product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CCL19/MIP-3 beta Protein, CF
catalog :
440-M3-025/CF
quantity :
25 ug
price :
294 USD
more info or order :
citations: 38
Reference
Storjohann R, Gericke B, Reifenrath J, Herrmann T, Behrens P, Oltmanns H, et al. Influence of PEG Chain Length of Functionalized Magnetic Nanoparticles on the Cytocompatibility and Immune Competence of Primary Murine Macrophages and Dendritic Cells. Int J Mol Sci. 2023;24: pubmed publisher
Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, et al. Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function. PLoS ONE. 2023;18:e0280590 pubmed publisher
Liu J, Cheng Y, Zhang X, Chen Y, Zhu H, Chen K, et al. Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. Cell Rep. 2023;42:111991 pubmed publisher
Wolf E, Howard Z, Duan L, Tam H, Xu Y, Cyster J. GPR174 signals via Gαs to control a CD86-containing gene expression program in B cells. Proc Natl Acad Sci U S A. 2022;119:e2201794119 pubmed publisher
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
Saxena V, Piao W, Li L, Paluskievicz C, Xiong Y, Simon T, et al. Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses. Cell Rep. 2022;39:110727 pubmed publisher
Ming Chin Lee K, Achuthan A, De Souza D, Lupancu T, Binger K, Lee M, et al. Type I interferon antagonism of the JMJD3-IRF4 pathway modulates macrophage activation and polarization. Cell Rep. 2022;39:110719 pubmed publisher
Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed publisher
Niu X, Sang H, Wang J. Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration. J Nutr Biochem. 2021;89:108560 pubmed publisher
Renkawitz J, Kopf A, Stopp J, de Vries I, Driscoll M, Merrin J, et al. Nuclear positioning facilitates amoeboid migration along the path of least resistance. Nature. 2019;568:546-550 pubmed publisher
Mehrpouya Bahrami P, Miranda K, Singh N, Zumbrun E, Nagarkatti M, Nagarkatti P. Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity. J Biol Chem. 2019;294:7669-7681 pubmed publisher
Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed publisher
Piao W, Xiong Y, Famulski K, Brinkman C, Li L, Toney N, et al. Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling. Nat Commun. 2018;9:3020 pubmed publisher
Kara E, Bastow C, McKenzie D, Gregor C, Fenix K, Babb R, et al. Atypical chemokine receptor 4 shapes activated B cell fate. J Exp Med. 2018;215:801-813 pubmed publisher
Burbage M, Keppler S, Montaner B, Mattila P, Batista F. The Small Rho GTPase TC10 Modulates B Cell Immune Responses. J Immunol. 2017;199:1682-1695 pubmed publisher
Dong Z, Chen Y, Peng Y, Wang F, Yang Z, Huang G, et al. Concurrent CCR7 Overexpression and RelB Knockdown in Immature Dendritic Cells Induces Immune Tolerance and Improves Skin-Graft Survival in a Murine Model. Cell Physiol Biochem. 2017;42:455-468 pubmed publisher
Xin H, Zhu J, Miao H, Gong Z, Jiang X, Feng X, et al. Adenovirus-Mediated CCR7 and BTLA Overexpression Enhances Immune Tolerance and Migration in Immature Dendritic Cells. Biomed Res Int. 2017;2017:3519745 pubmed publisher
Hwang I, Park C, Harrison K, Kehrl J. Normal Thymocyte Egress, T Cell Trafficking, and CD4+ T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2. J Immunol. 2017;198:2721-2734 pubmed publisher
Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, et al. A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib. J Cell Biol. 2017;216:199-215 pubmed publisher
Gerlach C, Moseman E, Loughhead S, Alvarez D, Zwijnenburg A, Waanders L, et al. The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis. Immunity. 2016;45:1270-1284 pubmed publisher
Takács E, Boto P, Simo E, Csuth T, Toth B, Raveh Amit H, et al. Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3. J Immunol. 2017;198:239-248 pubmed
Schwarz J, Bierbaum V, Merrin J, Frank T, Hauschild R, Bollenbach T, et al. A microfluidic device for measuring cell migration towards substrate-bound and soluble chemokine gradients. Sci Rep. 2016;6:36440 pubmed publisher
Roufaiel M, Gracey E, Siu A, Zhu S, Lau A, Ibrahim H, et al. CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima. Nat Immunol. 2016;17:1263-1272 pubmed publisher
Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed publisher
Poon G, Dong Y, Marshall K, Arif A, Deeg C, Dosanjh M, et al. Hyaluronan Binding Identifies a Functionally Distinct Alveolar Macrophage-like Population in Bone Marrow-Derived Dendritic Cell Cultures. J Immunol. 2015;195:632-42 pubmed publisher
Hwang I, Park C, Harrison K, Boularan C, Galés C, Kehrl J. An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking. J Immunol. 2015;194:2128-39 pubmed publisher
Lee S, Shin S, Lee M, Lee M, Kang T, Park W, et al. A potential protein adjuvant derived from Mycobacterium tuberculosis Rv0652 enhances dendritic cells-based tumor immunotherapy. PLoS ONE. 2014;9:e104351 pubmed publisher
Jung I, Shin S, Lee M, Kang T, Han H, Lee S, et al. Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X. J Immunol. 2014;193:1233-45 pubmed publisher
Ramkhelawon B, Hennessy E, Ménager M, Ray T, Sheedy F, Hutchison S, et al. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med. 2014;20:377-84 pubmed publisher
Hwang I, Hwang K, Park C, Harrison K, Kehrl J. Rgs13 constrains early B cell responses and limits germinal center sizes. PLoS ONE. 2013;8:e60139 pubmed publisher
Wanschel A, Seibert T, Hewing B, Ramkhelawon B, Ray T, van Gils J, et al. Neuroimmune guidance cue Semaphorin 3E is expressed in atherosclerotic plaques and regulates macrophage retention. Arterioscler Thromb Vasc Biol. 2013;33:886-93 pubmed publisher
Köhler T, Reizis B, Johnson R, Weighardt H, Forster I. Influence of hypoxia-inducible factor 1? on dendritic cell differentiation and migration. Eur J Immunol. 2012;42:1226-36 pubmed publisher
Rehm A, Mensen A, Schradi K, Gerlach K, Wittstock S, Winter S, et al. Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs. Blood. 2011;118:1020-33 pubmed publisher
Jimenez F, Quinones M, Martinez H, Estrada C, Clark K, Garavito E, et al. CCR2 plays a critical role in dendritic cell maturation: possible role of CCL2 and NF-kappa B. J Immunol. 2010;184:5571-81 pubmed publisher
Sinclair L, Finlay D, Feijoo C, Cornish G, Gray A, Ager A, et al. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat Immunol. 2008;9:513-21 pubmed publisher
Worbs T, Mempel T, Bölter J, von Andrian U, Forster R. CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo. J Exp Med. 2007;204:489-95 pubmed
Yamashita N, Tashimo H, Matsuo Y, Ishida H, Yoshiura K, Sato K, et al. Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model. J Allergy Clin Immunol. 2006;117:1040-6 pubmed
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
440-M3/CF
SKU :
440-M3-025/CF
product name :
Recombinant Mouse CCL19/MIP-3 beta Protein, CF
Description :
The Recombinant Mouse CCL19/MIP-3 beta Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CCL19/MIP-3 beta Protein, CF has been validated for the following applications: Bioactivity.
target :
CCL19/MIP-3 beta
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
theoretical molecular weight :
9.4 kDa
gene symbol :
Ccl19
details of functionality :
Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.03-0.1 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR7. The ED50 for this effect is 3-15 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q548P0
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse CCL19/MIP-3 beta Protein
USD :
294 USD
alt names :
beta chemokine exodus-3, Beta-chemokine exodus-3, CC chemokine ligand 19, C-C motif chemokine 19, chemokine (C-C motif) ligand 19, CKb11, EBI1-ligand chemokine, ELC, ELCMIP-3-beta, Epstein-Barr virus-induced molecule 1 ligand chemokine, exodus-3, Macrophage inflammatory protein 3 beta, macrophage inflammatory protein 3-beta, MGC34433, MIP3 beta, MIP-3 beta, MIP-3b, MIP3BCK beta-11, SCYA19EBI1 ligand chemokine, small inducible cytokine subfamily A (Cys-Cys), member 19, Small-inducible cytokine A19
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.