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company name :
R&D Systems
product type :
other
product name :
CometAssay Electrophoresis System
catalog :
4250-050-ES
quantity :
1 Kit
price :
2551 USD
more info or order :
citations: 21
Reference
Kovina A, Luzhin A, Tatarskiy V, Deriglazov D, Petrova N, Petrova N, et al. Disruption of RNA Splicing Increases Vulnerability of Cells to DNA-PK Inhibitors. Int J Mol Sci. 2024;25: pubmed publisher
Walton J, Ng A, Arevalo K, Apostoli A, Meens J, Karamboulas C, et al. PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma. Nat Commun. 2024;15:8232 pubmed publisher
Carpenter M, Temiz N, Ibrahim M, Jarvis M, Brown M, Argyris P, et al. Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer. PLoS Genet. 2023;19:e1011043 pubmed publisher
Ramesh S, Cifci A, Javeri S, Minne R, Longhurst C, Nickel K, et al. MET Inhibitor Capmatinib Radiosensitizes MET Exon 14-Mutated and MET-Amplified Non-Small Cell Lung Cancer. bioRxiv. 2023;: pubmed publisher
Ramalingam P, Gutkin M, Poulos M, Tillery T, Doughty C, Winiarski A, et al. Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response. Nat Commun. 2023;14:2018 pubmed publisher
Yoshinaga M, Han K, Morgens D, Horii T, Kobayashi R, Tsuruyama T, et al. The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity. Nat Commun. 2022;13:6435 pubmed publisher
Li M, Zhang R, Xin M, Xu Y, Liu S, Yu B, et al. Discovery and Validation of Potential Serum Biomarkers with Pro-Inflammatory and DNA Damage Activities in Ulcerative Colitis: A Comprehensive Untargeted Metabolomic Study. Metabolites. 2022;12: pubmed publisher
Honjoh H, Tanikawa M, Wada Hiraike O, Oda K, Inaba H, Kukita A, et al. MED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing. Sci Rep. 2022;12:17140 pubmed publisher
Griffin W, McKinzey D, Klinzing K, Baratam R, Eliyapura A, Trakselis M. A multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress. Nat Commun. 2022;13:5090 pubmed publisher
Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé A, et al. Genetic instability from a single S phase after whole-genome duplication. Nature. 2022;604:146-151 pubmed publisher
Mehta K, Thada V, Zhao R, Krishnamoorthy A, Leser M, Lindsey Rose K, et al. CHK1 phosphorylates PRIMPOL to promote replication stress tolerance. Sci Adv. 2022;8:eabm0314 pubmed publisher
Gartrell J, Mellado Largarde M, Clay M, Bahrami A, Sahr N, Sykes A, et al. SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents. Mol Cancer Ther. 2021;20:2151-2165 pubmed publisher
Jian F, Che X, Zhang J, Liu C, Liu G, Tang Y, et al. The long-noncoding RNA SOCS2-AS1 suppresses endometrial cancer progression by regulating AURKA degradation. Cell Death Dis. 2021;12:351 pubmed publisher
Grimley E, Cole A, Luong T, McGonigal S, Sinno S, Yang D, et al. Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors. Theranostics. 2021;11:3540-3551 pubmed publisher
Kaminski P, Hong S, Kono T, Hoover P, Laimins L. Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication. MBio. 2021;12: pubmed publisher
Agundez J, Garcia Martin E, García Laínez G, Miranda M, Andreu I. Photomutagenicity of chlorpromazine and its N-demethylated metabolites assessed by NGS. Sci Rep. 2020;10:6879 pubmed publisher
Martino J, Brunette G, Barroso González J, Moiseeva T, Smith C, Bakkenist C, et al. The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination. Nucleic Acids Res. 2019;47:10151-10165 pubmed publisher
Chen J, Wang Z, Guo X, Li F, Wei Q, Chen X, et al. TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells. Nat Commun. 2019;10:4273 pubmed publisher
Velichko A, Petrova N, Luzhin A, Strelkova O, Ovsyannikova N, Kireev I, et al. Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription. Nucleic Acids Res. 2019;: pubmed publisher
Polkinghorn W, Parker J, Lee M, Kass E, Spratt D, Iaquinta P, et al. Androgen receptor signaling regulates DNA repair in prostate cancers. Cancer Discov. 2013;3:1245-53 pubmed publisher
Jeong Y, Rossi M, Cermak L, Saraf A, Florens L, Washburn M, et al. FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress. J Cell Biol. 2013;200:141-9 pubmed publisher
product information
master code :
4250-050-ES
SKU :
4250-050-ES
product name :
CometAssay Electrophoresis System
unit size :
1 Kit
target :
CometAssays
category :
DNA Damage and Repair Kits
USD :
2551 USD
storage :
The product requires storage at both 2 - 8 ░C and room temperature. Consult the product insert for specific storage temperatures. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.