protein

Recombinant Human SIRP alpha/CD172a Fc Chimera Protein, CF

4546-SA-050

50 ug

458 USD

4546-SA

4546-SA-050

Recombinant Human SIRP alpha/CD172a Fc Chimera Protein, CF

The Recombinant Human SIRP alpha/CD172a Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human SIRP alpha/CD172a Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

SIRP alpha/CD172a

Proteins and Enzymes

50 ug

Lyophilized from a 0.2 µm filtered solution in PBS.

Unconjugated

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Human

70-105 kDa, reducing conditions

64 kDa (monomer)

SIRPA

Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Subramanian, S. et al . (2006) Blood 107 :2548. Red blood cells, added at 10 x 106 cells/mL (100 µL/well) to SIRP alpha coated plates, will adhere after 1 hour at 37° C. The ED50 for this effect is 0.6-2.4 µg/mL. Optimal dilutions should be determined by each laboratory for each application.

<0.10 EU per 1 µg of the protein by the LAL method.

NP_542970.1

Bioactivity

CHO-derived Recombinant Human SIRP alpha/CD172a Fc Chimera Protein

458 USD

Bit, BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a, CD172a antigen, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MFR, MFRtyrosine phosphatase SHP substrate 1, MYD1, MYD-1, MyD-1 antigen, P84, protein tyrosine phosphatase, non-receptor type substrate 1, PTPNS1, SHP substrate 1, SHPS1, SHPS-1, SHPS1CD172A, signal-regulatory protein alpha, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRPA, SIRPalpha, SIRP-ALPHA-1, Sirp-alpha-2, SIRPalpha2, Sirp-alpha-3, SIRPtyrosine-protein phosphatase non-receptor type substrate 1

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.