product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CCL9/10/MIP-1 gamma Protein
catalog :
463-MG-025
quantity :
25 ug
price :
377 USD
more info or order :
citations: 4
Reference
Li L, Ni L, Heary R, Elkabes S. Astroglial TLR9 antagonism promotes chemotaxis and alternative activation of macrophages via modulation of astrocyte-derived signals: implications for spinal cord injury. J Neuroinflammation. 2020;17:73 pubmed publisher
Sharif S, Ueda N, Nakatani Y, Wise L, Clifton S, Lateef Z, et al. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity. Front Microbiol. 2019;10:1421 pubmed publisher
Binder N, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig T, et al. Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. Nat Med. 2009;15:417-24 pubmed publisher
Okamatsu Y, Kim D, Battaglino R, Sasaki H, Späte U, Stashenko P. MIP-1 gamma promotes receptor-activator-of-NF-kappa-B-ligand-induced osteoclast formation and survival. J Immunol. 2004;173:2084-90 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
463-MG
SKU :
463-MG-025
product name :
Recombinant Mouse CCL9/10/MIP-1 gamma Protein
Description :
The Recombinant Mouse CCL9/10/MIP-1 gamma Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CCL9/10/MIP-1 gamma Protein has been validated for the following applications: Bioactivity.
target :
CCL9/10/MIP-1 gamma
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
theoretical molecular weight :
11.5 kDa
gene symbol :
Ccl9
details of functionality :
Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. The ED50 for this effect is 0.2-0.6 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR1. The ED50 for this effect is 0.002-0.01 µg/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q3U9T8
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse CCL9/10/MIP-1 gamma Protein
USD :
377 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.