product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat IGF-I/IGF-1 Protein, CF
catalog :
4326-RG-050
quantity :
50 ug
price :
235 USD
more info or order :
R&D Systems product webpage
citations: 10
Reference
Karayay B, Olze H, Szczepek A. Degranulation of Murine Resident Cochlear Mast Cells: A Possible Factor Contributing to Cisplatin-Induced Ototoxicity and Neurotoxicity. Int J Mol Sci. 2023;24: pubmed publisher
Szczepek A, Dudnik T, Karayay B, Sergeeva V, Olze H, Smorodchenko A. Mast Cells in the Auditory Periphery of Rodents. Brain Sci. 2020;10: pubmed publisher
Ding X, Yang W, Ren Q, Hu J, Yang S, Han W, et al. Serum IgG-induced microglial activation enhances neuronal cytolysis via the NO/sGC/PKG pathway in children with opsoclonus-myoclonus syndrome and neuroblastoma. J Neuroinflammation. 2020;17:190 pubmed publisher
Chen H, Zhu H, Yang J, Zhu Y, Mei J, Shen H, et al. Role of Programmed Cell Death 4 (PDCD4)-Mediated Akt Signaling Pathway in Vascular Endothelial Cell Injury Caused by Lower-Extremity Ischemia-Reperfusion in Rats. Med Sci Monit. 2019;25:4811-4818 pubmed publisher
Yuan J, Zhang Q, Gong C, Wang F, Huang J, Yang G, et al. Young plasma ameliorates aging-related acute brain injury after intracerebral hemorrhage. Biosci Rep. 2019;39: pubmed publisher
Zhu H, Xue C, Yao M, Wang H, Zhang P, Qian T, et al. miR-129 controls axonal regeneration via regulating insulin-like growth factor-1 in peripheral nerve injury. Cell Death Dis. 2018;9:720 pubmed publisher
Fornaro M, Hinken A, Needle S, Hu E, Trendelenburg A, Mayer A, et al. Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells. Am J Physiol Endocrinol Metab. 2014;306:E150-6 pubmed publisher
Grinberg Y, van Drongelen W, Kraig R. Insulin-like growth factor-1 lowers spreading depression susceptibility and reduces oxidative stress. J Neurochem. 2012;122:221-9 pubmed publisher
Asumda F, Chase P. Age-related changes in rat bone-marrow mesenchymal stem cell plasticity. BMC Cell Biol. 2011;12:44 pubmed publisher
Gilbert R, Huang Q, Thai K, Advani S, Lee K, Yuen D, et al. Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptor. Kidney Int. 2011;79:1312-21 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
4326-RG
SKU :
4326-RG-050
product name :
Recombinant Rat IGF-I/IGF-1 Protein, CF
Description :
The Recombinant Rat IGF-I/IGF-1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Rat IGF-I/IGF-1 Protein, CF has been validated for the following applications: Bioactivity.
target :
IGF-I/IGF-1
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Rat
theoretical molecular weight :
8.8 kDa
gene symbol :
Igf1
details of functionality :
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.6-3 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAA41386
applications :
Bioactivity
source :
E. coli-derived Recombinant Rat IGF-I/IGF-1 Protein
USD :
235 USD
alt names :
IBP1, IGF1, IGF-1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, Somatomedin A, Somatomedin C, Somatomedin-C
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.