product summary
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company name :
R&D Systems
product type :
antibody
product name :
PARP Antibody
catalog :
4338-MC-50
quantity :
50 ug
price :
219 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C2-10
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig s4e
Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 9
  • western blot; human; 1:1000; loading ...; fig 4a
Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed publisher
Han A, Li C, Zahed T, Wong M, Smith I, Hoedel K, et al. Calreticulin is a Critical Cell Survival Factor in Malignant Neoplasms. PLoS Biol. 2019;17:e3000402 pubmed publisher
Ciardullo C, Aptullahoglu E, Woodhouse L, Lin W, Wallis J, Marr H, et al. Non-genotoxic MDM2 inhibition selectively induces pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells. Haematologica. 2019;: pubmed publisher
Sheets S, Potempa J, Travis J, Fletcher H, Casiano C. Gingipains from Porphyromonas gingivalis W83 synergistically disrupt endothelial cell adhesion and can induce caspase-independent apoptosis. Infect Immun. 2006;74:5667-78 pubmed
Armstrong T, Packham G, Murphy L, Bateman A, Conti J, Fine D, et al. Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma. Clin Cancer Res. 2004;10:7427-37 pubmed
product information
brand :
R&D Systems
SKU :
4338-MC-50
product name :
PARP Antibody
unit sizes :
50 ug
description :
The PARP Antibody from R&D Systems is a mouse monoclonal antibody to PARP. This antibody reacts with multi-species. The PARP Antibody has been validated for the following applications: Western Blot, Immunocytochemistry.
target :
PARP
category :
Primary Antibodies
buffer :
PBS with 0.2% BSA and 0.05% sodium azide
clonality :
Monoclonal
clone :
C2-10
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length calf thymus poly(ADP-ribose) polymerase (PARP)
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Multi-Species
specificity :
This antibody recognizes both the full length (116 kDa) and 85 kDa cleavage fragment of PARP in human, monkey, mouse, rat, bovine and hamster systems. Chicken PARP is not recognized. Other species have not been tested.
gene symbol :
PARP1
catalog number base :
4338-MC
applications :
Western Blot, Immunocytochemistry
USD :
219 USD
applications abr :
WB, ICC
alt names :
ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADPRT, ADPRT 1, ADPRTADP-ribosyltransferase NAD(+), EC 2.4.2, EC 2.4.2.30, NAD(+) ADP-ribosyltransferase 1, PARP apoptosis, PARP1, PARP-1, PARPADPRT1, poly (ADP-ribose) polymerase 1, poly (ADP-ribose) polymerase family, member 1, poly [ADP-ribose] polymerase 1, poly(ADP-ribose) polymerase, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, Poly[ADP-ribose] synthase 1, PPOL, PPOLpADPRT-1
storage :
This product is stable as shipped for a least one year when stored at Avoid multiple freeze/thaw cycles by storage in appropriate aliquots. Do not store in a frost-free freezer.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.