Recombinant Human Apolipoprotein E3 Protein, CF | R&D Systems 4144-AE-500 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Apolipoprotein E3 Protein, CF

catalog :

4144-AE-500

quantity :

500 ug

price :

285 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Leeman H, Kaminska E, Green D, Bodman Smith M, Gravett A, Bodman Smith K, et al. Serum Apolipoprotein E and Other Inflammatory Markers Can Identify Non-Responding Patients to a Dendritic Cell Vaccine. Transl Oncol. 2019;12:397-403 pubmed publisher
Kara E, Marks J, Roe A, Commins C, Fan Z, Calvo Rodríguez M, et al. A flow cytometry-based in vitro assay reveals that formation of apolipoprotein E (ApoE)-amyloid beta complexes depends on ApoE isoform and cell type. J Biol Chem. 2018;293:13247-13256 pubmed publisher
Landowski L, Pavez M, Brown L, Gasperini R, Taylor B, West A, et al. Low-density Lipoprotein Receptor-related Proteins in a Novel Mechanism of Axon Guidance and Peripheral Nerve Regeneration. J Biol Chem. 2016;291:1092-102 pubmed publisher
Wittrup A, Ai A, Liu X, Hamar P, Trifonova R, Charisse K, et al. Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown. Nat Biotechnol. 2015;33:870-6 pubmed publisher
Zhao Y, Ren Y, Zhang X, Zhao P, Tao W, Zhong J, et al. Ficolin-2 inhibits hepatitis C virus infection, whereas apolipoprotein E3 mediates viral immune escape. J Immunol. 2014;193:783-96 pubmed publisher

product information

brand :

R&D Systems

master code :

4144-AE

SKU :

4144-AE-500

product name :

Recombinant Human Apolipoprotein E3 Protein, CF

description :

The Recombinant Human Apolipoprotein E3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Apolipoprotein E3 Protein, CF has been validated for the following applications: Binding Activity.

target :

Apolipoprotein E3/ApoE3

category :

Proteins and Enzymes

sizes available :

500 ug

buffer :

Supplied as a 0.2 µm filtered solution in MOPS, NaCl, CHAPS and TCEP.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

35.2 kDa

gene symbol :

APOE

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Apolipoprotein E3/ApoE3 is immobilized at 1 µg/mL (100 µL/well), the concentration of recombinant mouse VLDL R that produces 50% of the optimal binding response is found to be approximately 0.075 - 0.375 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P02649

applications :

Binding Activity

source :

E. coli-derived Recombinant Human Apolipoprotein E3 Protein, CF

USD :

280

USD 2023 :

285 USD

alt names :

AD2, Apo-E, ApoE4, apolipoprotein E, LDLCQ5, LPG

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage