Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein | R&D Systems 437-MR-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein

catalog :

437-MR-100

quantity :

100 ug

price :

540 USD

citations: 4

Reference
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed publisher
Ono Y, Calhabeu F, Morgan J, Katagiri T, Amthor H, Zammit P. BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells. Cell Death Differ. 2011;18:222-34 pubmed publisher
Niessen K, Zhang G, Ridgway J, Chen H, Yan M. ALK1 signaling regulates early postnatal lymphatic vessel development. Blood. 2010;115:1654-61 pubmed publisher
Lopez Coviella I, Mellott T, Kovacheva V, Berse B, Slack B, Zemelko V, et al. Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain. Brain Res. 2006;1088:49-56 pubmed

product information

master code :

437-MR

SKU :

437-MR-100

product name :

Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein

unit size :

100 ug

description :

The Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein has been validated for the following applications: Bioactivity.

target :

BMPR-IA/ALK-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

55 kDa, reducing conditions

theoretical molecular weight :

41.5 kDa (monomer)

gene symbol :

Bmpr1a

details of functionality :

Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.05-0.2 ╡g/mL in the presence of 30 ng/mL of recombinant human BMP-4.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q60607

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse BMPR-IA/ALK-3 protein Mouse BMPR-IA (Gln24 - Arg152) Accession # Q60607 IEGRMD Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

540 USD

alt names :

ACVRLK310q23del, ALK-3, ALK3EC 2.7.11.30, BMP type-1A receptor, BMPR1A, BMPR-1A, BMPRIA, bone morphogenetic protein receptor type-1A, bone morphogenetic protein receptor, type IA, CD292, CD292 antigen, EC 2.7.11, Serine/threonine-protein kinase receptor R5, SKR5, type II-like kinase 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.