Recombinant Mouse CCL7/MARC Protein | R&D Systems 456-MC-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CCL7/MARC Protein

catalog :

456-MC-010

quantity :

10 ug (also 50 ug)

price :

336 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Broquet A, Gourain V, Goronflot T, Le Mabecque V, Sinha D, Ashayeripanah M, et al. Sepsis-trained macrophages promote antitumoral tissue-resident T cells. Nat Immunol. 2024;25:802-819 pubmed publisher
Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, et al. Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function. PLoS ONE. 2023;18:e0280590 pubmed publisher
Popiolek Barczyk K, Ciechanowska A, Ciapała K, Pawlik K, Oggioni M, Mercurio D, et al. The CCL2/CCL7/CCL12/CCR2 pathway is substantially and persistently upregulated in mice after traumatic brain injury, and CCL2 modulates the complement system in microglia. Mol Cell Probes. 2020;54:101671 pubmed publisher
Gomez Lopez N, Arenas Hernandez M, Romero R, Miller D, Garcia Flores V, Leng Y, et al. Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes. Cell Rep. 2020;32:107874 pubmed publisher
Kwiatkowski K, Popiolek Barczyk K, Piotrowska A, Rojewska E, Ciapała K, Makuch W, et al. Chemokines CCL2 and CCL7, but not CCL12, play a significant role in the development of pain-related behavior and opioid-induced analgesia. Cytokine. 2019;119:202-213 pubmed publisher
Kuo C, Collins A, Boettner D, Yang Y, Ono S. Role of CCL7 in Type I Hypersensitivity Reactions in Murine Experimental Allergic Conjunctivitis. J Immunol. 2017;198:645-656 pubmed publisher
Fan Q, Gu D, Liu H, Yang L, Zhang X, Yoder M, et al. Defective TGF-? signaling in bone marrow-derived cells prevents hedgehog-induced skin tumors. Cancer Res. 2014;74:471-483 pubmed publisher
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed
Carrillo A, Monreal Y, Ramirez P, Marin L, Parrilla P, Oliver F, et al. Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells. Nucleic Acids Res. 2004;32:757-66 pubmed

product information

brand :

R&D Systems

master code :

456-MC

SKU :

456-MC-010

product name :

Recombinant Mouse CCL7/MARC Protein

unit size :

10 ug (also 50 ug)

seo description :

The Recombinant Mouse CCL7/MARC Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CCL7/MARC Protein has been validated for the following applications: Bioactivity.

target :

CCL7/MCP-3/MARC

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

8.5 kDa

gene symbol :

Ccl7

details of functionality :

Measured by its ability to chemoattract 2-day cultured human monocytes. Matsushima,áK. etáal . (1989) J.áExp. Med. 169 :1485. The ED50 for this effect is 0.1-0.3 ╡g/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR2A. The ED50 for this effect is 0.5-2á╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q03366.1

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse CCL7/MARC Protein

USD :

336 USD

alt names :

C-C motif chemokine 7, chemokine (C-C motif) ligand 7, FIC, MARC, MCP-3, MCP3Monocyte chemotactic protein 3, MCP-3Small-inducible cytokine A7, MGC138465, Monocyte chemoattractant protein 3, NC28SCYA6, SCYA7MGC138463, small inducible cytokine A7 (monocyte chemotactic protein 3)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage