Recombinant Human Thrombopoietin R Protein, CF | R&D Systems 4444-TR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Thrombopoietin R Protein, CF

catalog :

4444-TR

quantity :

50 ug

price :

339 USD

citations: 2

Reference
Yang Z, Du M, Wang W, Xin X, Ma P, Zhang H, et al. Affinity maturation of an TpoR targeting antibody in full-length IgG form for enhanced agonist activity. Protein Eng Des Sel. 2018;31:233-241 pubmed publisher
Lupia E, Bosco O, Goffi A, Poletto C, Locatelli S, Spatola T, et al. Thrombopoietin contributes to enhanced platelet activation in cigarette smokers. Atherosclerosis. 2010;210:314-9 pubmed publisher

product information

brand :

R&D Systems

master code :

4444-TR

SKU :

4444-TR-050

product name :

Recombinant Human Thrombopoietin R Protein, CF

description :

The Recombinant Human Thrombopoietin R Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Thrombopoietin R Protein, CF has been validated for the following applications: Bioactivity.

target :

Thrombopoietin R/Tpo R

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

56-76 kDa, reducing conditions

theoretical molecular weight :

53.4 kDa

gene symbol :

MPL

details of functionality :

Measured by its ability to inhibit the Tpo-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 1-5 µg/mL in the presence of 7.5 ng/mL of rhTpo (Catalog # 288-TP).

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

4444-TR

accessionNumbers :

P40238

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human Thrombopoietin R/Tpo R protein Ser25-Trp491, with a C-terminal 6-His tag

2020 USD :

339

2021 USD :

339 USD

alt names :

CD110, CD110 antigen, C-MPL, MPL, MPLV, Myeloproliferative leukemia protein, myeloproliferative leukemia virus oncogene, Proto-oncogene c-Mpl, thrombopoietin receptor, TpoR, TPO-R, TPORMPLV

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.