causes 50% growth cone collapse in the presence of 10 ng/mL of Recombinant Human beta-NGF (Catalog # 256-GF ). Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9H3S1

applications :

Bioactivity

source :

NS0-derived Recombinant Human Semaphorin 4A Fc Chimera Protein

USD :

423 USD

alt names :

CORD10, RP35, Sema B, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4A, SEMA4A, SEMAB, semaphorin-4A, Semaphorin-B, SemB, SEMBFLJ12287

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.