This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse FGF acidic/FGF1 Protein
catalog :
4686-FA-025
quantity :
25 ug
price :
240 USD
citations: 11
Reference
Xu Y, Alves Wagner A, Inada H, Firouzjah S, Osana S, Amir M, et al. Placenta-derived SOD3 deletion impairs maternal behavior via alterations in FGF/FGFR-prolactin signaling axis. Cell Rep. 2024;43:114789 pubmed publisher
Heitman K, Bollenbecker S, Bradley J, Czaya B, Fajol A, Thomas S, et al. Hyperphosphatemia Contributes to Skeletal Muscle Atrophy in Mice. Int J Mol Sci. 2024;25: pubmed publisher
Patel V, Aure M, Choi S, Ball J, Lane E, Wang Z, et al. Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024;15:7584 pubmed publisher
Pei F, Ma L, Jing J, Feng J, Yuan Y, Guo T, et al. Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis. Nat Commun. 2023;14:344 pubmed publisher
Ichikawa K, Watanabe Miyano S, Minoshima Y, Matsui J, Funahashi Y. Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy. Sci Rep. 2020;10:2939 pubmed publisher
Kang J, Choi Y, Seo B, Jo U, Park S, Kim Y, et al. A Selective FGFR inhibitor AZD4547 suppresses RANKL/M-CSF/OPG-dependent ostoclastogenesis and breast cancer growth in the metastatic bone microenvironment. Sci Rep. 2019;9:8726 pubmed publisher
Taguchi A, Nishinakamura R. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:730-746.e6 pubmed publisher
Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G. The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-? signaling. Dev Biol. 2013;377:415-27 pubmed publisher
Kharitonenkov A, Beals J, Micanovic R, Strifler B, Rathnachalam R, Wroblewski V, et al. Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319. PLoS ONE. 2013;8:e58575 pubmed publisher
Tucker B, Anfinson K, Mullins R, Stone E, Young M. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med. 2013;2:16-24 pubmed publisher
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008;283:23139-49 pubmed publisher
product information
master code :
4686-FA
SKU :
4686-FA-025
product name :
Recombinant Mouse FGF acidic/FGF1 Protein
unit size :
25 ug
description :
The Recombinant Mouse FGF acidic/FGF1 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse FGF acidic/FGF1 Protein has been validated for the following applications: Bioactivity.
target :
FGF acidic/FGF1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in MOPS, Na2SO4, EDTA and DTT with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
theoretical molecular weight :
16 kDa
gene symbol :
Fgf1
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.05-0.25 ng/mL in the presence of 10á╡g/mL heparin.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_034327
applications :
Bioactivity
source long :
E. coli -derived mouse FGF acidic/FGF1 protein Phe16-Asp155, with an N-terminal Met
source short :
E. coli
USD :
240 USD
alt names :
AFGF, alpha, alpha-ECGF, beta-ECGF, ECGF, ECGFB, ECGF-betaAcidic fibroblast growth factor, endothelial cell growth factor, beta, FGF acidic, FGF-1, FGFABeta-endothelial cell growth factor, FGF-alpha, fibroblast growth factor 1 (acidic), GLIO703, HBGF1, HBGF-1, heparin-binding growth factor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.