Recombinant Mouse CCL4/MIP-1 beta Protein | R&D Systems 451-MB-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CCL4/MIP-1 beta Protein

catalog :

451-MB-010

quantity :

10 ug (also 50 ug)

price :

300 USD

citations: 11

Reference
Anastasaki C, Mo J, Chen J, Chatterjee J, Pan Y, Scheaffer S, et al. Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1. Nat Commun. 2022;13:2785 pubmed publisher
Chatterjee J, Sanapala S, Cobb O, Bewley A, Goldstein A, Cordell E, et al. Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia. Nat Commun. 2021;12:7122 pubmed publisher
Chen X, He Y, Wei Q, Wang C. Basil Polysaccharide Reverses Development of Experimental Model of Sepsis-Induced Secondary Staphylococcus aureus Pneumonia. Mediators Inflamm. 2021;2021:5596339 pubmed publisher
Guo X, Pan Y, Xiong M, Sanapala S, Anastasaki C, Cobb O, et al. Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth. Nat Commun. 2020;11:2177 pubmed publisher
Jo M, Kim J, Song G, Seo M, Hwang E, Suk K. Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation. J Neurosci. 2017;37:2878-2894 pubmed publisher
Sato S, Zhang X. The Friend leukaemia virus integration 1 (Fli-1) transcription factor affects lupus nephritis development by regulating inflammatory cell infiltration into the kidney. Clin Exp Immunol. 2014;177:102-9 pubmed publisher
Fujihara Y, Takato T, Hoshi K. Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regeneration. Stem Cells. 2014;32:1208-19 pubmed publisher
Shojaei F, Wu X, ZHONG C, Yu L, Liang X, Yao J, et al. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature. 2007;450:825-31 pubmed
Tavares E, Minano F. Differential sensitivities of pyrogenic chemokine fevers to CC chemokine receptor 5 antibodies. Fundam Clin Pharmacol. 2004;18:163-9 pubmed
Menten P, Saccani A, Dillen C, Wuyts A, Struyf S, Proost P, et al. Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma. J Leukoc Biol. 2002;72:780-9 pubmed
Bless N, Huber Lang M, Guo R, Warner R, Schmal H, Czermak B, et al. Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats. J Immunol. 2000;164:2650-9 pubmed

product information

master code :

451-MB

SKU :

451-MB-010

product name :

Recombinant Mouse CCL4/MIP-1 beta Protein

unit size :

10 ug (also 50 ug)

description :

The Recombinant Mouse CCL4/MIP-1 beta Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CCL4/MIP-1 beta Protein has been validated for the following applications: Bioactivity.

target :

CCL4/MIP-1 beta

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

7.8 kDa

gene symbol :

Ccl4

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. The ED50 for this effect is 2.50-25.0 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q5QNV9

applications :

Bioactivity

source long :

E. coli -derived mouse CCL4/MIP-1 beta protein Ala24-Asn92

source short :

E. coli

USD :

300 USD

alt names :

ACT2, ACT-2, AT744.1, C-C motif chemokine 4, chemokine (C-C motif) ligand 4, Exodus-3, G-26, G-26 T-lymphocyte-secreted protein, HC21, LAG1, LAG-1, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, MIP1 beta, MIP-1 beta, MIP1B, MIP1B1, MIP-1-beta, MIP-1-beta(1-69), PAT 744, Protein H400, SCYA2, SCYA4, secreted protein G-26, SIS-gamma, small inducible cytokine A4 (homologous to mouse Mip-1b), Small-inducible cytokine A4, T-cell activation protein 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.