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company name :
R&D Systems
product type :
other
product name :
CometAssay Lysis Solution (2 x 500 mL)
catalog :
4250-050-01
quantity :
1 L
price :
113 USD
more info or order :
citations: 36
Reference
Sun F, Ali N, Londo xf1 o V xe1 squez D, Simintiras C, Qiao H, Ortega M, et al. Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation. Nat Commun. 2024;15:9463 pubmed publisher
Lim C, Seo D. Assessment of the carcinogenic potential of particulate matter generated from 3D printing devices in Balb/c 3T3-1-1 cells. Sci Rep. 2024;14:23981 pubmed publisher
Jose E, March Steinman W, Wilson B, Shanks L, Parkinson C, Alvarado Cruz I, et al. Temporal coordination of the transcription factor response to H2O2 stress. Nat Commun. 2024;15:3440 pubmed publisher
Meaza I, Williams A, Lu H, Kouokam J, Toyoda J, Croom Perez T, et al. Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial epithelial cells. Toxicol Appl Pharmacol. 2023;479:116711 pubmed publisher
Smith J, Noren Hooten N, Mode N, Zonderman A, Ezike N, Kaushal S, et al. Frailty, sex, and poverty are associated with DNA damage and repair in frail, middle-aged urban adults. DNA Repair (Amst). 2023;129:103530 pubmed publisher
Shimizu N, Hamada Y, Morozumi R, Yamamoto J, Iwai S, Sugiyama K, et al. Repair of topoisomerase 1-induced DNA damage by tyrosyl-DNA phosphodiesterase 2 (TDP2) is dependent on its magnesium binding. J Biol Chem. 2023;299:104988 pubmed publisher
El Ouardi M, Tamarit L, Vay xe1 I, Miranda M, Andreu I. Cellular photo(geno)toxicity of gefitinib after biotransformation. Front Pharmacol. 2023;14:1208075 pubmed publisher
Kim S, Kim Y, Kim Y, Yoon S, Lee K, Lee Y, et al. PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity. PLoS ONE. 2023;18:e0285337 pubmed publisher
Hsieh C, Chang W, Lin C, Chen J, Lin C, Liu C, et al. Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinoma. Am J Cancer Res. 2022;12:5049-5061 pubmed
Meroni A, Grosser J, Agashe S, Ramakrishnan N, Jackson J, Verma P, et al. NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors. Sci Adv. 2022;8:eabq0648 pubmed publisher
Yoshinaga M, Han K, Morgens D, Horii T, Kobayashi R, Tsuruyama T, et al. The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity. Nat Commun. 2022;13:6435 pubmed publisher
Li J, Koczor C, Saville K, Hayat F, Beiser A, McClellan S, et al. Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD+ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase. Cancers (Basel). 2022;14: pubmed publisher
Stefanou D, Kouvela M, Stellas D, Voutetakis K, Papadodima O, Syrigos K, et al. Oxidative Stress and Deregulated DNA Damage Response Network in Lung Cancer Patients. Biomedicines. 2022;10: pubmed publisher
Rashed F, Diaz Dussan D, Mashayekhi F, Macdonald D, Nation P, Yang X, et al. Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents. Redox Biol. 2022;52:102300 pubmed publisher
Jiang B, Murray C, Cole B, Glover J, Chan G, Deschenes J, et al. Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor. Sci Rep. 2022;12:5386 pubmed publisher
Mateos Pujante A, Jiménez M, Andreu I. Evaluation of phototoxicity induced by the anticancer drug rucaparib. Sci Rep. 2022;12:3434 pubmed publisher
Sakata D, Suzuki M, Hirayama R, Abe Y, Muramatsu M, Sato S, et al. Performance Evaluation for Repair of HSGc-C5 Carcinoma Cell Using Geant4-DNA. Cancers (Basel). 2021;13: pubmed publisher
Wang C, Tang M, Chen Z, Nie L, Li S, Xiong Y, et al. Genetic vulnerabilities upon inhibition of DNA damage response. Nucleic Acids Res. 2021;49:8214-8231 pubmed publisher
Wu X, Wang B. Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage. Nat Commun. 2021;12:4373 pubmed publisher
Ren W, Fan H, Grimm S, Kim J, Li L, Guo Y, et al. DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nat Commun. 2021;12:2490 pubmed publisher
Grimley E, Cole A, Luong T, McGonigal S, Sinno S, Yang D, et al. Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors. Theranostics. 2021;11:3540-3551 pubmed publisher
Whelan D, Lee W, Marks F, Kong Y, Yin Y, Rothenberg E. Super-resolution visualization of distinct stalled and broken replication fork structures. PLoS Genet. 2020;16:e1009256 pubmed publisher
Roh Y, Mun J, Kim S, Park W, Jeong M, Kim T, et al. Fanconi Anemia Pathway Activation by FOXM1 Is Critical to Bladder Cancer Recurrence and Anticancer Drug Resistance. Cancers (Basel). 2020;12: pubmed publisher
Agundez J, Garcia Martin E, García Laínez G, Miranda M, Andreu I. Photomutagenicity of chlorpromazine and its N-demethylated metabolites assessed by NGS. Sci Rep. 2020;10:6879 pubmed publisher
Wakita M, Takahashi A, Sano O, Loo T, Imai Y, Narukawa M, et al. A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells. Nat Commun. 2020;11:1935 pubmed publisher
Radhakrishnan K, Park S, Kim S, Hariharasudhan G, Jeong S, Chang I, et al. Karyopherin α-2 Mediates MDC1 Nuclear Import through a Functional Nuclear Localization Signal in the tBRCT Domain of MDC1. Int J Mol Sci. 2020;21: pubmed publisher
Alhumaydhi F, de O Lopes D, Bordin D, Aljohani A, Lloyd C, McNicholas M, et al. Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition. Sci Rep. 2020;10:2209 pubmed publisher
Meng X, Zhao Y, Han B, Zha C, Zhang Y, Li Z, et al. Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways. Nat Commun. 2020;11:594 pubmed publisher
Nytko K, Thumser Henner P, Weyland M, Scheidegger S, Rohrer Bley C. Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro. PLoS ONE. 2019;14:e0216744 pubmed publisher
Mohiuddin M, Rahman M, Sale J, Pearson C. CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs. Nucleic Acids Res. 2019;47:2966-2980 pubmed publisher
Gaulke C, Rolshoven J, Wong C, Hudson L, Ho E, Sharpton T. Marginal Zinc Deficiency and Environmentally Relevant Concentrations of Arsenic Elicit Combined Effects on the Gut Microbiome. mSphere. 2018;3: pubmed publisher
Sykora P, Chiari Y, Heaton A, Moreno N, Glaberman S, Sobol R. Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles. Environ Mol Mutagen. 2018;59:322-333 pubmed publisher
Liu F, Patterson T, Sadovova N, Zhang X, Liu S, Zou X, et al. Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture. Toxicol Sci. 2013;131:548-57 pubmed publisher
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Topham C, Billinton N, Walmsley R. Nongenotoxic apoptosis inducers do not produce misleading positive results in the TK6 cell-based GADD45a-GFP genotoxicity assay. Toxicol Sci. 2012;128:79-91 pubmed publisher
Lee J, Choy M, Ngo L, Venta Perez G, Marks P. Role of checkpoint kinase 1 (Chk1) in the mechanisms of resistance to histone deacetylase inhibitors. Proc Natl Acad Sci U S A. 2011;108:19629-34 pubmed publisher
product information
brand :
R&D Systems
master code :
4250-050-01
SKU :
4250-050-01
product name :
CometAssay Lysis Solution (2 x 500 mL)
unit size :
1 L
target :
CometAssays
category :
DNA Damage and Repair Kits
species :
Multi-Species
USD :
113 USD
storage :
Store the unopened product at room temperature. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.