Recombinant Mouse VEGF-D Protein | R&D Systems 469-VD-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse VEGF-D Protein

catalog :

469-VD-025

quantity :

25 ug

price :

432 USD

citations: 6

Reference
Schlüter A, Aksan B, Diem R, Fairless R, Mauceri D. VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic Injury. Mol Ther Methods Clin Dev. 2020;17:281-299 pubmed publisher
López Bellido R, Puig S, Huang P, Tsai C, Turner H, Galko M, et al. Growth factor signaling regulates mechanical nociception in flies and vertebrates. J Neurosci. 2019;: pubmed publisher
Litke C, Bading H, Mauceri D. Histone deacetylase 4 shapes neuronal morphology via a mechanism involving regulation of expression of vascular endothelial growth factor D. J Biol Chem. 2018;293:8196-8207 pubmed publisher
Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFÎ² signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed publisher
Takayanagi S, Hiroyama T, Yamazaki S, Nakajima T, Morita Y, Usui J, et al. Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain. Blood. 2006;107:4317-25 pubmed
Hamaguchi I, Morisada T, Azuma M, Murakami K, Kuramitsu M, Mizukami T, et al. Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival. Blood. 2006;107:1207-13 pubmed

product information

master code :

469-VD

SKU :

469-VD-025

product name :

Recombinant Mouse VEGF-D Protein

unit size :

25 ug

description :

The Recombinant Mouse VEGF-D Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse VEGF-D Protein has been validated for the following applications: Bioactivity, Binding Activity.

target :

VEGF-D

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

14-20 kDa, reducing conditions

theoretical molecular weight :

13 kDa

gene symbol :

Figf

details of functionality :

Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. Marconcini, L. et al . (1999) Proc. Natl. Acad. Sci. USA 96 :9671. The ED50 for this effect is 0.2-0.8á╡g/mL. Measured by its binding ability in a functional ELISA. Immobilized rmFlt-4/Fc Chimera at 5 ╡g/mL (100á╡L/well) can bind rmVEGF-D with an apparent KDá á50ánM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P97946

applications :

Bioactivity, Binding Activity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse VEGF-D protein Phe98-Ser206, with a C-terminal 6-His tag

source short :

Sf 21 (baculovirus)

USD :

432 USD

alt names :

c-fos induced growth factor (vascular endothelial growth factor D), FIGF, vascular endothelial growth factor D, VEGFD, VEGF-DVEGFDc-Fos-induced growth factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.