Recombinant Mouse BMPR-IB/ALK-6 Fc Chimera (NS0) Protein, CF | R&D Systems 444-BNS-100/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse BMPR-IB/ALK-6 Fc Chimera (NS0) Protein, CF

catalog :

444-BNS-100/CF

quantity :

100 ug

price :

529 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Niessen K, Zhang G, Ridgway J, Chen H, Yan M. ALK1 signaling regulates early postnatal lymphatic vessel development. Blood. 2010;115:1654-61 pubmed publisher
Tomoeda M, Yamada S, Shirai H, Ozawa Y, Yanagita M, Murakami S. PLAP-1/asporin inhibits activation of BMP receptor via its leucine-rich repeat motif. Biochem Biophys Res Commun. 2008;371:191-6 pubmed publisher
Close J, Gumuscu B, Reh T. Retinal neurons regulate proliferation of postnatal progenitors and Müller glia in the rat retina via TGF beta signaling. Development. 2005;132:3015-26 pubmed

product information

master code :

444-BNS/CF

SKU :

444-BNS-100/CF

product name :

Recombinant Mouse BMPR-IB/ALK-6 Fc Chimera (NS0) Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse BMPR-IB/ALK-6 Fc Chimera (NS0) Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse BMPR-IB/ALK-6 Fc Chimera (NS0) Protein, CF has been validated for the following applications: Bioactivity.

target :

BMPR-IB/ALK-6

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

55 kDa, reducing conditions

theoretical molecular weight :

40.6 kDa (monomer)

gene symbol :

Bmpr1b

details of functionality :

Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.5-2 ╡g/mL in the presence of 30 ng/mL of rhBMP-4.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P36898

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse BMPR-IB/ALK-6 protein Mouse BMPR-IB (Leu2 - Lys126) Accession # P36898 DIEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

529 USD

alt names :

activin receptor-like kinase 6, ALK-6, ALK6CDw293, BMP type-1B receptor, BMPR1B, BMPR-1B, BMPRIB, bone morphogenetic protein receptor type-1B, bone morphogenetic protein receptor, type IB, CDw293, CDw293 antigen, EC 2.7.11, EC 2.7.11.30, serine/threonine receptor kinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage