Recombinant Mouse sTNF RII/TNFRSF1B Protein | R&D Systems 426-R2-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse sTNF RII/TNFRSF1B Protein

catalog :

426-R2-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Keeton R, Allie N, Dambuza I, Abel B, Hsu N, Sebesho B, et al. Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis. J Clin Invest. 2014;124:1537-51 pubmed publisher
Osuchowski M, Welch K, Siddiqui J, Remick D. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J Immunol. 2006;177:1967-74 pubmed
Osuchowski M, Siddiqui J, Copeland S, Remick D. Sequential ELISA to profile multiple cytokines from small volumes. J Immunol Methods. 2005;302:172-81 pubmed
Ellaban E, Bolgos G, Remick D. Selective macrophage suppression during sepsis. Cell Immunol. 2004;231:103-11 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

426-R2

SKU :

426-R2-050

product name :

Recombinant Mouse sTNF RII/TNFRSF1B Protein

Description :

The Recombinant Mouse sTNF RII/TNFRSF1B Protein from R&D Systems is derived from E. coli. The Recombinant Mouse sTNF RII/TNFRSF1B Protein has been validated for the following applications: Bioactivity.

target :

TNF RII/TNFRSF1B

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

25 kDa

gene symbol :

Tnfrsf1b

details of functionality :

Measured by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 1-3 µg/mL in the presence of 0.1 ng/mL of recombinant mouse TNF-alpha .

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q545P4

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse sTNF RII/TNFRSF1B Protein

USD :

447 USD

alt names :

CD120b, CD120b antigen, Etanercept, p75 TNF receptor, p75TBPII, p75TNFR, soluble TNFR1B variant 1, TNFBRp80 TNF-alpha receptor, TNF-R2, TNFR2TNFR1B, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor 2, tumor necrosis factor receptor superfamily member 1B, tumor necrosis factor receptor superfamily, member 1B, Tumor necrosis factor receptor type II

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage