product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD47 Fc Chimera Protein, CF
catalog :
4670-CD-050
quantity :
50 ug
price :
434 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Jung C, Ménoret S, Brusselle L, Tesson L, Usal C, Chenouard V, et al. Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats. Sci Rep. 2016;6:31455 pubmed publisher
Sun F, Zhang C, Chen X, Wei Y, Li S, Liu S, et al. Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. J Neuroinflammation. 2016;13:85 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
4670-CD
SKU :
4670-CD-050
product name :
Recombinant Human CD47 Fc Chimera Protein, CF
Description :
The Recombinant Human CD47 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD47 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CD47
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
60-65 kDa, reducing conditions
theoretical molecular weight :
40.3 kDa (monomer)
gene symbol :
CD47
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human (rh) SIRP alpha/CD172a Fc Chimera (Catalog # 4546-SA ) is coated at 2 µg/mL, Recombinant Human CD47 Fc Chimera binds with an apparent Kd 1 nM. Optimal dilutions should be determined by each laboratory for each application. Also measured by its ability to antagonize red blood cell adhesion to immobilized rhSIRP alpha Fc Chimera. The ED50 for this effect is 0.5-2.0 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q08722
applications :
Bioactivity
source :
NS0-derived Recombinant Human CD47 Fc Chimera Protein
USD :
434 USD
alt names :
antigen identified by monoclonal 1D8, Antigenic surface determinant protein OA3, CD47, CD47 antigen, CD47 antigen (Rh-related antigen, integrin-associated signal transducer), CD47 glycoprotein, CD47 molecule, IAP, IAPintegrin associated protein, Integrin-associated protein, leukocyte surface antigen CD47, MER6, MER6integrin-associated signal transducer, OA3, Protein MER6, Rh-related antigen
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.