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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CCL3/MIP-1 alpha Protein, CF
catalog :
450-MA-010/CF
quantity :
10 ug (also 50 ug)
price :
340 USD
more info or order :
citations: 31
Reference |
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Wu Y, Li Y, Matsushima K, Baba T, Mukaida N. CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process. J Immunol. 2008;181:6384-93 pubmed
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Shojaei F, Wu X, ZHONG C, Yu L, Liang X, Yao J, et al. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature. 2007;450:825-31 pubmed
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Penido C, Costa M, Souza M, Costa K, Candea A, Benjamim C, et al. Involvement of CC chemokines in gammadelta T lymphocyte trafficking during allergic inflammation: the role of CCL2/CCR2 pathway. Int Immunol. 2008;20:129-39 pubmed
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Zozulya A, Reinke E, Baiu D, Karman J, Sandor M, Fabry Z. Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases. J Immunol. 2007;178:520-9 pubmed
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Ramos C, Fernandes K, Canetti C, Teixeira M, Silva J, Cunha F. Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4). Eur J Immunol. 2006;36:2025-34 pubmed
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Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, et al. Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation. Biochem Biophys Res Commun. 2006;345:1122-30 pubmed
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Ellaban E, Bolgos G, Remick D. Selective macrophage suppression during sepsis. Cell Immunol. 2004;231:103-11 pubmed
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Perrin F, Lacroix S, Avilés Trigueros M, David S. Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. Brain. 2005;128:854-66 pubmed
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Speyer C, Gao H, Rancilio N, Neff T, Huffnagle G, Sarma J, et al. Novel chemokine responsiveness and mobilization of neutrophils during sepsis. Am J Pathol. 2004;165:2187-96 pubmed
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Reading P, Symons J, Smith G. A soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection. J Immunol. 2003;170:1435-42 pubmed
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Menten P, Saccani A, Dillen C, Wuyts A, Struyf S, Proost P, et al. Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma. J Leukoc Biol. 2002;72:780-9 pubmed
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product information
brand :
R&D Systems
master code :
450-MA/CF
SKU :
450-MA-010/CF
product name :
Recombinant Mouse CCL3/MIP-1 alpha Protein, CF
description :
The Recombinant Mouse CCL3/MIP-1 alpha Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CCL3/MIP-1 alpha Protein, CF has been validated for the following applications: Bioactivity.
target :
CCL3/MIP-1 alpha
category :
Proteins and Enzymes
unit sizes :
10 ug (also 50 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
theoretical molecular weight :
7.8 kDa
gene symbol :
CCL3
details of functionality :
Measured by its ability to chemoattract 2-day cultured human monocytes. The ED50 for this effect is 5-25 ng/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. The ED50 for this effect is 0.4-2.0 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q5QNW0
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse CCL3/MIP-1 alpha Protein, CF
USD :
340 USD
alt names :
C-C motif chemokine 3, MIP1-(a), AI323804, chemokine (C-C motif) ligand 3, G0S19-1, LD78a, LD78alpha, MIP1 alpha, MIP-1 alpha, Mip1a, MIP-1alpha, MIP1-alpha, PAT 464.1, SCYA3, SIS-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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