product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-9 Protein
catalog :
409-ML-010
quantity :
10 ug (also 50 ug)
price :
416 USD
more info or order :
R&D Systems product webpage
citations: 11
Reference
Deng K, Yang X, Luo Q, She Y, Yu Q, Tang X. Deleterious Role of Th9 Cells in Pulmonary Fibrosis. Cells. 2021;10: pubmed publisher
Yashiro T, Ogata H, Zaidi S, Lee J, Hayashi S, Yamamoto T, et al. Pathophysiological Roles of Neuro-Immune Interactions between Enteric Neurons and Mucosal Mast Cells in the Gut of Food Allergy Mice. Cells. 2021;10: pubmed publisher
Liu X, Zhou F, Wang W, Chen G, Zhang Q, Lv R, et al. IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis. J Neuroinflammation. 2021;18:108 pubmed publisher
Almeida R, Vieira R, Castoldi A, Terra F, Melo A, Canesso M, et al. Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity. Br J Cancer. 2020;123:534-541 pubmed publisher
Liu N, Jiang Y, Chen J, Nan H, Zhao Y, Chu X, et al. IL-33 drives the antitumor effects of dendritic cells via the induction of Tc9 cells. Cell Mol Immunol. 2018;: pubmed publisher
Turner J, Morrison P, Wilhelm C, Wilson M, Ahlfors H, Renauld J, et al. IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med. 2013;210:2951-65 pubmed publisher
Purwar R, Schlapbach C, Xiao S, Kang H, Elyaman W, Jiang X, et al. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012;18:1248-53 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J Virol. 2010;84:12703-12 pubmed publisher
Vang K, Yang J, Mahmud S, Burchill M, Vegoe A, Farrar M. IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development. J Immunol. 2008;181:3285-90 pubmed
Reader J, Hyde D, Schelegle E, Aldrich M, Stoddard A, McLane M, et al. Interleukin-9 induces mucous cell metaplasia independent of inflammation. Am J Respir Cell Mol Biol. 2003;28:664-72 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
409-ML
SKU :
409-ML-010
product name :
Recombinant Mouse IL-9 Protein
Description :
The Recombinant Mouse IL-9 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse IL-9 Protein has been validated for the following applications: Bioactivity.
target :
IL-9
category :
Proteins and Enzymes
unit size :
10 ug (also 50 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
Multiple bands between 16-25 kDa, reducing conditions
theoretical molecular weight :
14.2 kDa
gene symbol :
Il9
details of functionality :
Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 0.500-5.00 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P15247
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Mouse IL-9 Protein
USD :
416 USD
alt names :
Cytokine P40, HP40, IL9, IL-9homolog of mouse T cell and mast cell growth factor 40, interleukin 9, interleukin-9, P40, p40 cytokine, p40 T-cell and mast cell growth factor, T-cell growth factor P40
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.