product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein
catalog :
437-MR-100
quantity :
100 ug
price :
529 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed publisher
Ono Y, Calhabeu F, Morgan J, Katagiri T, Amthor H, Zammit P. BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells. Cell Death Differ. 2011;18:222-34 pubmed publisher
Niessen K, Zhang G, Ridgway J, Chen H, Yan M. ALK1 signaling regulates early postnatal lymphatic vessel development. Blood. 2010;115:1654-61 pubmed publisher
Lopez Coviella I, Mellott T, Kovacheva V, Berse B, Slack B, Zemelko V, et al. Developmental pattern of expression of BMP receptors and Smads and activation of Smad1 and Smad5 by BMP9 in mouse basal forebrain. Brain Res. 2006;1088:49-56 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
437-MR
SKU :
437-MR-100
product name :
Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein
Description :
The Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein has been validated for the following applications: Bioactivity.
target :
BMPR-IA/ALK-3
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
55 kDa, reducing conditions
theoretical molecular weight :
41.5 kDa (monomer)
gene symbol :
Bmpr1a
details of functionality :
Measured by its ability to inhibit rhBMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.05-0.2 µg/mL in the presence of 30 ng/mL of recombinant human BMP-4.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q60607
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse BMPR-IA/ALK-3 Fc Chimera Protein
USD :
529 USD
alt names :
ACVRLK310q23del, ALK-3, ALK3EC 2.7.11.30, BMP type-1A receptor, BMPR1A, BMPR-1A, BMPRIA, bone morphogenetic protein receptor type-1A, bone morphogenetic protein receptor, type IA, CD292, CD292 antigen, EC 2.7.11, Serine/threonine-protein kinase receptor R5, SKR5, type II-like kinase 3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.