Recombinant Human CD39/ENTPD1 Protein, CF | R&D Systems 4397-EN product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD39/ENTPD1 Protein, CF

catalog :

4397-EN

quantity :

10 ug

price :

349 USD

citations: 3

Reference
Perrot I, Michaud H, Giraudon Paoli M, Augier S, Docquier A, Gros L, et al. Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies. Cell Rep. 2019;27:2411-2425.e9 pubmed publisher
Degen H, Borst O, Ziegler M, Mojica Munoz A, Jamasbi J, Walker B, et al. ADPase CD39 Fused to Glycoprotein VI-Fc Boosts Local Antithrombotic Effects at Vascular Lesions. J Am Heart Assoc. 2017;6: pubmed publisher
Townley Tilson W, Wu Y, Ferguson J, Patterson C. The ubiquitin ligase ASB4 promotes trophoblast differentiation through the degradation of ID2. PLoS ONE. 2014;9:e89451 pubmed publisher

product information

brand :

R&D Systems

master code :

4397-EN

SKU :

4397-EN-010

product name :

Recombinant Human CD39/ENTPD1 Protein, CF

description :

The Recombinant Human CD39/ENTPD1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human CD39/ENTPD1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

CD39/ENTPD1

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in Tris, NaCl, CaCl2 and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining

species :

Human

observed molecular weight :

65-90 kDa, reducing conditions

theoretical molecular weight :

51 kDa

gene symbol :

ENTPD1

details of functionality :

Measured by its ability to hydrolyze the 5’-phosphate groups from the substrate adenosine-5’-triphosphate (ATP). The orthophosphate product is measured by a Malachite Green Phosphate Detection Kit (Catalog # DY996 ). The specific activity is 5,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

4397-EN

accessionNumbers :

P49961

applications :

Enzyme Activity

source :

Chinese Hamster Ovary cell line, CHO-derived human CD39/ENTPD1 protein Thr38-Val478, with a C-terminal 6-His tag

2020 USD :

349

2021 USD :

349 USD

alt names :

ADPase, ATPDase, ATP-diphosphatase, CD39, CD39 antigen, CD39EC 3.6.1.5, DKFZp686D194, DKFZp686I093, EC 3.6.1, Ecto-apyrase, Ecto-ATP diphosphohydrolase 1, Ecto-ATPase 1, Ecto-ATPDase 1, ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, FLJ40921, FLJ40959, Lymphoid cell activation antigen, NTPD1, NTPDase 1, NTPDase-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.