Recombinant Mouse TNF-alpha (aa 84-235) Protein, CF | R&D Systems 410-TRNC-010/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TNF-alpha (aa 84-235) Protein, CF

catalog :

410-TRNC-010/CF

quantity :

10 ug (also 50 ug)

price :

312 USD

citations: 5

Reference
Ji D, Yamashiro L, Chen K, Mukaida N, Kramnik I, Darwin K, et al. Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra. Nat Microbiol. 2019;4:2128-2135 pubmed publisher
Garner K, Betin V, Pinto V, Graham M, Abgueguen E, Barnes M, et al. Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress. Sci Rep. 2018;8:3902 pubmed publisher
Jules J, Wang S, Shi Z, Liu J, Wei S, Feng X. The IVVY Motif and Tumor Necrosis Factor Receptor-associated Factor (TRAF) Sites in the Cytoplasmic Domain of the Receptor Activator of Nuclear Factor ÎºB (RANK) Cooperate to Induce Osteoclastogenesis. J Biol Chem. 2015;290:23738-50 pubmed publisher
Jules J, Shi Z, Liu J, Xu D, Wang S, Feng X. Receptor activator of NF-{kappa}B (RANK) cytoplasmic IVVY535-538 motif plays an essential role in tumor necrosis factor-{alpha} (TNF)-mediated osteoclastogenesis. J Biol Chem. 2010;285:37427-35 pubmed publisher
Liu W, Xu D, Yang H, Xu H, Shi Z, Cao X, et al. Functional identification of three receptor activator of NF-kappa B cytoplasmic motifs mediating osteoclast differentiation and function. J Biol Chem. 2004;279:54759-69 pubmed

product information

master code :

410-TRNC/CF

SKU :

410-TRNC-010/CF

product name :

Recombinant Mouse TNF-alpha (aa 84-235) Protein, CF

unit size :

10 ug (also 50 ug)

description :

The Recombinant Mouse TNF-alpha (aa 84-235) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse TNF-alpha (aa 84-235) Protein, CF has been validated for the following applications: Bioactivity.

target :

TNF-alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

theoretical molecular weight :

17 kDa (monomer)

gene symbol :

Tnf

details of functionality :

Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycináD. Matthews,áN. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 0.8-4 pg/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P06804

applications :

Bioactivity

source long :

E. coli -derived mouse TNF-alpha protein Ser84-Leu235

source short :

E. coli

USD :

312 USD

alt names :

APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.