Recombinant Mouse G-CSF Protein | R&D Systems 414-CS-005 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse G-CSF Protein

catalog :

414-CS-005

quantity :

5 ug

price :

237 USD

more info or order :

R&D Systems product webpage

citations: 18

Reference
Maruyama K, Kidoya H, Takemura N, Sugisawa E, Takeuchi O, Kondo T, et al. Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages. Cell Rep. 2020;32:107906 pubmed publisher
Naranjo Gómez M, Lambour J, Piechaczyk M, Pelegrin M. Neutrophils are essential for induction of vaccine-like effects by antiviral monoclonal antibody immunotherapies. JCI Insight. 2018;3: pubmed publisher
Itoh Nakadai A, Matsumoto M, Kato H, Sasaki J, Uehara Y, Sato Y, et al. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors. Cell Rep. 2017;18:2401-2414 pubmed publisher
Campbell I, Leong D, Edwards K, Rayzman V, Ng M, Goldberg G, et al. Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis. J Immunol. 2016;197:4392-4402 pubmed
Luyten A, Zang C, Liu X, Shivdasani R. Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells. Genes Dev. 2014;28:1827-39 pubmed publisher
Doi Y, Takeuchi H, Mizoguchi H, Fukumoto K, Horiuchi H, Jin S, et al. Granulocyte-colony stimulating factor attenuates oligomeric amyloid β neurotoxicity by activation of neprilysin. PLoS ONE. 2014;9:e103458 pubmed publisher
Gardner J, Noel J, Nikolaidis N, Karns R, Aronow B, Ogle C, et al. G-CSF drives a posttraumatic immune program that protects the host from infection. J Immunol. 2014;192:2405-17 pubmed publisher
Fujihara Y, Takato T, Hoshi K. Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regeneration. Stem Cells. 2014;32:1208-19 pubmed publisher
Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, et al. Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports. 2013;1:545-59 pubmed publisher
Nacionales D, Gentile L, Vanzant E, Lopez M, Cuenca A, Cuenca A, et al. Aged mice are unable to mount an effective myeloid response to sepsis. J Immunol. 2014;192:612-22 pubmed publisher
Yamanishi Y, Takahashi M, Izawa K, Isobe M, Ito S, Tsuchiya A, et al. A soluble form of LMIR5/CD300b amplifies lipopolysaccharide-induced lethal inflammation in sepsis. J Immunol. 2012;189:1773-9 pubmed publisher
Cook B, Liu S, Evans T. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood. 2011;117:6489-97 pubmed publisher
Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, et al. G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell. 2010;6:227-37 pubmed publisher
Shojaei F, Wu X, ZHONG C, Yu L, Liang X, Yao J, et al. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature. 2007;450:825-31 pubmed
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
Kim S, Nguyen A, Gao J, Murphy P, Mansfield B, Chou J. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions. J Biol Chem. 2006;281:28794-801 pubmed
Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett N, et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell. 2002;109:625-37 pubmed
Ye P, Rodriguez F, Kanaly S, Stocking K, Schurr J, Schwarzenberger P, et al. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J Exp Med. 2001;194:519-27 pubmed

product information

brand :

R&D Systems

master code :

414-CS

SKU :

414-CS-005

product name :

Recombinant Mouse G-CSF Protein

unit size :

5 ug

description :

The Recombinant Mouse G-CSF Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse G-CSF Protein, CF has been validated for the following applications: Bioactivity.

target :

G-CSF

category :

Proteins and Enzymes

alt names :

C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3, CSF3OS, Filgrastim, GCSF, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin

buffer :

Lyophilized from a 0.2 µm filtered solution in Citric Acid and Tween® 20 with BSA as a carrier protein.

conjugate :

Unconjugated

all available conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

theoretical molecular weight :

19 kDa

gene symbol :

Csf3

details of functionality :

Measured in a cell proliferation assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. Shirafuji, N. et al . (1989) Exp. Hematol. 17 :116. The ED50 for this effect is 10-60 pg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P09920

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse G-CSF Protein

USD :

219

Jul-22 :

237 USD

sizes available :

5 ug (also 25 ug)

more info or order :

R&D Systems product webpage