product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PEAR1 Protein, CF
catalog :
4527-PR-050
quantity :
50 ug
price :
498 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Kauskot A, Di Michele M, Loyen S, Freson K, Verhamme P, Hoylaerts M. A novel mechanism of sustained platelet ?IIb?3 activation via PEAR1. Blood. 2012;119:4056-65 pubmed publisher
Faraday N, Yanek L, Yang X, Mathias R, Herrera Galeano J, Suktitipat B, et al. Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood. 2011;118:3367-75 pubmed publisher
product information
master code :
4527-PR
SKU :
4527-PR-050
product name :
Recombinant Human PEAR1 Protein, CF
unit size :
50 ug
description :
The Recombinant Human PEAR1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human PEAR1 Protein, CF has been validated for the following applications: Bioactivity.
target :
PEAR1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
120-130 kDa, reducing conditions
theoretical molecular weight :
78.3 kDa
gene symbol :
PEAR1
details of functionality :
Measured by its binding ability in a functional ELISA. Recombinant Human PEAR1 (Catalog # 4527-PR) binds Recombinant Human Fc epsilon RI alpha (Catalog # 6678-FC ) with an ED50 of 0.0400-0.340 ╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_001073940
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human PEAR1 protein Leu21-Ser754 with a C-terminal 6-His tag
source short :
CHO
USD :
498 USD
alt names :
JEDI, platelet endothelial aggregation receptor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.