Recombinant Mouse Cardiotrophin-1/CT-1 Protein | R&D Systems 438-CT-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Cardiotrophin-1/CT-1 Protein

catalog :

438-CT-010

quantity :

10 ug (also 50 ug)

price :

341 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Khosravi F, Ahmadvand N, Wartenberg M, Sauer H. Induction of Stem-Cell-Derived Cardiomyogenesis by Fibroblast Growth Factor 10 (FGF10) and Its Interplay with Cardiotrophin-1 (CT-1). Biology (Basel). 2022;11: pubmed publisher
Miyake T, Aziz A, McDermott J. Maintenance of the Undifferentiated State in Myogenic Progenitor Cells by TGFβ Signaling is Smad Independent and Requires MEK Activation. Int J Mol Sci. 2020;21: pubmed publisher
Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, et al. Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons. Proc Natl Acad Sci U S A. 2017;114:E2486-E2493 pubmed publisher
Miyake T, Alli N, McDermott J. Nuclear function of Smad7 promotes myogenesis. Mol Cell Biol. 2010;30:722-35 pubmed publisher
Walker E, McGregor N, Poulton I, Pompolo S, Allan E, Quinn J, et al. Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling. J Bone Miner Res. 2008;23:2025-32 pubmed publisher
Gard A, Gavin E, Solodushko V, Pennica D. Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system. Neuroscience. 2004;127:43-52 pubmed
Lesbordes J, Bordet T, Haase G, Castelnau Ptakhine L, Rouhani S, Gilgenkrantz H, et al. In vivo electrotransfer of the cardiotrophin-1 gene into skeletal muscle slows down progression of motor neuron degeneration in pmn mice. Hum Mol Genet. 2002;11:1615-25 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

438-CT

SKU :

438-CT-010

product name :

Recombinant Mouse Cardiotrophin-1/CT-1 Protein

Description :

The Recombinant Mouse Cardiotrophin-1/CT-1 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse Cardiotrophin-1/CT-1 Protein has been validated for the following applications: Bioactivity.

target :

Cardiotrophin-1/CT-1

category :

Proteins and Enzymes

unit size :

10 ug (also 50 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

theoretical molecular weight :

21 kDa

gene symbol :

Ctf1

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.2-0.6 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q60753.1

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse Cardiotrophin-1/CT-1 Protein

USD :

341 USD

alt names :

cardiophin 1, cardiotrophin 1, cardiotrophin-1, Cardiotrophin1, CT-1CT1, CTF1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage