product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat Neuroligin 1/NLGN1 Protein, CF
catalog :
4340-NL-050
quantity :
50 ug
price :
458 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Wierda K, Toft Bertelsen T, Gøtzsche C, Pedersen E, Korshunova I, Nielsen J, et al. The soluble neurexin-1β ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission. Sci Rep. 2020;10:18041 pubmed publisher
Brito Moreira J, Lourenco M, Oliveira M, Ribeiro F, Ledo J, Diniz L, et al. Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice. J Biol Chem. 2017;292:7327-7337 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
4340-NL
SKU :
4340-NL-050
product name :
Recombinant Rat Neuroligin 1/NLGN1 Protein, CF
Description :
The Recombinant Rat Neuroligin 1/NLGN1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat Neuroligin 1/NLGN1 Protein, CF has been validated for the following applications: Bioactivity.
target :
Neuroligin 1/NLGN1
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
observed molecular weight :
85-105 kDa, reducing conditions
theoretical molecular weight :
71 kDa
gene symbol :
Nlgn1
details of functionality :
Measured by its binding ability in a functional ELISA. When recombinant rat Neuroligin 1 is immobilized at 5 µg/mL, biotinylated recombinant human Neurexin 1 beta Fc Chimera binds with an apparent KD 20 nM.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q62765 (isoform 4)
applications :
Bioactivity
source :
NS0-derived Recombinant Rat Neuroligin 1/NLGN1 Protein
USD :
458 USD
alt names :
EC 3.1.1, EC 3.1.1.1, KIAA1070neuroligin-1, MGC45115, neuroligin 1, NL1, Nlg, NLGN1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.