product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CCL12/MCP-5 Protein, CF
catalog :
428-P5-025/CF
quantity :
25 ug
price :
300 USD
more info or order :
citations: 3
Reference
Popiolek Barczyk K, Ciechanowska A, Ciapała K, Pawlik K, Oggioni M, Mercurio D, et al. The CCL2/CCL7/CCL12/CCR2 pathway is substantially and persistently upregulated in mice after traumatic brain injury, and CCL2 modulates the complement system in microglia. Mol Cell Probes. 2020;54:101671 pubmed publisher
Kwiatkowski K, Popiolek Barczyk K, Piotrowska A, Rojewska E, Ciapała K, Makuch W, et al. Chemokines CCL2 and CCL7, but not CCL12, play a significant role in the development of pain-related behavior and opioid-induced analgesia. Cytokine. 2019;119:202-213 pubmed publisher
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, et al. The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood. 2005;105:31-9 pubmed
product information
master code :
428-P5/CF
SKU :
428-P5-025/CF
product name :
Recombinant Mouse CCL12/MCP-5 Protein, CF
unit size :
25 ug
description :
The Recombinant Mouse CCL12/MCP-5 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CCL12/MCP-5 Protein, CF has been validated for the following applications: Bioactivity.
target :
CCL12/MCP-5
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
theoretical molecular weight :
9.3 kDa
gene symbol :
Ccl12
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR2A. The ED50 for this effect is 5-30 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q62401.1
applications :
Bioactivity
source long :
E. coli -derived mouse CCL12/MCP-5 protein Gly23-Gly104
source short :
E. coli
USD :
300 USD
alt names :
C-C motif chemokine 12, chemokine (C-C motif) ligand 12, MCP5, MCP-5, Scya12
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.