This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-28A/IFN-lambda 2 Protein
catalog :
4635-ML
quantity :
25 ug
price :
339 USD
citations: 5
Reference
Liou A, Liao C, Chou S, Chang Y, Chang C, Shih C. Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model. J Biomed Sci. 2019;26:93 pubmed publisher
Nguyen T, Smith B, Elgass K, Creed S, Cheung S, Tate M, et al. SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm. J Immunol. 2019;: pubmed publisher
Stier M, Goleniewska K, Cephus J, Newcomb D, Sherrill T, Boyd K, et al. STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection. J Immunol. 2017;199:510-519 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J Virol. 2010;84:12703-12 pubmed publisher
product information
brand :
R&D Systems
master code :
4635-ML
SKU :
4635-ML-025
product name :
Recombinant Mouse IL-28A/IFN-lambda 2 Protein
description :
The Recombinant Mouse IL-28A/IFN-lambda 2 Protein from R&D Systems is derived from NS0. The Recombinant Mouse IL-28A/IFN-lambda 2 Protein has been validated for the following applications: Bioactivity.
target :
IL-28A/IFN-lambda 2
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
25 kDa and 30 kDa, reducing conditions
theoretical molecular weight :
20.5 kDa
details of functionality :
Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al . (2003) Nat. Immunol. 4 :63. The ED50 for this effect is 0.75-3.75 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
4635-ML
accessionNumbers :
NP_001019844
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived mouse IL-28A/IFN-lambda 2 protein Asp20-Val193, with a C-terminal 6-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
interleukin-28A, IFN-lambda 2, IL28A, IL-28A, interferon, lambda 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.