Recombinant Human/Mouse FGF-8b Protein, CF | R&D Systems 423-F8-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human/Mouse FGF-8b Protein, CF

catalog :

423-F8-025/CF

quantity :

25 ug

price :

302 USD

more info or order :

R&D Systems product webpage

citations: 54

Reference
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Attia L, Schneider J, Yelin R, Schultheiss T. Collective cell migration of the nephric duct requires FGF signaling. Dev Dyn. 2015;244:157-67 pubmed publisher
Yamamoto Shiraishi Y, Higuchi H, Yamamoto S, Hirano M, Kuroiwa A. Etv1 and Ewsr1 cooperatively regulate limb mesenchymal Fgf10 expression in response to apical ectodermal ridge-derived fibroblast growth factor signal. Dev Biol. 2014;394:181-90 pubmed publisher
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Nimmagadda S, Geetha Loganathan P, Scaal M, Christ B, Huang R. FGFs, Wnts and BMPs mediate induction of VEGFR-2 (Quek-1) expression during avian somite development. Dev Biol. 2007;305:421-9 pubmed
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Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, et al. Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. J Neurochem. 2006;98:45-56 pubmed
Hutson M, Zhang P, Stadt H, Sato A, Li Y, Burch J, et al. Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx. Dev Biol. 2006;295:486-97 pubmed
Castelo Branco G, Sousa K, Bryja V, Pinto L, Wagner J, Arenas E. Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Mol Cell Neurosci. 2006;31:251-62 pubmed
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Perrier A, Tabar V, Barberi T, Rubio M, Bruses J, Topf N, et al. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A. 2004;101:12543-8 pubmed
Wiellette E, Sive H. vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain. Development. 2003;130:3821-9 pubmed
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Alsan B, Schultheiss T. Regulation of avian cardiogenesis by Fgf8 signaling. Development. 2002;129:1935-43 pubmed

image

image 1 :

Recombinant Human/Mouse FGF-8b Protein Bioactivity

product information

brand :

R&D Systems

master code :

423-F8/CF

SKU :

423-F8-025/CF

product name :

Recombinant Human/Mouse FGF-8b Protein, CF

description :

The Recombinant Human/Mouse FGF-8b Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human/Mouse FGF-8b Protein, CF has been validated for the following applications: Bioactivity.

target :

FGF-8

category :

Proteins and Enzymes

sizes available :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4 and Brij-35.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human, Mouse

observed molecular weight :

23 kDa, reducing condtions

theoretical molecular weight :

22.5 kDa

gene symbol :

FGF8

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is typically 6.5-40 ng/mL in the presence of 1 µg/mL heparin.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_006110 (human), NP_001159834 (mouse)

applications :

Bioactivity

source :

E. coli-derived Recombinant Human/Mouse FGF-8b Protein, CF

USD :

302

USD 2023 :

302 USD

alt names :

AIGF, AIGFKAL6, Androgen-induced growth factor, FGF8, FGF-8, fibroblast growth factor 8, fibroblast growth factor 8 (androgen-induced), HBGF-8, Heparin-binding growth factor 8, MGC149376

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, 2 to 8 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage