product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ADAM12 Protein, CF
catalog :
4416-AD-020
quantity :
20 ug
price :
470 USD
more info or order :
citations: 2
Reference
Kim H, Fu Y, Hong H, Lee S, Lee D, Kim H. Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex. Nat Commun. 2022;13:4434 pubmed publisher
Roy R, Dagher A, Butterfield C, Moses M. ADAM12 Is a Novel Regulator of Tumor Angiogenesis via STAT3 Signaling. Mol Cancer Res. 2017;15:1608-1622 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
4416-AD
SKU :
4416-AD-020
product name :
Recombinant Human ADAM12 Protein, CF
Description :
The Recombinant Human ADAM12 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human ADAM12 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
ADAM12
category :
Proteins and Enzymes
unit size :
20 ug
buffer :
Supplied as a 0.2 µm filtered solution in Sodium Acetate, CaCl2 and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
25-30 kDa, 50-55 kDa 68-72 kDa, reducing conditions
theoretical molecular weight :
55 kDa (Pro) 34 kDa (Mature)
gene symbol :
ADAM12
details of functionality :
Measured by its ability to cleave IGFBP-3.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAC08702
applications :
Enzyme Activity
source :
CHO-derived Recombinant Human ADAM12 Protein
USD :
470 USD
alt names :
a disintegrin and metalloproteinase domain 12 (meltrin alpha), ADAM 12, ADAM metallopeptidase domain 12, disintegrin and metalloproteinase domain-containing protein 12, EC 3.4.24, EC 3.4.24.58, MCMP, MCMPMltna, Meltrin alpha, Meltrin-alpha, MLTNA, MLTNEC 3.4.24.-
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.