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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Prolyl Oligopeptidase/PREP Protein, CF
catalog :
4308-SE-010
quantity :
10 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 5
Reference
Ivanov I, Vasileva A, Tasheva D, Dimitrova M. Isolation and characterization of natural inhibitors of post-proline specific peptidases from the leaves of Cotinus coggygria Scop. J Ethnopharmacol. 2023;314:116508 pubmed publisher
Cho J, Yang E, Quan W, Nam E, Cheon H. Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects. Sci Rep. 2020;10:21280 pubmed publisher
Becker B, Nazir F, Brinkmalm G, Camporesi E, Kvartsberg H, Portelius E, et al. Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase. Mol Neurodegener. 2018;13:47 pubmed publisher
Chen M, Lei X, Shi C, Huang M, Li X, Wu B, et al. Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents. J Clin Invest. 2017;127:3689-3701 pubmed publisher
Dunshee D, Bainbridge T, Kljavin N, Zavala Solorio J, Schroeder A, Chan R, et al. Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21. J Biol Chem. 2016;291:5986-96 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
4308-SE
SKU :
4308-SE-010
product name :
Recombinant Human Prolyl Oligopeptidase/PREP Protein, CF
Description :
The Recombinant Human Prolyl Oligopeptidase/PREP Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Prolyl Oligopeptidase/PREP Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Prolyl Oligopeptidase/PREP
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in MES, NaCl and Glycerol.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
73 kDa, reducing conditions
theoretical molecular weight :
81 kDa
gene symbol :
PREP
details of functionality :
Measured by its ability to convert the substrate benzyloxycarbonyl-Gly-Pro-7-amido-4-methylcoumarin (Z-GP-AMC) to Z-Gly-Pro and 7-amino-4-methylcoumarin (AMC). The specific activity is 3,500 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P48147
applications :
Enzyme Activity
source :
Sf 21 (baculovirus)-derived Recombinant Human Prolyl Oligopeptidase/PREP Protein
USD :
423 USD
alt names :
dJ355L5.1 (prolyl endopeptidase), EC 3.4.21.26, MGC16060, PE, PEP, Post-proline cleaving enzyme, PREP, prolyl endopeptidase, prolyl oligopeptidase, rPop
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.