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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse ErbB4/Her4 Fc Chimera Protein, CF
catalog :
4387-ER-050
quantity :
50 ug
price :
432 USD
more info or order :
product information
master code :
4387-ER
SKU :
4387-ER-050
product name :
Recombinant Mouse ErbB4/Her4 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse ErbB4/Her4 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse ErbB4/Her4 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
ErbB4/Her4
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>85%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
120-140 kDa, reducing conditions
theoretical molecular weight :
97.5 kDa (monomer)
gene symbol :
Erbb4
details of functionality :
Measured by its ability to inhibit the biological activity of Neuregulin-1┐▀1 on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 3-12 ╡g/mL in the presence of 10 ng/mL of Recombinant Human NRG1┐▀1/HRG1┐▀1 Extracellular Domain (Catalog # 377-HB ).
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q61527
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse ErbB4/Her4 protein Mouse ErbB4 (Gln26 - Val657) Accession #Q61527 IEGRMDP Mouse IgG2A (Glu98 - Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, EC 2.7.10, EC 2.7.10.1, HER4, HER4MGC138404, p180erbB4, Proto-oncogene-like protein c-ErbB-4, receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell surface receptor HER4, v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.