Recombinant Human KIR3DS1/CD158e2 Fc Chimera Protein, CF | R&D Systems 4136-KR-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human KIR3DS1/CD158e2 Fc Chimera Protein, CF

catalog :

4136-KR-050

quantity :

50 ug

price :

507 USD

citations: 4

Reference
Tremblay McLean A, Coenraads S, Kiani Z, Dupuy F, Bernard N. Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function. BMC Immunol. 2019;20:8 pubmed publisher
Kiani Z, Dupuy F, Bruneau J, Lebouché B, Zhang C, Jackson E, et al. HLA-F on HLA-Null 721.221 Cells Activates Primary NK Cells Expressing the Activating Killer Ig-like Receptor KIR3DS1. J Immunol. 2018;201:113-123 pubmed publisher
Ryser S, Estelles A, Tenorio E, KAUVAR L, Gishizky M. High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals. PLoS ONE. 2017;12:e0181464 pubmed publisher
Fadda L, Korner C, Kumar S, van Teijlingen N, Piechocka Trocha A, Carrington M, et al. HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function. PLoS Pathog. 2012;8:e1002805 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

4136-KR

SKU :

4136-KR-050

product name :

Recombinant Human KIR3DS1/CD158e2 Fc Chimera Protein, CF

Description :

The Recombinant Human KIR3DS1/CD158e2 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human KIR3DS1/CD158e2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

KIR3DS1/CD158e2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

75-90 kDa, reducing conditions

theoretical molecular weight :

61.9 kDa (monomer)

gene symbol :

KIR3DS1

details of functionality :

Measured by its ability to bind HLA on MDA-MB-231 human breast cancer cells. The ED50 for this effect is 0.03-0.18 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q14943

applications :

Binding Activity

source :

CHO-derived Recombinant Human KIR3DS1/CD158e2 Fc Chimera Protein

USD :

507 USD

alt names :

CD158e2, CD158E2;Killer cell immunoglobulin-like receptor 3DS1;KIR-123FM;KIR-G1;NKAT10;NKAT-10, KIR-G1, nkat10

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.