Recombinant Mouse GFR alpha-2 Fc Chimera Protein, CF | R&D Systems 429-FR-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse GFR alpha-2 Fc Chimera Protein, CF

catalog :

429-FR-100

quantity :

100 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher
Liu Y, Giannopoulou E, Wen D, Falciatori I, Elemento O, Allis C, et al. Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells. Nat Commun. 2016;7:11275 pubmed publisher
Fonseca Pereira D, Arroz Madeira S, Rodrigues Campos M, Barbosa I, Domingues R, Bento T, et al. The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function. Nature. 2014;514:98-101 pubmed publisher

product information

master code :

429-FR

SKU :

429-FR-100

product name :

Recombinant Mouse GFR alpha-2 Fc Chimera Protein, CF

unit size :

100 ug

description :

The Recombinant Mouse GFR alpha-2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse GFR alpha-2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

GFR alpha-2/GDNF R alpha-2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

90 kDa, reducing conditions

theoretical molecular weight :

74 kDa (monomer)

gene symbol :

Gfra2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse Neurturin (Catalog # 477-MN ) at 1 ╡g/mL binds Recombinant Mouse GFR alpha -2/GDNF R alpha -2 Fc Chimera with an apparent KD 5 nM.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q3UUD8

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse GFR alpha-2/GDNF R alpha-2 protein Mouse GFRa-2 (Ser22-Ser441) Accession # Q3UUD8 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

GDNF family receptor alpha 2, GDNF family receptor alpha-2, GDNF R alpha-2, GDNF receptor alpha-2, GDNF receptor beta, GDNFR-alpha-2, GDNFR-beta, GDNFRBRET ligand 2, GFR alpha2, GFRa-2, GFRA2, GFR-alpha 2, GFR-alpha-2, glial cell line derived neurotrophic factor receptor, beta, Neurturin receptor alpha, NRTNR-alpha, NTNRA, NTNR-alpha, PI-linked cell-surface accessory protein, RETL2TGF-beta-related neurotrophic factor receptor 2, TGF-beta related neurotrophic factor receptor 2, TRN receptor, GPI-anchored, TRNR2NRTNR-ALPHA

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage