Recombinant Human MSP/MST1 (Cys672Ala) Protein, CF | R&D Systems 4306-MS-010/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MSP/MST1 (Cys672Ala) Protein, CF

catalog :

4306-MS-010/CF

quantity :

10 ug

price :

373 USD

citations: 4

Reference
Hunt B, Jones A, Lester C, Davis J, Benight N, Waltz S. RON (MST1R) and HGFL (MST1) Co-Overexpression Supports Breast Tumorigenesis through Autocrine and Paracrine Cellular Crosstalk. Cancers (Basel). 2022;14: pubmed publisher
Dey A, Allen J, Fraser J, Snyder L, Tian Y, Zhang L, et al. Neuroprotective Role of the Ron Receptor Tyrosine Kinase Underlying Central Nervous System Inflammation in Health and Disease. Front Immunol. 2018;9:513 pubmed publisher
Privette Vinnedge L, Benight N, Wagh P, Pease N, Nashu M, Serrano López J, et al. The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers. Oncogene. 2015;34:2325-36 pubmed publisher
Wang X, Yennawar N, Hankey P. Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain. Cell Commun Signal. 2014;12:28 pubmed publisher

product information

master code :

4306-MS/CF

SKU :

4306-MS-010/CF

product name :

Recombinant Human MSP/MST1 (Cys672Ala) Protein, CF

unit size :

10 ug

description :

The Recombinant Human MSP/MST1 (Cys672Ala) Protein, CF from R&D Systems is derived from CHO.

target :

MSP/MST1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

60 kDa and 30 kDa, reducing conditions

theoretical molecular weight :

53 kDa ( alpha -chain), 25 kDa (▀-chain)

gene symbol :

MST1

details of functionality :

Measured by its binding ability in a functional ELISA. Recombinant Human MSP/MST1 (Cys672Ala) (Catalog # 4306-MS/CF) binds to Recombinant Human MSPR/Ron Protein (Catalog # 1947-MS ) with an ED50 of 4.00-32.0 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAA59872

source long :

Chinese Hamster Ovary cell line, CHO-derived human MSP/MST1 protein Gln19-Arg483 (alpha) & Val484-Gly711 (Cys672Ala) (beta)

source short :

CHO

USD :

373 USD

alt names :

D3F15S2, EC 3.4.21, hepatocyte growth factor-like protein homolog, HGFL, HGFLhepatocyte growth factor-like protein, macrophage stimulating 1 (hepatocyte growth factor-like), Macrophage stimulatory protein, Macrophage-stimulating protein, MSPDNF15S2, MST1, NF15S2, SF2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.