product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Flt-3 Ligand/FLT3L Protein
catalog :
427-FL-005
quantity :
5 ug (also 25 ug)
price :
181 USD
more info or order :
citations: 90
Reference
Nicolao M, Rodrígues C, Coccimiglio M, Ledo C, Docena G, Cumino A. Characterization of protein cargo of Echinococcus granulosus extracellular vesicles in drug response and its influence on immune response. Parasit Vectors. 2023;16:255 pubmed publisher
Palam L, Ramdas B, Pickerell K, Pasupuleti S, Kanumuri R, Cesarano A, et al. Loss of Dnmt3a impairs hematopoietic homeostasis and myeloid cell skewing via the PI3Kinase pathway. JCI Insight. 2023;8: pubmed publisher
Cui X, Zhang C, Wang F, Zhao X, Wang S, Liu J, et al. Latexin regulates sex dimorphism in hematopoiesis via gender-specific differential expression of microRNA 98-3p and thrombospondin 1. Cell Rep. 2023;42:112274 pubmed publisher
Liu J, Cheng Y, Zhang X, Chen Y, Zhu H, Chen K, et al. Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity. Cell Rep. 2023;42:111991 pubmed publisher
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, et al. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia. EMBO Mol Med. 2022;:e15631 pubmed publisher
Uslu M, Albayrak E, Kocaba x15f F. Competitive inhibition of IL-2/IL-2R has a dual effect on HSC ex vivo expansion and IL-2R (CD25) content. Int Immunopharmacol. 2022;110:109035 pubmed publisher
Hayashi Y, Kawabata K, Tanaka Y, Uehara Y, Mabuchi Y, Murakami K, et al. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis. Cell Rep. 2022;39:110805 pubmed publisher
Jeong J, Jung I, Kim J, Jeon S, Hyeon D, Min H, et al. BAP1 shapes the bone marrow niche for lymphopoiesis by fine-tuning epigenetic profiles in endosteal mesenchymal stromal cells. Cell Death Differ. 2022;: pubmed publisher
Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, et al. A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Cell Rep. 2021;36:109576 pubmed publisher
Ohashi N, Terashima T, Katagi M, Nakae Y, Okano J, Suzuki Y, et al. GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS. Sci Rep. 2021;11:12803 pubmed publisher
Herbst F, Lang T, Eckert E, Wünsche P, Wurm A, Kindinger T, et al. The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision. Leukemia. 2021;35:2948-2963 pubmed publisher
Lu J, Li S, Li X, Zhao W, Duan X, Gu X, et al. Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging. Aging Cell. 2021;20:e13353 pubmed publisher
Tereshchenko V, Bulygin A, Zavodskii R, Maksyutov A, Kurilin V, Fisher M, et al. The murine DCs transfected with DNA-plasmid encoding CCR9 demonstrate the increased migration to CCL25 and thymic cells in vitro and to the thymus in vivo. Cytokine. 2021;142:155473 pubmed publisher
Fahl S, Contreras A, Verma A, Qiu X, Harly C, Radtke F, et al. The E protein-TCF1 axis controls γδ T cell development and effector fate. Cell Rep. 2021;34:108716 pubmed publisher
Gurczynski S, Pereira N, Hrycaj S, Wilke C, Zemans R, Moore B. Stem cell transplantation uncovers TDO-AHR regulation of lung dendritic cells in herpesvirus-induced pathology. JCI Insight. 2021;6: pubmed publisher
Papaioannou N, Salei N, Rambichler S, Ravi K, Popovic J, Küntzel V, et al. Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice. Nat Commun. 2021;12:464 pubmed publisher
Hong Y, Singh N, Bamopoulos S, Gjerga E, Schmalbrock L, Balabanian K, et al. Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System. Biomedicines. 2020;8: pubmed publisher
Girotra M, Trachsel V, Roch A, Lutolf M. In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro. Int J Mol Sci. 2020;21: pubmed publisher
Wada M, Shimada Y, Iizuka S, Ishii N, Hiraki H, Tachibana T, et al. Ex Vivo Gene Therapy Treats Bone Complications of Mucopolysaccharidosis Type II Mouse Models through Bone Remodeling Reactivation. Mol Ther Methods Clin Dev. 2020;19:261-274 pubmed publisher
Bogert N, Furkel J, Din S, Braren I, Eckstein V, Muller J, et al. A novel approach to genetic engineering of T-cell subsets by hematopoietic stem cell infection with a bicistronic lentivirus. Sci Rep. 2020;10:13740 pubmed publisher
Garcia Perez L, van Eggermond M, Van Roon L, Vloemans S, Cordes M, Schambach A, et al. Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID. Mol Ther Methods Clin Dev. 2020;17:666-682 pubmed publisher
Zhao Y, Wang J, Min Z, Peng L, Qi S, Lin W. I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis. Mediators Inflamm. 2020;2020:6947482 pubmed publisher
Bertho J, Kereselidze D, Manens L, Culeux C, Magneron V, Surette J, et al. Hto, Tritiated Amino Acid Exposure and External Exposure Induce Differential Effects on Hematopoiesis and Iron Metabolism. Sci Rep. 2019;9:19919 pubmed publisher
Chen E, Thompson P, Zuniga Pflucker J. RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors. Nat Immunol. 2019;20:1456-1468 pubmed publisher
Gong Z, Shang B, Chu Y, Chen X, Li Q, Liu K, et al. Fibrotic liver microenvironment promotes Dll4 and SDF-1-dependent T-cell lineage development. Cell Death Dis. 2019;10:440 pubmed publisher
Huang P, Li X, Meng Y, Yuan B, Liu T, Jiao M, et al. Interleukin-33 regulates hematopoietic stem cell regeneration after radiation injury. Stem Cell Res Ther. 2019;10:123 pubmed publisher
Vannini N, Campos V, Girotra M, Trachsel V, Rojas Sutterlin S, Tratwal J, et al. The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance. Cell Stem Cell. 2019;24:405-418.e7 pubmed publisher
Goossens S, Wang J, Tremblay C, De Medts J, T Sas S, Nguyen T, et al. ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms. Haematologica. 2019;: pubmed publisher
Ribezzo F, Snoeren I, Ziegler S, Stoelben J, Olofsen P, Henic A, et al. Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome. Leukemia. 2019;: pubmed publisher
Boscolo Sesillo F, Fox D, Sacco A. Muscle Stem Cells Give Rise to Rhabdomyosarcomas in a Severe Mouse Model of Duchenne Muscular Dystrophy. Cell Rep. 2019;26:689-701.e6 pubmed publisher
Hillyer L, Woodward B. Acutely malnourished weanling mice administered Flt3 ligand can support a cell-mediated inflammatory response. Cytokine. 2019;113:39-49 pubmed publisher
Inoue M, Okamoto K, Terashima A, Nitta T, Muro R, Negishi Koga T, et al. Arginine methylation controls the strength of γc-family cytokine signaling in T cell maintenance. Nat Immunol. 2018;19:1265-1276 pubmed publisher
Martin S, Fitter S, El Khawanky N, Grose R, Walkley C, Purton L, et al. mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis. Sci Rep. 2018;8:14501 pubmed publisher
Gonzalez Quintial R, Nguyen A, Kono D, Oldstone M, Theofilopoulos A, Baccala R. Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition. PLoS ONE. 2018;13:e0203118 pubmed publisher
Lin Y, Wang L, Lee C, Chen S. Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses. Sci Rep. 2018;8:12184 pubmed publisher
Kim S, Lee S, Park H, Lee S, Im W, Kim Y, et al. Anti-cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells. BMC Complement Altern Med. 2018;18:218 pubmed publisher
Wünsche P, Eckert E, Holland Letz T, Paruzynski A, Hotz Wagenblatt A, Fronza R, et al. Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs. Cell Stem Cell. 2018;23:132-146.e9 pubmed publisher
Tasian S, Casas J, Posocco D, Gandre Babbe S, Gagne A, Liang G, et al. Mutation-specific signaling profiles and kinase inhibitor sensitivities of juvenile myelomonocytic leukemia revealed by induced pluripotent stem cells. Leukemia. 2019;33:181-190 pubmed publisher
Sasine J, Himburg H, Termini C, Roos M, Tran E, Zhao L, et al. Wild-type Kras expands and exhausts hematopoietic stem cells. JCI Insight. 2018;3: pubmed publisher
Nam G, Lee E, Kim Y, Hong Y, Choi Y, Ryu M, et al. Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer. Nat Commun. 2018;9:2165 pubmed publisher
Cheung L, Tickner J, Hughes A, Skut P, Howlett M, Foley B, et al. New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment. Leukemia. 2018;32:2326-2338 pubmed publisher
Fang H, El Farran C, Xing Q, Zhang L, Li H, Lim B, et al. Global H3.3 dynamic deposition defines its bimodal role in cell fate transition. Nat Commun. 2018;9:1537 pubmed publisher
Kanayama M, Kato Y, Tsuji T, Konoeda Y, Hashimoto A, Kanauchi O, et al. Enhancement of immunomodulative effect of lactic acid bacteria on plasmacytoid dendritic cells with sucrose palmitate. Sci Rep. 2018;8:3147 pubmed publisher
Xiao Y, Palomero J, Grabowska J, Wang L, de Rink I, van Helvert L, et al. Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor. Blood Adv. 2017;1:1993-2006 pubmed publisher
Huang J, Khan A, Au B, Barber D, Lopez Vasquez L, Prokopishyn N, et al. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017;5:241-258 pubmed publisher
Smith M, Reichenbach D, Parker S, Riddle M, Mitchell J, Osum K, et al. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. JCI Insight. 2017;2: pubmed publisher
Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed publisher
Shukla S, Langley M, Singh J, Edgar J, Mohtashami M, Zuniga Pflucker J, et al. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1. Nat Methods. 2017;14:531-538 pubmed publisher
Kumar S, Sunagar R, Pham G, Franz B, Rosa S, Hazlett K, et al. Differential Cultivation of Francisella tularensis Induces Changes in the Immune Response to and Protective Efficacy of Whole Cell-Based Inactivated Vaccines. Front Immunol. 2016;7:677 pubmed publisher
Himburg H, Doan P, Quarmyne M, Yan X, Sasine J, Zhao L, et al. Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms. Nat Med. 2017;23:91-99 pubmed publisher
Famili F, Perez L, Naber B, Noordermeer J, Fradkin L, Staal F. The non-canonical Wnt receptor Ryk regulates hematopoietic stem cell repopulation in part by controlling proliferation and apoptosis. Cell Death Dis. 2016;7:e2479 pubmed publisher
Cheng H, Ang H, A El Farran C, Li P, Fang H, Liu T, et al. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors. Nat Commun. 2016;7:13396 pubmed publisher
Zhao L, Frock R, Du Z, Hu J, Chen L, Krangel M, et al. Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development. J Exp Med. 2016;213:1921-36 pubmed publisher
Pfaender S, Grabski E, Detje C, Riebesehl N, Lienenklaus S, Steinmann E, et al. Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner. PLoS Pathog. 2016;12:e1005736 pubmed publisher
Elshikha A, Lu Y, Chen M, Akbar M, Zeumer L, Ritter A, et al. Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus. PLoS ONE. 2016;11:e0156583 pubmed publisher
Tengvall S, Eneljung T, Jirholt P, Turesson O, Wing K, Holmdahl R, et al. Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis. PLoS ONE. 2016;11:e0154630 pubmed publisher
Lee S, Dvinge H, Kim E, Cho H, Micol J, Chung Y, et al. Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins. Nat Med. 2016;22:672-8 pubmed publisher
Niedzielska M, Raffi F, Tel J, Muench S, Jozefowski K, Alati N, et al. Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production. J Immunol. 2015;195:1753-62 pubmed publisher
Lee S, Park H, Jeon S, Lee C, Seong R, Park S, et al. Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages. PLoS ONE. 2015;10:e0132329 pubmed publisher
Flores M, Chew C, Tyan K, Huang W, SALEM A, Clynes R. FcγRIIB prevents inflammatory type I IFN production from plasmacytoid dendritic cells during a viral memory response. J Immunol. 2015;194:4240-50 pubmed publisher
Römmler F, Hammel M, Waldhuber A, Müller T, Jurk M, Uhlmann E, et al. Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells. PLoS ONE. 2015;10:e0116703 pubmed publisher
Scheuplein V, Seifried J, Malczyk A, Miller L, Höcker L, Vergara Alert J, et al. High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus. J Virol. 2015;89:3859-69 pubmed publisher
Tsuji R, Koizumi H, Aoki D, Watanabe Y, Sugihara Y, Matsushita Y, et al. Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4). J Biol Chem. 2015;290:4410-21 pubmed publisher
Martínez López M, Iborra S, Conde Garrosa R, Sancho D. Batf3-dependent CD103+ dendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice. Eur J Immunol. 2015;45:119-29 pubmed publisher
Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, et al. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood. 2014;124:1393-403 pubmed publisher
Patnode M, Bando J, Krummel M, Locksley R, Rosen S. Leukotriene B4 amplifies eosinophil accumulation in response to nematodes. J Exp Med. 2014;211:1281-8 pubmed publisher
Dai P, Wang W, Cao H, Avogadri F, Dai L, Drexler I, et al. Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway. PLoS Pathog. 2014;10:e1003989 pubmed publisher
Treanor L, Zhou S, Janke L, Churchman M, Ma Z, Lu T, et al. Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential. J Exp Med. 2014;211:701-13 pubmed publisher
Wallington Beddoe C, Powell J, Tong D, Pitson S, Bradstock K, Bendall L. Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression. Cancer Res. 2014;74:2803-15 pubmed publisher
Krutikov K, Zheng Y, Chesney A, Huang X, Vaags A, Evdokimova V, et al. Ectopic TLX1 expression accelerates malignancies in mice deficient in DNA-PK. PLoS ONE. 2014;9:e89649 pubmed publisher
Coffey F, Lee S, Buus T, Lauritsen J, Wong G, Joachims M, et al. The TCR ligand-inducible expression of CD73 marks ?? lineage commitment and a metastable intermediate in effector specification. J Exp Med. 2014;211:329-43 pubmed publisher
Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, et al. Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports. 2013;1:545-59 pubmed publisher
Narendra S, Chalise J, Höök N, Magnusson M. Dendritic cells activated by double-stranded RNA induce arthritis via autocrine type I IFN signaling. J Leukoc Biol. 2014;95:661-6 pubmed publisher
Gao X, Johnson K, Chang Y, Boyer M, Dewey C, Zhang J, et al. Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo. J Exp Med. 2013;210:2833-42 pubmed publisher
Pereira C, Chang B, Qiu J, Niu X, Papatsenko D, Hendry C, et al. Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell. 2013;13:205-18 pubmed publisher
Manley N, Caso J, Works M, Cutler A, Zemlyak I, Sun G, et al. Derivation of injury-responsive dendritic cells for acute brain targeting and therapeutic protein delivery in the stroke-injured rat. PLoS ONE. 2013;8:e61789 pubmed publisher
Kim D, Niewiesk S. Synergistic induction of interferon ? through TLR-3 and TLR-9 agonists identifies CD21 as interferon ? receptor for the B cell response. PLoS Pathog. 2013;9:e1003233 pubmed publisher
Gatto D, Wood K, Caminschi I, Murphy Durland D, Schofield P, Christ D, et al. The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells. Nat Immunol. 2013;14:446-53 pubmed publisher
Smith C, Berry D, McGlade C. The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor. J Cell Sci. 2013;126:1366-80 pubmed publisher
Iborra S, Izquierdo H, Martínez López M, Blanco Menéndez N, Reis E Sousa C, Sancho D. The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice. J Clin Invest. 2012;122:1628-43 pubmed publisher
Shinohara M, Kim J, Garcia V, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008;29:68-78 pubmed publisher
Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, et al. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur J Immunol. 2007;37:2695-706 pubmed
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
Kared H, Adle Biassette H, Fois E, Masson A, Bach J, Chatenoud L, et al. Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling. Immunity. 2006;25:823-34 pubmed
Braun B, Archard J, Van Ziffle J, Tuveson D, Jacks T, Shannon K. Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo. Blood. 2006;108:2041-4 pubmed
Azhipa O, Kimizuka K, Nakao A, Toyokawa H, Okuda T, Neto J, et al. Comparative analysis of the fate of donor dendritic cells and B cells and their influence on alloreactive T cell responses under tacrolimus immunosuppression. Clin Immunol. 2005;114:199-209 pubmed
Miller M, Hejazi A, Wei S, Cahalan M, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A. 2004;101:998-1003 pubmed
Asselin Paturel C, Brizard G, Pin J, Briere F, Trinchieri G. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J Immunol. 2003;171:6466-77 pubmed
Blumenthal R, Reising A, Leon E, Goldenberg D. Modulation of marrow proliferation and chemosensitivity by tumor-produced cytokines from syngeneic pancreatic tumor lines. Clin Cancer Res. 2002;8:1301-9 pubmed
Shih C, Hu M, Hu J, Weng Y, Yazaki P, Medeiros J, et al. A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood. 2000;95:1957-66 pubmed
image
image 1 :
R&D Systems 427-FL-005 image 1
Recombinant Mouse Flt-3 Ligand/FLT3L Protein Bioactivity
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
427-FL
SKU :
427-FL-005
product name :
Recombinant Mouse Flt-3 Ligand/FLT3L Protein
Description :
The Recombinant Mouse Flt-3 Ligand/FLT3L Protein from R&D Systems is derived from NS0. The Recombinant Mouse Flt-3 Ligand/FLT3L Protein has been validated for the following applications: Bioactivity.
target :
Flt-3 Ligand/FLT3L
category :
Proteins and Enzymes
unit size :
5 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
Multiple bands between 18-32 kDa, reducing conditions
theoretical molecular weight :
18 kDa
gene symbol :
Flt3l
details of functionality :
Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with mouse Flt-3. The ED50 for this effect is typically 0.4-2.4 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P49772.1
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Flt-3 Ligand/FLT3L Protein
USD :
181 USD
alt names :
FL, FLG3L, Flt3 ligand, Flt3L, FLT3LG, fms-related tyrosine kinase 3 ligand, SL cytokine
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.