product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse FGF acidic/FGF1 Protein, CF
catalog :
4686-FA-025/CF
quantity :
25 ug
price :
219 USD
more info or order :
citations: 5
Reference
Ichikawa K, Watanabe Miyano S, Minoshima Y, Matsui J, Funahashi Y. Activated FGF2 signaling pathway in tumor vasculature is essential for acquired resistance to anti-VEGF therapy. Sci Rep. 2020;10:2939 pubmed publisher
Kang J, Choi Y, Seo B, Jo U, Park S, Kim Y, et al. A Selective FGFR inhibitor AZD4547 suppresses RANKL/M-CSF/OPG-dependent ostoclastogenesis and breast cancer growth in the metastatic bone microenvironment. Sci Rep. 2019;9:8726 pubmed publisher
Taguchi A, Nishinakamura R. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:730-746.e6 pubmed publisher
Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G. The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-? signaling. Dev Biol. 2013;377:415-27 pubmed publisher
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008;283:23139-49 pubmed publisher
product information
brand :
R&D Systems
master code :
4686-FA/CF
SKU :
4686-FA-025/CF
product name :
Recombinant Mouse FGF acidic/FGF1 Protein, CF
description :
The Recombinant Mouse FGF acidic/FGF1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse FGF acidic/FGF1 Protein, CF has been validated for the following applications: Bioactivity.
target :
FGF acidic/FGF1
category :
Proteins and Enzymes
sizes available :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4, EDTA and DTT.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
theoretical molecular weight :
16 kDa
gene symbol :
Fgf1
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.05-0.25 ng/mL in the presence of 10 µg/mL heparin.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_034327
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse FGF acidic/FGF1 Protein, CF
USD :
215
USD 2023 :
219 USD
alt names :
AFGF, alpha, alpha-ECGF, beta-ECGF, ECGF, ECGFB, ECGF-betaAcidic fibroblast growth factor, endothelial cell growth factor, beta, FGF acidic, FGF-1, FGFABeta-endothelial cell growth factor, FGF-alpha, fibroblast growth factor 1 (acidic), GLIO703, HBGF1, HBGF-1, heparin-binding growth factor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.