Recombinant Human Prostasin/Prss8 Protein, CF | R&D Systems 4599-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Prostasin/Prss8 Protein, CF

catalog :

4599-SE-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Szabo R, Uzzun Sales K, Kosa P, Shylo N, Godiksen S, Hansen K, et al. Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation. PLoS Genet. 2012;8:e1002937 pubmed publisher
Sales K, Masedunskas A, Bey A, Rasmussen A, Weigert R, List K, et al. Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome. Nat Genet. 2010;42:676-83 pubmed publisher

product information

master code :

4599-SE

SKU :

4599-SE-010

product name :

Recombinant Human Prostasin/Prss8 Protein, CF

unit size :

10 ug

description :

The Recombinant Human Prostasin/Prss8 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Prostasin/Prss8 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Prostasin/Prss8

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and CaCl2.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

39 kDa, reducing conditions

theoretical molecular weight :

32 kDa (Pro) 31 kDa (Mature)

gene symbol :

PRSS8

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate Boc-QAR-AMC (Catalog # ES014 ). The specific activity is 10 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_002764

applications :

Enzyme Activity

source long :

Chinese Hamster Ovary cell line, CHO-derived human Prostasin/Prss8 protein Ala33-Gly319, with a C-terminal 10-His tag The pro form was activated and further purified.

source short :

CHO

USD :

432 USD

alt names :

CAP1, channel-activating protease 1, EC 3.4.21, EC 3.4.21.-, EC 3.4.21.120, prostasin, protease, serine, 8, Prss8, Serine protease 8

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage