Recombinant Mouse B7-H4 Fc Chimera Protein, CF | R&D Systems 4206-B7-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse B7-H4 Fc Chimera Protein, CF

catalog :

4206-B7-100

quantity :

100 ug (also 1 mg)

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Wang Y, Li R, Yuan R, Wang L, Qiao Q, Han Z, et al. Dehydroepiandrosterone attenuated the immune escape of oral squamous cell carcinoma through NF-κB p65/miR-15b-5p/B7-H4 axis. Int Immunopharmacol. 2024;137:112480 pubmed publisher

product information

master code :

4206-B7

SKU :

4206-B7-100

product name :

Recombinant Mouse B7-H4 Fc Chimera Protein, CF

unit size :

100 ug (also 1 mg)

description :

The Recombinant Mouse B7-H4 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse B7-H4 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

B7-H4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

75-85 kDa, reducing conditions

theoretical molecular weight :

52.4 kDa (monomer)

gene symbol :

Vtcn1

details of functionality :

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells. Human T lymphocytes cultured for 72 hours with PHA were incubated for an additional 3 days in 96 well plates coated with 500 ng/mL anti-CD3 and Recombinant Mouse B7-H4 Fc Chimera. The ED50 for this effect is 0.5-3 ╡g/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAP37284

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse B7-H4 protein Mouse B7-H4 (Phe29-Pro258) Accession # AAP37284 IEGRMDP Mouse IgG2a (Glu98-Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

B7h.5, B7H4, B7-H4, B7H4T-cell costimulatory molecule B7x, B7S1, B7S1VCTN1, B7x, B7XPRO1291, FLJ22418, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, V-set domain containing T cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage