Recombinant Mouse CXCL17/VCC-1 Protein | R&D Systems 4270-DM-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CXCL17/VCC-1 Protein

catalog :

4270-DM-025

quantity :

25 ug

price :

300 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Shimada S, Makino K, Jinnin M, Sawamura S, Kawano Y, Ide M, et al. CXCL17-mediated downregulation of type I collagen via MMP1 and miR-29 in skin fibroblasts possibly contributes to the fibrosis in systemic sclerosis. J Dermatol Sci. 2020;100:183-191 pubmed publisher
Hsu Y, Yen M, Chang W, Tsai P, Pan Y, Liao S, et al. CXCL17-derived CD11b+Gr-1+ myeloid-derived suppressor cells contribute to lung metastasis of breast cancer through platelet-derived growth factor-BB. Breast Cancer Res. 2019;21:23 pubmed publisher
Burkhardt A, Maravillas Montero J, Carnevale C, Vilches Cisneros N, Flores J, Hevezi P, et al. CXCL17 is a major chemotactic factor for lung macrophages. J Immunol. 2014;193:1468-74 pubmed publisher

product information

master code :

4270-DM

SKU :

4270-DM-025

product name :

Recombinant Mouse CXCL17/VCC-1 Protein

unit size :

25 ug

description :

The Recombinant Mouse CXCL17/VCC-1 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CXCL17/VCC-1 Protein has been validated for the following applications: Bioactivity.

target :

CXCL17/VCC-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

theoretical molecular weight :

10.3 kDa

gene symbol :

Cxcl17

details of functionality :

Measured by its ability to induce VEGF expression in mouse endothelial cells. Weinstein, E.J. et al . (2006) BBRC 350 :74. The ED50 for this effect is 1-5 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q5UW37.1

applications :

Bioactivity

source long :

E. coli -derived mouse CXCL17/VCC-1 protein Ser23-Leu119

source short :

E. coli

USD :

300 USD

alt names :

Chemokine (C-X-C Motif) Ligand 17, C-X-C Motif Chemokine 17, CXCL17, Dcip1, Dendritic Cell And Monocyte Chemokine-Like Protein, DMC, UNQ473, VCC1, VCC-1, VEGF Coregulated Chemokine 1, VEGF Co-Regulated Chemokine 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage