Recombinant Human OSMR beta Protein, CF | R&D Systems 4389-OR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human OSMR beta Protein, CF

catalog :

4389-OR-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Rafii P, Cruz P, Ettich J, Seibel C, Padrini G, Wittich C, et al. Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR. J Biol Chem. 2024;300:107251 pubmed publisher
Chollangi S, Mather T, Rodgers K, Ash J. A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor. J Biol Chem. 2012;287:32848-59 pubmed

product information

master code :

4389-OR

SKU :

4389-OR-050

product name :

Recombinant Human OSMR beta Protein, CF

unit size :

50 ug

description :

The Recombinant Human OSMR beta Protein, CF from R&D Systems is derived from NS0. The Recombinant Human OSMR beta Protein, CF has been validated for the following applications: Binding Activity.

target :

OSMR beta

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

120-140 kDa, reducing conditions

theoretical molecular weight :

81 kDa

gene symbol :

OSMR

details of functionality :

Measured by its ability to bind rhOSM in the presence of rhgp130 in a functional ELISA.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_003990

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human OSM R beta protein Glu28-Ser739

source short :

NS0

USD :

456 USD

alt names :

IL-31 receptor subunit beta, IL-31R subunit beta, IL-31RB, IL-31R-beta, Interleukin-31 receptor subunit beta, MGC150627, MGC75127, oncostatin M receptor, oncostatin-M specific receptor beta subunit, oncostatin-M-specific receptor subunit beta, OSM R beta, OSMR, OSMRB, OSMRBMGC150626, PLCA1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage