Recombinant Human PARP Enzyme (HSA) | R&D Systems 4668-01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

ELISA/assay

product name :

Recombinant Human PARP Enzyme (HSA)

catalog :

4668-01

quantity :

1000 UN

price :

269 USD

citations: 12

Reference
Talhaoui I, Lebedeva N, Zarkovic G, Saint Pierre C, Kutuzov M, Sukhanova M, et al. Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro. Nucleic Acids Res. 2016;44:9279-9295 pubmed
Silva A, Ryan D, Galanty Y, Low J, Vandevenne M, Jackson S, et al. The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose). J Biol Chem. 2016;291:924-38 pubmed publisher
Khadka P, Hsu J, Veith S, Tadokoro T, Shamanna R, Mangerich A, et al. Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities. Mol Cell Biol. 2015;35:3974-89 pubmed publisher
Wu Z, Wang C, Bai M, Li X, Mei Q, Li X, et al. An LRP16-containing preassembly complex contributes to NF-ÎºB activation induced by DNA double-strand breaks. Nucleic Acids Res. 2015;43:3167-79 pubmed publisher
Li N, Zhang Y, Han X, Liang K, Wang J, Feng L, et al. Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth. Genes Dev. 2015;29:157-70 pubmed publisher
Khoury Haddad H, Guttmann Raviv N, Ipenberg I, Huggins D, Jeyasekharan A, Ayoub N. PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair. Proc Natl Acad Sci U S A. 2014;111:E728-37 pubmed publisher
Dutt S, Wilch C, Gersthagen T, Talbiersky P, Bravo Rodriguez K, Hanni M, et al. Molecular tweezers with varying anions: a comparative study. J Org Chem. 2013;78:6721-34 pubmed publisher
MacPherson L, Tamblyn L, Rajendra S, Bralha F, McPherson J, Matthews J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation. Nucleic Acids Res. 2013;41:1604-21 pubmed publisher
Gottschalk A, Trivedi R, Conaway J, Conaway R. Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate. J Biol Chem. 2012;287:43527-32 pubmed publisher
King B, Cooper K, Liu K, Hudson L. Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair. J Biol Chem. 2012;287:39824-33 pubmed publisher
Wright R, Castellano G, Bonet J, Le Dily F, Font Mateu J, Ballaré C, et al. CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells. Genes Dev. 2012;26:1972-83 pubmed publisher
Narwal M, Fallarero A, Vuorela P, Lehtiö L. Homogeneous screening assay for human tankyrase. J Biomol Screen. 2012;17:593-604 pubmed publisher

product information

brand :

R&D Systems

SKU :

4668-01

product name :

Recombinant Human PARP Enzyme (HSA)

unit sizes :

1000 UN

target :

PARP

category :

Activity Assays

species :

Multi-Species

catalog number base :

4668-100-01

USD :

269 USD

alt names :

ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADPRT, ADPRT 1, ADPRTADP-ribosyltransferase NAD(+), EC 2.4.2, EC 2.4.2.30, NAD(+) ADP-ribosyltransferase 1, PARP apoptosis, PARP1, PARP-1, PARPADPRT1, poly (ADP-ribose) polymerase 1, poly (ADP-ribose) polymerase family, member 1, poly [ADP-ribose] polymerase 1, poly(ADP-ribose) polymerase, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, Poly[ADP-ribose] synthase 1, PPOL, PPOLpADPRT-1

storage :

Store at -20 °C in a manual defrost freezer. For long-term storage, freeze in working aliquots at -80 °C. Avoid freeze-thaw cycles.